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A Jak2-selective inhibitor potently reverses the immune suppression by modulating the tumor microenvironment for cancer immunotherapy Journal article
BIOCHEMICAL PHARMACOLOGY, 2017,Volume: 145,Page: 132-146
Authors:  He, Wei;  Zhu, Yi;  Mu, Ruoyu;  Xu, Jinzhi;  Zhang, Xiaoyi;  Wang, Chunming;  Li, Qiu;  Huang, Zhen;  Zhang, Junfeng;  Pan, Yi;  Han, Jianlin;  Dong, Lei
Favorite | View/Download:24/0 | TC[WOS]:5 TC[Scopus]:0 | Submit date:2018/10/30
Tumor Associated Macrophages  Regulatory t Cells  Jak2-stat3 Pathway  Tumor Immunotherapy  
A natural product-like JAK2/STAT3 inhibitor induces apoptosis of malignant melanoma cells Journal article
PLOS ONE, 2017,Volume: 12,Issue: 6
Authors:  Wu, Ke-Jia;  Huang, Jie-Min;  Zhong, Hai-Jing;  Dong, Zhen-Zhen;  Vellaisamy, Kasipandi;  Lu, Jin-Jian;  Chen, Xiu-Ping;  Chiu, Pauline;  Kwong, Daniel W. J.;  Han, Quan-Bin;  Ma, Dik-Lung;  Leung, Chung-Hang
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In silico identification of natural product inhibitors of JAK2 Journal article
Methods, 2015,Volume: 71,Issue: C,Page: 21-25
Authors:  Zhong H.-J.;  Lin S.;  Tam I.L.;  Lu L.;  Chan D.S.-H.;  Ma D.-L.;  Leung C.-H.
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6-chloroemodic Acid  Emodic Acid  Jak2  Natural Product  Virtual Screening  
Virtual screening and optimization of type II inhibitors of JAK2 from a natural product library Journal article
Chemical Communications, 2014,Volume: 50,Issue: 90,Page: 13859–14054
Authors:  Ma D.-L.;  Chan D.S.-H.;  Wei G.;  Zhong H.-J.;  Yang H.;  Leung L.T.;  Gullen E.A.;  Chiu P.;  Cheng Y.-C.;  Leung C.-H.
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Group 9 organometallic compounds for therapeutic and bioanalytical applications Journal article
Accounts of Chemical Research, 2014,Volume: 47,Issue: 12,Page: 3614−3631
Authors:  Ma D.-L.;  Chan D.S.-H.;  Leung C.-H.
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Inhibition of Janus kinase 2 by cyclometalated rhodium complexes Journal article
MedChemComm, 2012,Volume: 3,Issue: 6,Page: 696-698
Authors:  Leung C.-H.;  Yang H.;  Ma V.P.-Y.;  Chan D.S.-H.;  Zhong H.-J.;  Li Y.-W.;  Fong W.-F.;  Ma D.-L.
Favorite | View/Download:6/0 | TC[WOS]:24 TC[Scopus]:0 | Submit date:2018/11/06