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Icaritin suppresses development of neuroendocrine differentiation of prostate cancer through inhibition of IL-6/STAT3 and Aurora kinase A pathways in TRAMP mice Journal article
Carcinogenesis, 2016,Volume: 37,Issue: 7,Page: 701-711
Authors:  Sun F.;  Zhang Z.W.;  Tan E.M.;  Lim Z.L.R.;  Li Y.;  Wang X.C.;  Chua S.E.;  Li J.;  Cheung E.;  Yong E.-L.
Favorite  |  View/Download:5/0  |  Submit date:2018/12/17
Identification of Icaritin Metabolites in Rats by LC-MS/MS Journal article
Chinese Herbal Medicines, 2015,Volume: 7,Issue: 4,Page: 296-302
Authors:  Lin-hu Ye;  Bing-xin Xiao;  Fang-rui Cao;  Ying Zheng;  Rui-le Pan;  Qi Chang
Favorite  |  View/Download:10/0  |  Submit date:2020/04/08
Epimedium L.  Icaritin  Lc-ms/ms  Metabolites  
A novel prostate cancer therapeutic strategy using icaritin-activated arylhydrocarbon-receptor to co-target androgen receptor and its splice variants Journal article
Carcinogenesis, 2015,Volume: 36,Issue: 7,Page: 757-768
Authors:  Sun F.;  Indran I.R.;  Zhang Z.W.;  Tan M.H.E.;  Li Y.;  Lim Z.L.R.;  Hua R.;  Yang C.;  Soon F.-F.;  Li J.;  Xu H.E.;  Cheung E.;  Yong E.-L.
Favorite  |  View/Download:3/0  |  Submit date:2018/12/17
Icaritin protects against oxidative stress-induced injury in cardiac H9c2 cells via Akt/Nrf2/HO-1 and calcium signalling pathways Journal article
Journal of Functional Foods, 2015,Volume: 18,Page: 213-223
Authors:  Lei S.W.;  Cui G.;  Leung G.P.H.;  Luk S.C.W.;  Hoi M.P.M.;  Wang L.;  Mahady G.B.;  Lee S.M.Y.
Favorite  |  View/Download:6/0  |  Submit date:2018/11/06
Calcium ion  Cardiac H9c2 cells  Icaritin  NF-E2-related factor 2  Oxidative stress  
Zebrafish as a new model for drug metabolism and high content screen of natural product Conference paper
PLANTA MEDICA, Guimaraes, PORTUGAL, AUG 31-SEP 04, 2014
Authors:  Lee, SMY;  Hoi, PM;  Yan, R;  Wang, YQ;  Han, YF;  Chu, IK
Favorite  |  View/Download:6/0  |  Submit date:2020/03/26
Drug Metabolism  Chinese Medicine  Zebrafish  Neurodegeneration  Vascular Disease  
Zebrafish as a new model for drug metabolism and high content screen of natural product Journal article
PLANTA MEDICA, 2014,Volume: 80,Issue: 16
Authors:  Lee, SMY;  Hoi, PM;  Yan, R;  Wang, YQ;  Han, YF;  Chu, IK
Favorite  |  View/Download:5/0  |  Submit date:2020/03/26
Neurodegeneration  Chinese Medicine  Zebrafish  Drug Metabolism  Vascular Disease  
A strategy for the improvement of the bioavailability and antiosteoporosis activity of BCS IV flavonoid glycosides through the formulation of their lipophilic aglycone into nanocrystals Journal article
Molecular Pharmaceutics, 2013,Volume: 10,Issue: 7,Page: 2534-2542
Authors:  Li Y.;  Sun S.;  Chang Q.;  Zhang L.;  Wang G.;  Chen W.;  Miao X.;  Zheng Y.
Favorite  |  View/Download:8/0  |  Submit date:2018/12/28
Antisolvent-precipitation  Glycoside  Icaritin (Ict)  Nanocrystal  Oral Bioavailability  Osteoporosis  
Oral absorption and excretion of icaritin, an aglycone and also active metabolite of prenylflavonoids from the Chinese medicine Herba Epimedii in rats Journal article
Phytomedicine, 2012,Volume: 19,Issue: 11,Page: 1024-1028
Authors:  Qi Chang;  Geng-Nan Wang;  Yan Li;  Lei Zhang;  Chang You;  Ying Zheng
Favorite  |  View/Download:9/0  |  Submit date:2020/04/09
Epimedium  Icaritin  Absorption  Excretion  Pharmacokinetics  
Combined in vivo imaging and omics approaches reveal metabolism of icaritin and its glycosides in zebrafish larvae Journal article
MOLECULAR BIOSYSTEMS, 2011,Volume: 7,Issue: 7,Page: 2128-2138
Authors:  Li, ZH (Li, Zhen Hua);  Alex, D (Alex, Deepa);  Siu, SO (Siu, Shiu On);  Chu, IK (Chu, Ivan Keung);  Renn, J (Renn, Joerg);  Winkler, C (Winkler, Christoph);  Lou, S (Lou, Shaoke);  Tsui, SKW (Tsui, Stephen Kwok-Wing);  Zhao, HY (Zhao, Hai Yu);  Yan, WR (Yan, Wendy Ru);  Mahady, GB (Mahady, Gail B.);  Li, GH (Li, Guo Hui);  Kwan, YW (Kwan, Yiu Wa);  Wang, YT (Wang, Yi Tao);  Lee, SMY (Lee, Simon Ming-Yuen)
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Animal-models  Flavonoids  Quercetin  Bone  Fluorescence  Absorption  Proteome  Swim