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Low-toxicity FePt nanoparticles for the targeted and enhanced diagnosis of breast tumors using few centimeters deep whole-body photoacoustic imaging Journal article
Photoacoustics, 2020,Volume: 19
Authors:  Liu,Yubin;  Wu,Pei Chun;  Guo,Sen;  Chou,Pi Tai;  Deng,Chuxia;  Chou,Shang Wei;  Yuan,Zhen;  Liu,Tzu Ming
Favorite | View/Download:138/0 | TC[WOS]:0 TC[Scopus]:1 | Submit date:2020/09/16
Breast cancer  FePt nanoparticles  Imaging depth  Whole-body photoacoustic imaging  
Class I histone deacetylase inhibition is synthetic lethal with BRCA1 deficiency in breast cancer cells Journal article
Acta Pharmaceutica Sinica B, 2020,Volume: 10,Issue: 4,Page: 615-627
Authors:  Zhang,Baoyuan;  Lyu,Junfang;  Yang,Eun Ju;  Liu,Yifan;  Wu,Changjie;  Pardeshi,Lakhansing;  Tan,Kaeling;  Chen,Qiang;  Xu,Xiaoling;  Deng,Chu Xia;  Shim,Joong Sup
Favorite | View/Download:76/0 | TC[WOS]:0 TC[Scopus]:4 | Submit date:2020/09/16
BRCA1  Breast cancer  DNA damage  HDAC  Histone deacetylase  Reactive oxygen species  Synthetic lethality  
Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 9,Page: 1193-1204
Authors:  Ting-ting Zhou;  Tong Zhao;  Fei Ma;  Yi-nan Zhang;  Jing Jiang;  Yuan Ruan;  Qiu-ying Yan;  Gai-hong Wang;  Jin Ren;  Xiao-wei Guan;  Jun Guo;  Yong-hua Zhao;  Ji-ming Ye;  Li-hong Hu;  Jing Chen;  Xu Shen
Favorite | View/Download:14/0 | TC[WOS]:1 TC[Scopus]:1 | Submit date:2020/04/14
Type 2 Diabetes Mellitus  Hepatic Gluconeogenesis  Ampk Signaling Pathway  (e)-3-(2-(Quinoline-4-yl)Vinyl)-1h-indol-6-ol (Qvo)  4-[2-(1h-indol-3-yl)Vinyl]Quinoline (Ivq)  Prodrug  
ATP13A2 facilitates HDAC6 recruitment to lysosome to promote autophagosome–lysosome fusion Journal article
JOURNAL OF CELL BIOLOGY, 2019,Volume: 218,Issue: 1,Page: 267-284
Authors:  Ruoxi Wang;  Jieqiong Tan;  Tingting Chen;  Hailong Han;  Runyi Tian;  Ya Tan;  Yiming Wu;  Jingyi Cu;  Fang Chen;  Jie Li;  Lu Lv;  Xinjie Guan;  Shuai Shang;  Jiahong Lu;  Zhuohua Zhang
Favorite | View/Download:21/0 | TC[WOS]:11 TC[Scopus]:19 | Submit date:2020/04/14
The influence of physiological environment on the targeting effect of aptamer-guided gold nanoparticles Journal article
NANO RESEARCH, 2019,Volume: 12,Issue: 1,Page: 129-135
Authors:  Ding, Ding;  Zhang, Yinling;  Sykes, Edward A.;  Chen, Long;  Chen, Zhuo;  Tan, Weihong
Favorite | View/Download:11/0 | TC[WOS]:7 TC[Scopus]:10 | Submit date:2019/01/17
targeting effect  aptamer  nanomedicine  physiological environment  
Inhibition of lung cancer by 2-methoxy-6-acetyl-7-methyljuglone (MAM) through induction of necroptosis by targeting receptor-interacting protein 1 (RIP1) Journal article
Antioxidants & Redox Signaling, 2018,Volume: 0,Issue: JA
Authors:  Sun W;  Yu J;  Gao H;  Wu X;  Wang S;  Hou Y;  Lu JJ;  Chen X
Favorite | View/Download:29/0 | TC[WOS]:0 TC[Scopus]:8 | Submit date:2019/01/16
para-Aminothiophenol Radical Reaction-Functionalized Gold Nanoprobe for One-to-All Detection of Five Reactive Oxygen Species In Vivo Journal article
ANALYTICAL CHEMISTRY, 2018,Volume: 90,Issue: 20,Page: 12137-12144
Authors:  Kai Cui;  Chenchen Fan;  Gaoxian Chen;  Yuanyuan Qiu;  Mingwang Li;  Miao Lin;  Jian-Bo Wan;  Changsi Cai;  Zeyu Xiao
Favorite | View/Download:22/0 | TC[WOS]:6 TC[Scopus]:10 | Submit date:2020/04/22
Selective Inhibition of Lysine-Specific Demethylase 5A (KDM5A) Using a Rhodium(III) Complex for Triple-Negative Breast Cancer Therapy Journal article
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018,Volume: 57,Issue: 40,Page: 13091-13095
Authors:  Yang, Guan-Jun;  Wang, Wanhe;  Mok, Simon Wing Fai;  Wu, Chun;  Law, Betty Yuen Kwan;  Miao, Xiang-Min;  Wu, Ke-Jia;  Zhong, Hai-Jing;  Wong, Chun-Yuen;  Wong, Vincent Kam Wai;  Ma, Dik-Lung;  Leung, Chung-Hang
Favorite | View/Download:51/0 | TC[WOS]:36 TC[Scopus]:49 | Submit date:2018/10/30
Drug Discovery  Epigenetics  Medicinal Chemistry  Triple-negative Breast Cancer  
Toosendanin, a natural product, inhibited TGF-1-induced epithelial-mesenchymal transition through ERK/Snail pathway Journal article
PHYTOTHERAPY RESEARCH, 2018,Volume: 32,Issue: 10,Page: 2009-2020
Authors:  Luo, Weiwei;  Liu, Xin;  Sun, Wen;  Lu, Jin-Jian;  Wang, Yitao;  Chen, Xiuping
View | Adobe PDF | Favorite | View/Download:848/46 | TC[WOS]:4 TC[Scopus]:11 | Submit date:2018/10/30
Emt  Erk1/2  Snail  Lung Cancer  Toosendanin  
Serum amyloid A promotes LPS clearance and suppresses LPS-induced inflammation and tissue injury Journal article
EMBO REPORTS, 2018,Volume: 19,Issue: 10
Authors:  Cheng, Ni;  Liang, Yurong;  Du, Xiaoping;  Ye, Richard D.
View | Adobe PDF | Favorite | View/Download:577/22 | TC[WOS]:10 TC[Scopus]:18 | Submit date:2018/10/30
acute-phase response  inflammation  innate immunity  lipopolysaccharide  serum amyloid A