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Signalling pathways regulating galactosaminoglycan synthesis and structure in vascular smooth muscle: Implications for lipoprotein binding and atherosclerosis Journal article
PHARMACOLOGY & THERAPEUTICS, 2018,Volume: 187,Page: 88-97
作者:  Afroz, Rizwana;  Cao, Yingnan;  Rostam, Muhamad Ashraf;  Ta, Hang;  Xu, Suowen;  Zheng, Wenhua;  Osman, Narin;  Kamato, Danielle;  Little, Peter J.
收藏  |  浏览/下载:14/0  |  提交时间:2018/10/30
Atherosclerosis  Proteoglycans  Galactosaminoglycans  Signalling Pathways  
Flavopiridol inhibits TGF-b-stimulated biglycan synthesis by blocking linker region phosphorylation and nuclear translocation of Smad2 Journal article
Journal of Pharmacology and Experimental Therapeutics, 2018,Volume: 365,Issue: 1,Page: 156-164
作者:  Rostam M.A.;  Shajimoon A.;  Kamato D.;  Mitra P.;  Piva T.J.;  Getachew R.;  Cao Y.;  Zheng W.;  Osman N.;  Little P.J.
收藏  |  浏览/下载:2/0  |  提交时间:2018/12/21
Flavopiridol Inhibits TGF-beta-Stimulated Biglycan Synthesis by Blocking Linker Region Phosphorylation and Nuclear Translocation of Smad2 Journal article
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2018,Volume: 365,Issue: 1,Page: 156-164
作者:  Rostam, Muhamad A.;  Shajimoon, Aravindra;  Kamato, Danielle;  Mitra, Partha;  Piva, Terrence J.;  Getachew, Robel;  Cao, Yingnan;  Zheng, Wenhua;  Osman, Narin;  Little, Peter J.
收藏  |  浏览/下载:9/0  |  提交时间:2018/10/30
Ga-q proteins: molecular pharmacology and therapeutic potential Journal article
CELLULAR AND MOLECULAR LIFE SCIENCES, 2017,Volume: 74,Issue: 8,Page: 1379-1390
作者:  Kamato, Danielle;  Mitra, Partha;  Davis, Felicity;  Osman, Narin;  Chaplin, Rebecca;  Cabot, Peter J.;  Afroz, Rizwana;  Thomas, Walter;  Zheng, Wenhua;  Kaur, Harveen;  Brimble, Margaret;  Little, Peter J.
收藏  |  浏览/下载:14/0  |  提交时间:2018/10/30
g Proteins  Isoforms  g Protein-coupled Receptors  Gpcrs  Par-1  Hyperelongation  Atherosclerosis  g Alpha q  
Multiple growth factors, but not VEGF, stimulate glycosaminoglycan hyperelongation in retinal choroidal endothelial cells Journal article
International Journal of Biological Sciences, 2016,Volume: 12,Issue: 9,Page: 1041-1051
作者:  Al Gwairi O.;  Osman N.;  Getachew R.;  Zheng W.;  Liang X.-L.;  Kamato D.;  Thach L.;  Little P.J.
收藏  |  浏览/下载:5/0  |  提交时间:2018/12/21
Age related macular degeneration  Bruch's membrane  Growth factors  Proteoglycans  VEGF  Xyloside  
Evaluation of the potential synergism of imatinib-related poly kinase inhibitors using growth factor stimulated proteoglycan synthesis as a model response Journal article
Journal of Pharmacy and Pharmacology, 2016,Volume: 68,Issue: 3,Page: 368-378
作者:  Bernard R.;  Getachew R.;  Kamato D.;  Thach L.;  Osman N.;  Chan V.;  Zheng W.;  Little P.J.
收藏  |  浏览/下载:1/0  |  提交时间:2018/12/21
cell signalling  GAG hyperelongation  platelet derived growth factor  proteoglycan  tinibs  transforming growth factor-β  
The role of specific Smad linker region phosphorylation in TGF-β mediated expression of glycosaminoglycan synthesizing enzymes in vascular smooth muscle Journal article
Cellular Signalling, 2016,Volume: 28,Issue: 8,Page: 956
作者:  Rostam M.A.;  Kamato D.;  Piva T.J.;  Zheng W.;  Little P.J.;  Osman N.
收藏  |  浏览/下载:1/0  |  提交时间:2018/10/30
Atherosclerosis  Glycosaminoglycan  Signalling  Smad  Transforming growth factor-β  Vascular smooth muscle  
Platelet-derived growth factor-stimulated versican synthesis but not glycosaminoglycan elongation in vascular smooth muscle is mediated via akt phosphorylation Journal article
Cellular Signalling, 2014,Volume: 26,Issue: 5,Page: 912-916
作者:  Osman N.;  Getachew R.;  Thach L.;  Wang H.;  Su X.;  Zheng W.;  Little P.J.
收藏  |  浏览/下载:1/0  |  提交时间:2018/12/21
Akt  Atherosclerosis  GAG hyperelongation  Platelet-derived growth factor  Proteoglycans  
Suramin inhibits PDGF-stimulated receptor phosphorylation, proteoglycan synthesis and glycosaminoglycan hyperelongation in human vascular smooth muscle cells Journal article
Journal of Pharmacy and Pharmacology, 2013,Volume: 65,Issue: 7,Page: 1055-1063
作者:  Little P.J.;  Rostam M.A.;  Piva T.J.;  Getachew R.;  Kamato D.;  Guidone D.;  Ballinger M.L.;  Zheng W.;  Osman N.
收藏  |  浏览/下载:2/0  |  提交时间:2018/12/21
atherosclerosis  biglycan  imatinib  PDGFβ receptor kinase activity  PDGFβ receptor phosphorylation  
(S)-[6]-Gingerol inhibits TGF-β-stimulated biglycan synthesis but not glycosaminoglycan hyperelongation in human vascular smooth muscle cells Journal article
Journal of Pharmacy and Pharmacology, 2013,Volume: 65,Issue: 7,Page: 1026-1036
作者:  Kamato D.;  Babaahmadi Rezaei H.;  Getachew R.;  Thach L.;  Guidone D.;  Osman N.;  Roufogalis B.;  Duke C.C.;  Tran V.H.;  Zheng W.;  Little P.J.
收藏  |  浏览/下载:1/0  |  提交时间:2018/12/21
(S)-[6]-Gingerol  biglycan  proteoglycans  Smad signalling