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Computer-Aided Formulation Design for a Highly Soluble Lutein-Cyclodextrin Multiple-Component Delivery System Journal article
MOLECULAR PHARMACEUTICS, 2018,Volume: 15,Issue: 4,Page: 1664-1673
Authors:  Zhao, Qianqian;  Miriyala, Nikhila;  Su, Yan;  Chen, Weijie;  Gao, Xuejiao;  Shao, Ling;  Yan, Ru;  Li, Haifeng;  Yao, Xiaojun;  Cao, Dongsheng;  Wang, Yitao;  Ouyang, Defang
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Lutein  Cyclodextrin  Multiple-component System  Molecular Dynamics Simulation  Bioavailability  Computer-aided Formulation Design  
Simultaneous targeting of NPC1 and VDAC1 by itraconazole leads to synergistic inhibition of MTOR signaling and angiogenesis Journal article
ACS Chemical Biology, 2017,Volume: 12,Issue: 1,Page: 174
Authors:  Head S.A.;  Shi W.Q.;  Yang E.J.;  Nacev B.A.;  Hong S.Y.;  Pasunooti K.K.;  Li R.-J.;  Shim J.S.;  Liu J.O.
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Simultaneous Targeting of NPC1 and VDAC1 by Itraconazole Leads to Synergistic Inhibition of mTOR Signaling and Angiogenesis Journal article
ACS CHEMICAL BIOLOGY, 2017,Volume: 12,Issue: 1,Page: 174-182
Authors:  Head, Sarah A.;  Shi, Wei Q.;  Yang, Eun Ju;  Nacev, Benjamin A.;  Hong, Sam Y.;  Pasunooti, Kalyan K.;  Li, Ruo-Jing;  Shim, Joong Sup;  Liu, Jun O.
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Divergence of antiangiogenic activity and hepatotoxicity of different stereoisomers of itraconazole Journal article
Clinical Cancer Research, 2016,Volume: 22,Issue: 11,Page: 2709-2720
Authors:  Shim J.S.;  Li R.-J.;  Bumpus N.N.;  Head S.A.;  Pasunooti K.K.;  Yang E.J.;  Lv J.;  Shi W.;  Liu J.O.
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Divergence of anti-angiogenic activity and hepatotoxicity of different stereoisomers of itraconazole Journal article
Clinical Cancer Research, 2016,Volume: 22,Issue: 11,Page: 2709-2720
Authors:  Joong Sup Shim;  Ruo-Jing Li;  Namandje N. Bumpus;  Sarah A. Head;  Kalyan Kumar;  Eun Ju Yang;  Junfang Lv;  Wei Shi;  Jun O. Liu
Favorite  |  View/Download:2/0  |  Submit date:2019/01/24
Itraconazole  Stereoisomers  Drug Repositioning  Angiogenesis  Hepatotoxicity  
Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells Journal article
Proceedings of the National Academy of Sciences of the United States of America, 2015,Volume: 112,Issue: 52,Page: E7276
Authors:  Head S.A.;  Shi W.;  Zhao L.;  Gorshkov K.;  Pasunooti K.;  Chen Y.;  Deng Z.;  Li R.-J.;  Shim J.S.;  Tan W.;  Hartung T.;  Zhang J.;  Zhao Y.;  Colombini M.;  Liu J.O.
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Angiogenesis  Itraconazole  Metabolism  Mitochondria  VDAC1  
The antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells Journal article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2015,Volume: 112,Issue: 52,Page: E7276-E7285
Authors:  Sarah A. Head;  Wei Shi;  Liang Zhao;  Kirill Gorshkov;  Kalyan Pasunooti;  Yue Chen;  Zhiyou Deng;  Ruo-jing Li;  Joong Sup Shim;  Wenzhi Tan;  Thomas Hartung;  Jin Zhang;  Yingming Zhao;  Marco Colombini;  Jun O. Liu
Favorite  |  View/Download:3/0  |  Submit date:2019/01/24
Angiogenesis  Mitochondria  Metabolism  Itraconazole  Vdac1