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Hydroxyurea Facilitates Manifestation of Disease Relevant Phenotypes in Patients-Derived IPSCs-Based Modeling of Late-Onset Parkinson’s Disease Journal article
AGING AND DISEASE, 2019,Volume: 10,Issue: 5,Page: 1037-1048
Authors:  Yuan Tan;  Minjing Ke;  Zhijian Huang;  Cheong-Meng Chong;  Xiaotong Cen;  Jia-Hong Lu;  Xiaoli Yao;  Dajiang Qin;  Huanxing Su
Favorite | View/Download:18/0 | TC[WOS]:2 TC[Scopus]:0 | Submit date:2020/04/08
Disease Phenotypes  Er Stress  Induced Pluripotentstem Cells  Parkinson’s Disease  Hydroxyurea  
Using induced pluripotent stem cells for modeling Parkinson’s disease Journal article
WORLD JOURNAL OF STEM CELLS, 2019,Volume: 11,Issue: 9,Page: 634-649
Authors:  Minjing Ke;  Cheong-Meng Chong;  Huanxing Su
Favorite | View/Download:14/0 | TC[WOS]:2 TC[Scopus]:0 | Submit date:2020/04/08
Parkinson’s Disease  Dopaminergic Neurons  Induced Pluripotent Stem Cells  Somatic Cell Reprogramming  Aging  
Generation of Human Fatty Livers Using Custom-Engineered Induced Pluripotent Stem Cells with Modifiable SIRT1 Metabolism Journal article
Cell Metabolism, 2019,Volume: 30,Issue: 2,Page: 385-401.e9
Authors:  Collin de l'Hortet,Alexandra;  Takeishi,Kazuki;  Guzman-Lepe,J.;  Morita,Kazutoyo;  Achreja,Abhinav;  Popovic,Branimir;  Wang,Yang;  Handa,Kan;  Mittal,Anjali;  Meurs,Noah;  Zhu,Z.;  Weinberg,F.;  Salomon,Michael;  Fox,I. J.;  Deng,Chu Xia;  Nagrath,Deepak;  Soto-Gutierrez,Alejandro
Favorite | View/Download:73/0 | TC[WOS]:10 TC[Scopus]:11 | Submit date:2020/09/16
cellular engineering  hepatic differentiation  human fatty liver  human iPSCs  liver metabolism  NAFLD  NASH  SIRT1  
Neural stem cells for disease modeling and evaluation of therapeutics for Tay-Sachs disease Journal article
ORPHANET JOURNAL OF RARE DISEASES, 2018,Volume: 13
Authors:  Vu, Mylinh;  Li, Rong;  Baskfield, Amanda;  Lu, Billy;  Farkhondeh, Atena;  Gorshkov, Kirill;  Motabar, Omid;  Beers, Jeanette;  Chen, Guokai;  Zou, Jizhong;  Espejo-Mojica, Angela J.;  Rodriguez-Lopez, Alexander;  Almeciga-Diaz, Carlos J.;  Barrera, Luis A.;  Jiang, Xuntian;  Ory, Daniel S.;  Marugan, Juan J.;  Zheng, Wei
Favorite | View/Download:61/0 | TC[WOS]:4 TC[Scopus]:0 | Submit date:2018/10/30
Tay-sachs Disease  Induced Pluripotent Stem Cells  Neural Stem Cells  Cyclodextrin  Hp Beta Cd  Delta-tocopherol  Enzyme Replacement Therapy  Hexosaminidase a  Gm2 Gangliosidosis  High Throughput Screening  Drug Discovery  
Presenilin 1 deficiency suppresses autophagy in human neural stem cells through reducing γ-secretase-independent ERK/CREB signaling Journal article
CELL DEATH & DISEASE, 2018,Volume: 9,Page: 1-13
Authors:  Cheong-Meng Chong;  Minjing Ke;  Yuan Tan;  Zhijian Huang;  Ke Zhang;  Nana Ai;  Wei Ge;  Dajiang Qin;  Jia-Hong Lu;  Huanxing Su
Favorite | View/Download:40/0 | TC[WOS]:11 TC[Scopus]:0 | Submit date:2018/10/30
Generation of an induced pluripotent stem cell line from an adult male with 45,X/46,XY mosaicism Journal article
STEM CELL RESEARCH, 2018,Volume: 27,Page: 42-45
Authors:  Luo, Yumei;  Zhu, Detu;  Xu, Xiangye;  Ge, Lingxia;  Sun, Xiaofang;  Chen, Guokai;  Chen, Yaoyong
Favorite | View/Download:18/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2018/10/30
Modeling the Pathogenesis of Charcot-Marie-Tooth Disease Type 1A Using Patient-Specific iPSCs Journal article
STEM CELL REPORTS, 2018,Volume: 10,Issue: 1,Page: 120-133
Authors:  Shi, Lei;  Huang, Lihua;  He, Ruojie;  Huang, Weijun;  Wang, Huiyan;  Lai, Xingqiang;  Zou, Zhengwei;  Sun, Jiaqi;  Ke, Qiong;  Zheng, Minying;  Lu, Xilin;  Pei, Zhong;  Su, Huanxing;  Xiang, Andy Peng;  Li, Weiqiang;  Yao, Xiaoli
Favorite | View/Download:29/0 | TC[WOS]:4 TC[Scopus]:0 | Submit date:2018/10/30
ASXL3 is a novel pluripotency factor in human respiratory epithelial cells and a potential therapeutic target in small cell lung cancer Journal article
Cancer Research, 2017,Volume: 77,Issue: 22,Page: 6267-6281
Authors:  Shukla V.;  Rao M.;  Zhang H.;  Beers J.;  Wangsa D.;  Wangsa D.;  Buishand F.O.;  Wang Y.;  Yu Z.;  Stevenson H.S.;  Reardon E.S.;  McLoughlin K.C.;  Kaufman A.S.;  Payabyab E.C.;  Hong J.A.;  Zhang M.;  Davis S.;  Edelman D.;  Chen G.;  Miettinen M.M.;  Restifo N.P.;  Ried T.;  Meltzer P.A.;  Schrump D.S.
Favorite | View/Download:11/0 | TC[WOS]:3 TC[Scopus]:0 | Submit date:2018/12/21
Temporal establishment of neural cell identity in vivo and in vitro Journal article
JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 2017,Volume: 11,Issue: 9,Page: 2582-2589
Authors:  Yuen, Shun Ming;  Kwok, Hang Fai
Favorite | View/Download:17/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2018/10/30
Temporal Regulation  Neural Stem Cells  Embryonic Stem Cells  Induced Pluripotent Stem Cells  Cis-regulatory Elements  Cell Fates  Neural Specification  
Heparin promotes cardiac differentiation of human pluripotent stem cells in chemically defined albumin-free medium, enabling consistent manufacture of cardiomyocytes Journal article
Stem Cells Translational Medicine, 2017,Volume: 6,Issue: 2,Page: 527-538
Authors:  Lin Y.;  Linask K.L.;  Mallon B.;  Johnson K.;  Klein M.;  Beers J.;  Xie W.;  Du Y.;  Liu C.;  Lai Y.;  Zou J.;  Haigney M.;  Yang H.;  Rao M.;  Chen G.
Favorite | View/Download:6/0 | TC[WOS]:19 TC[Scopus]:0 | Submit date:2018/12/21
Cardiac  Cell Culture  Embryonic Stem Cells  Heparin  Induced Pluripotent Stem Cells