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Signalling pathways regulating galactosaminoglycan synthesis and structure in vascular smooth muscle: Implications for lipoprotein binding and atherosclerosis
Journal article
PHARMACOLOGY & THERAPEUTICS, 2018,Volume: 187,Page: 88-97
Authors:
Afroz, Rizwana
;
Cao, Yingnan
;
Rostam, Muhamad Ashraf
;
Ta, Hang
;
Xu, Suowen
;
Zheng, Wenhua
;
Osman, Narin
;
Kamato, Danielle
;
Little, Peter J.
Favorite
|
View/Download:30/0
|
TC[WOS]:
8
TC[Scopus]:
14
|
Submit date:2018/10/30
Atherosclerosis
Proteoglycans
Galactosaminoglycans
Signalling Pathways
Flavopiridol inhibits TGF-b-stimulated biglycan synthesis by blocking linker region phosphorylation and nuclear translocation of Smad2
Journal article
Journal of Pharmacology and Experimental Therapeutics, 2018,Volume: 365,Issue: 1,Page: 156-164
Authors:
Rostam M.A.
;
Shajimoon A.
;
Kamato D.
;
Mitra P.
;
Piva T.J.
;
Getachew R.
;
Cao Y.
;
Zheng W.
;
Osman N.
;
Little P.J.
Favorite
|
View/Download:7/0
|
TC[WOS]:
11
TC[Scopus]:
15
|
Submit date:2018/12/21
Flavopiridol Inhibits TGF-beta-Stimulated Biglycan Synthesis by Blocking Linker Region Phosphorylation and Nuclear Translocation of Smad2
Journal article
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2018,Volume: 365,Issue: 1,Page: 156-164
Authors:
Rostam, Muhamad A.
;
Shajimoon, Aravindra
;
Kamato, Danielle
;
Mitra, Partha
;
Piva, Terrence J.
;
Getachew, Robel
;
Cao, Yingnan
;
Zheng, Wenhua
;
Osman, Narin
;
Little, Peter J.
Favorite
|
View/Download:21/0
|
TC[WOS]:
11
TC[Scopus]:
15
|
Submit date:2018/10/30
Ga-q proteins: molecular pharmacology and therapeutic potential
Journal article
CELLULAR AND MOLECULAR LIFE SCIENCES, 2017,Volume: 74,Issue: 8,Page: 1379-1390
Authors:
Kamato, Danielle
;
Mitra, Partha
;
Davis, Felicity
;
Osman, Narin
;
Chaplin, Rebecca
;
Cabot, Peter J.
;
Afroz, Rizwana
;
Thomas, Walter
;
Zheng, Wenhua
;
Kaur, Harveen
;
Brimble, Margaret
;
Little, Peter J.
Favorite
|
View/Download:24/0
|
TC[WOS]:
16
TC[Scopus]:
23
|
Submit date:2018/10/30
g Proteins
Isoforms
g Protein-coupled Receptors
Gpcrs
Par-1
Hyperelongation
Atherosclerosis
g Alpha q
The role of specific Smad linker region phosphorylation in TGF-beta mediated expression of glycosaminoglycan synthesizing enzymes in vascular smooth muscle
Journal article
CELLULAR SIGNALLING, 2016,Volume: 28,Issue: 8,Page: 956-966
Authors:
Muhamad A. Rostam
;
Danielle Kamato
;
Terence J. Piva
;
Wenhua Zheng
;
Peter J. Little
;
Narin Osman
Favorite
|
View/Download:10/0
|
TC[WOS]:
19
TC[Scopus]:
25
|
Submit date:2020/06/11
Transforming Growth Factor-beta
Glycosaminoglycan
Atherosclerosis
Vascular Smooth Muscle
Signalling
Smad
Multiple growth factors, but not VEGF, stimulate glycosaminoglycan hyperelongation in retinal choroidal endothelial cells
Journal article
International Journal of Biological Sciences, 2016,Volume: 12,Issue: 9,Page: 1041-1051
Authors:
Al Gwairi O.
;
Osman N.
;
Getachew R.
;
Zheng W.
;
Liang X.-L.
;
Kamato D.
;
Thach L.
;
Little P.J.
Favorite
|
View/Download:10/0
|
TC[WOS]:
3
TC[Scopus]:
3
|
Submit date:2018/12/21
Age related macular degeneration
Bruch's membrane
Growth factors
Proteoglycans
VEGF
Xyloside
Evaluation of the potential synergism of imatinib-related poly kinase inhibitors using growth factor stimulated proteoglycan synthesis as a model response
Journal article
Journal of Pharmacy and Pharmacology, 2016,Volume: 68,Issue: 3,Page: 368-378
Authors:
Bernard R.
;
Getachew R.
;
Kamato D.
;
Thach L.
;
Osman N.
;
Chan V.
;
Zheng W.
;
Little P.J.
Favorite
|
View/Download:6/0
|
TC[WOS]:
5
TC[Scopus]:
6
|
Submit date:2018/12/21
cell signalling
GAG hyperelongation
platelet derived growth factor
proteoglycan
tinibs
transforming growth factor-β
The role of specific Smad linker region phosphorylation in TGF-β mediated expression of glycosaminoglycan synthesizing enzymes in vascular smooth muscle
Journal article
Cellular Signalling, 2016,Volume: 28,Issue: 8,Page: 956
Authors:
Rostam M.A.
;
Kamato D.
;
Piva T.J.
;
Zheng W.
;
Little P.J.
;
Osman N.
Favorite
|
View/Download:6/0
|
TC[WOS]:
19
TC[Scopus]:
25
|
Submit date:2018/10/30
Atherosclerosis
Glycosaminoglycan
Signalling
Smad
Transforming growth factor-β
Vascular smooth muscle
Platelet-derived growth factor-stimulated versican synthesis but not glycosaminoglycan elongation in vascular smooth muscle is mediated via akt phosphorylation
Journal article
Cellular Signalling, 2014,Volume: 26,Issue: 5,Page: 912-916
Authors:
Osman N.
;
Getachew R.
;
Thach L.
;
Wang H.
;
Su X.
;
Zheng W.
;
Little P.J.
Favorite
|
View/Download:8/0
|
TC[WOS]:
8
TC[Scopus]:
8
|
Submit date:2018/12/21
Akt
Atherosclerosis
GAG hyperelongation
Platelet-derived growth factor
Proteoglycans
(S)-[6]-Gingerol inhibits TGF-β-stimulated biglycan synthesis but not glycosaminoglycan hyperelongation in human vascular smooth muscle cells
Journal article
Journal of Pharmacy and Pharmacology, 2013,Volume: 65,Issue: 7,Page: 1026-1036
Authors:
Kamato D.
;
Babaahmadi Rezaei H.
;
Getachew R.
;
Thach L.
;
Guidone D.
;
Osman N.
;
Roufogalis B.
;
Duke C.C.
;
Tran V.H.
;
Zheng W.
;
Little P.J.
Favorite
|
View/Download:7/0
|
TC[WOS]:
18
TC[Scopus]:
22
|
Submit date:2018/12/21
(S)-[6]-Gingerol
biglycan
proteoglycans
Smad signalling