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1,8-Cineole Ameliorates LPS-Induced Vascular Endothelium Dysfunction in Mice via PPAR-gamma Dependent Regulation of NF-kappa B Journal article
FRONTIERS IN PHARMACOLOGY, 2019,Volume: 10
Authors:  Ke-Gang Linghu;  Guo-Ping Wu;  Ling-Yun Fu;  Hong Yang;  Hai-Zhi Li;  Yan Chen;  Hua Yu;  Ling Tao;  Xiang-Chun Shen
Favorite  |  View/Download:13/0  |  Submit date:2020/03/10
1,8-cineole  Human Umbilical Vein Endothelial Cell  Lipopolysaccharide  Nf-κb  Ppar-γ  
Ponatinib exerts anti-angiogenic effects in the zebrafish and human umbilical vein endothelial cells via blocking VEGFR signaling pathway Journal article
Oncotarget, 2018,Volume: 9,Issue: 62,Page: 31958-31970
Authors:  Nana Ai;  Cheong-Meng Chong.;  Weiting Chen;  Zhe Hu;  Huanxing Su;  Guokai Chen;  Queenie Wing Lei Wong;  Wei Ge
Favorite  |  View/Download:13/0  |  Submit date:2018/12/11
Angiogenesis  Enos  Huvec  Mapk  Ponatinib  
A novel Ca2+ current blocker promotes angiogenesis and cardiac healing after experimental myocardial infarction in mice Journal article
PHARMACOLOGICAL RESEARCH, 2018,Volume: 134,Page: 109-117
Authors:  Cui, Guozhen;  Xin, Qiqi;  Tseng, Hisa Hui Ling;  Hoi, Maggie PuiMan;  Wang, Yan;  Yang, Binrui;  Choi, InLeng;  Wang, Yuqiang;  Yuan, Rong;  Chen, Keji;  Cong, Weihong;  Lee, Simon MingYuen
View  |  Adobe PDF(3018Kb)  |  Favorite  |  View/Download:285/12  |  Submit date:2018/10/30
Cardioprotection  Angiogenesis  ADTM  Zebrafish  VEGF  
A novel Ca2+ current blocker promotes angiogenesis and cardiac healing after experimental myocardial infarction in mice Journal article
PHARMACOLOGICAL RESEARCH, 2018,Volume: 134,Page: 109-117
Authors:  Guozhen Cui;  Qiqi Xin;  Hisa Hui Ling Tseng;  Maggie PuiMan Hoi;  Yan Wang;  Binrui Yang;  InLeng Choi;  Yuqiang Wang;  Rong Yuan;  Keji Chen;  Weihong Cong;  Simon MingYuen Lee
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Cardioprotection  Angiogenesis  Adtm  Zebrafish  Vegf  
Paeoniflorin Promotes Angiogenesis in A Vascular Insufficiency Model of Zebrafish in vivo and in Human Umbilical Vein Endothelial Cells in vitro Journal article
CHINESE JOURNAL OF INTEGRATIVE MEDICINE, 2018,Volume: 24,Issue: 7,Page: 494-501
Authors:  Xin Qi-qi;  Yang Bin-rui;  Zhou He-feng;  Wang Yan;  Yi Bo-wen;  Cong Wei-hong;  Lee, Simon Ming-Yuen;  Chen Ke-ji
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angiogenesis  paeoniflflorin  zebrafifish  human umbilical vein endothelial cell  
Sodium tanshinone IIA sulfonate promotes endothelial integrity via regulating VE-cadherin dynamics and RhoA/ROCK-mediated cellular contractility and prevents atorvastatin-induced intracerebral hemorrhage in zebrafish Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018,Volume: 350,Page: 32-42
Authors:  Zhou, Zhong-Yan;  Huang, Bin;  Li, Shang;  Huang, Xiao-Hui;  Tang, Jing-Yi;  Kwan, Yiu Wa;  Hoi, Pui Man;  Lee, Simon Ming-Yuen
Favorite  |  View/Download:21/0  |  Submit date:2018/10/30
Sodium Tanshinone Iia Sulfonate  Salvia Miltiorrhiza  Hemorrhagic Stroke  Atorvastatin  Rock  
Ursolic Acid Attenuates Atherosclerosis in ApoE(-/-) Mice: Role of LOX-1 Mediated by ROS/NF-B Pathway Journal article
MOLECULES, 2018,Volume: 23,Issue: 5
Authors:  Li, Qiu;  Zhao, Wenwen;  Zeng, Xi;  Hao, Zhihui
Favorite  |  View/Download:13/0  |  Submit date:2018/10/30
atherosclerosis  ROS  HUVECs  LOX-1  
Tanshinone I prevents atorvastatin-induced cerebral hemorrhage in zebrafish and stabilizes endothelial cell-cell adhesion by inhibiting. VE-cadherin internalization and actin-myosin contractility Journal article
PHARMACOLOGICAL RESEARCH, 2018,Volume: 128,Page: 389-398
Authors:  Huang, Bin;  Zhou, Zhong-Yan;  Li, Shang;  Huang, Xiao-Hui;  Tang, Jing-Yi;  Hoi, Maggie Pui Man;  Lee, Simon Ming Yuen
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Tanshinone I  Vascular integrity  Endothelial cell adhesion  Hemorrhagic stroke  Zebrafish  HUVECs  
Tanshinone I prevents atorvastatin-induced cerebral hemorrhage in zebrafish and stabilizes endothelial cell–cell adhesion by inhibiting VE-cadherin internalization and actin-myosin contractility Journal article
Pharmacological Research, 2018,Volume: 128,Page: 389-398
Authors:  Huang B.;  Zhou Z.-Y.;  Li S.;  Huang X.-H.;  Tang J.-Y.;  Hoi M.P.M.;  Lee S.M.Y.
Favorite  |  View/Download:5/0  |  Submit date:2018/11/06
Endothelial cell adhesion  Hemorrhagic stroke  HUVECs  Tanshinone I  Vascular integrity  Zebrafish  
pH-sensitive polymeric nanoparticles for co-delivery of doxorubicin and curcumin to treat cancer via enhanced pro-apoptotic and anti-angiogenic activities Journal article
ACTA BIOMATERIALIA, 2017,Volume: 58,Page: 349-364
Authors:  Zhang, Jinming;  Li, Jingjing;  Shi, Zhi;  Yang, Yang;  Xie, Xi;  Lee, Simon MingYuen;  Wang, Yitao;  Leong, Kam W.;  Chen, Meiwan
Favorite  |  View/Download:18/0  |  Submit date:2018/10/30
Anticancer  Ph-sensitive Nanoparticle  Apoptosis  Anti-angiogenesis  Co-delivery