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Neural stem cells for disease modeling and evaluation of therapeutics for Tay-Sachs disease Journal article
ORPHANET JOURNAL OF RARE DISEASES, 2018,Volume: 13
Authors:  Vu, Mylinh;  Li, Rong;  Baskfield, Amanda;  Lu, Billy;  Farkhondeh, Atena;  Gorshkov, Kirill;  Motabar, Omid;  Beers, Jeanette;  Chen, Guokai;  Zou, Jizhong;  Espejo-Mojica, Angela J.;  Rodriguez-Lopez, Alexander;  Almeciga-Diaz, Carlos J.;  Barrera, Luis A.;  Jiang, Xuntian;  Ory, Daniel S.;  Marugan, Juan J.;  Zheng, Wei
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Tay-Sachs disease  Induced pluripotent stem cells  Neural stem cells  Cyclodextrin  HP beta CD  delta-tocopherol  Enzyme replacement therapy  Hexosaminidase A  GM2 gangliosidosis  High throughput screening  Drug discovery  
Presenilin 1 deficiency suppresses autophagy in human neural stem cells through reducing γ-secretase-independent ERK/CREB signaling Journal article
CELL DEATH & DISEASE, 2018,Volume: 9,Page: 1-13
Authors:  Cheong-Meng Chong;  Minjing Ke;  Yuan Tan;  Zhijian Huang;  Ke Zhang;  Nana Ai;  Wei Ge;  Dajiang Qin;  Jia-Hong Lu;  Huanxing Su
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Generation of an induced pluripotent stem cell line from an adult male with 45,X/46,XY mosaicism Journal article
STEM CELL RESEARCH, 2018,Volume: 27,Page: 42-45
Authors:  Luo, Yumei;  Zhu, Detu;  Xu, Xiangye;  Ge, Lingxia;  Sun, Xiaofang;  Chen, Guokai;  Chen, Yaoyong
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Modeling the Pathogenesis of Charcot-Marie-Tooth Disease Type 1A Using Patient-Specific iPSCs Journal article
STEM CELL REPORTS, 2018,Volume: 10,Issue: 1,Page: 120-133
Authors:  Shi, Lei;  Huang, Lihua;  He, Ruojie;  Huang, Weijun;  Wang, Huiyan;  Lai, Xingqiang;  Zou, Zhengwei;  Sun, Jiaqi;  Ke, Qiong;  Zheng, Minying;  Lu, Xilin;  Pei, Zhong;  Su, Huanxing;  Xiang, Andy Peng;  Li, Weiqiang;  Yao, Xiaoli
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Presenilin 1 deficiency suppresses autophagy in human neural stem cells through reducing γ-secretase-independent ERK/CREB signaling Journal article
Cell Death and Disease, 2018,Volume: 9,Issue: 9
Authors:  Chong C.-M.;  Ke M.;  Tan Y.;  Huang Z.;  Zhang K.;  Ai N.;  Ge W.;  Qin D.;  Lu J.-H.;  Su H.
Favorite  |  View/Download:3/0  |  Submit date:2018/12/11
ASXL3 is a novel pluripotency factor in human respiratory epithelial cells and a potential therapeutic target in small cell lung cancer Journal article
Cancer Research, 2017,Volume: 77,Issue: 22,Page: 6267-6281
Authors:  Shukla V.;  Rao M.;  Zhang H.;  Beers J.;  Wangsa D.;  Wangsa D.;  Buishand F.O.;  Wang Y.;  Yu Z.;  Stevenson H.S.;  Reardon E.S.;  McLoughlin K.C.;  Kaufman A.S.;  Payabyab E.C.;  Hong J.A.;  Zhang M.;  Davis S.;  Edelman D.;  Chen G.;  Miettinen M.M.;  Restifo N.P.;  Ried T.;  Meltzer P.A.;  Schrump D.S.
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Temporal establishment of neural cell identity in vivo and in vitro Journal article
JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 2017,Volume: 11,Issue: 9,Page: 2582-2589
Authors:  Yuen, Shun Ming;  Kwok, Hang Fai
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Temporal Regulation  Neural Stem Cells  Embryonic Stem Cells  Induced Pluripotent Stem Cells  Cis-regulatory Elements  Cell Fates  Neural Specification  
Heparin Promotes Cardiac Differentiation of Human Pluripotent Stem Cells in Chemically Defined Albumin-Free Medium, Enabling Consistent Manufacture of Cardiomyocytes Journal article
STEM CELLS TRANSLATIONAL MEDICINE, 2017,Volume: 6,Issue: 2,Page: 527-538
Authors:  Lin, Yongshun;  Linask, Kaari L.;  Mallon, Barbara;  Johnson, Kory;  Klein, Michael;  Beers, Jeanette;  Xie, Wen;  Du, Yubin;  Liu, Chengyu;  Lai, Yinzhi;  Zou, Jizhong;  Haigney, Mark;  Yang, Hushan;  Rao, Mahendra;  Chen, Guokai
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Cardiac  Cell culture  Embryonic stem cells  Induced pluripotent stem cells  Heparin  
Heparin promotes cardiac differentiation of human pluripotent stem cells in chemically defined albumin-free medium, enabling consistent manufacture of cardiomyocytes Journal article
Stem Cells Translational Medicine, 2017,Volume: 6,Issue: 2,Page: 527-538
Authors:  Lin Y.;  Linask K.L.;  Mallon B.;  Johnson K.;  Klein M.;  Beers J.;  Xie W.;  Du Y.;  Liu C.;  Lai Y.;  Zou J.;  Haigney M.;  Yang H.;  Rao M.;  Chen G.
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Cardiac  Cell Culture  Embryonic Stem Cells  Heparin  Induced Pluripotent Stem Cells  
Recapitulating and correcting marfan syndrome in a cellular model Journal article
International Journal of Biological Sciences, 2017,Volume: 13,Issue: 5,Page: 588-603
Authors:  Park J.W.;  Yan L.;  Stoddard C.;  Wang X.;  Yue Z.;  Crandall L.;  Robinson T.;  Chang Y.;  Denton K.;  Li E.;  Jiang B.;  Zhang Z.;  Martins-Taylor K.;  Yee S.-P.;  Nie H.;  Gu F.;  Si W.;  Xie T.;  Yue L.;  Xu R.-H.
Favorite  |  View/Download:5/0  |  Submit date:2018/12/20
Disease Modeling  Genome Editing  Human Pluripotent Stem Cells  Marfan Syndrome  Osteogenesis  Smooth Muscle