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Effects of dextran sulfate sodium induced experimental colitis on cytochrome P450 activities in rat liver, kidney and intestine Journal article
CHEMICO-BIOLOGICAL INTERACTIONS, 2017,Volume: 271,Page: 48-58
Authors:  Hu, Nan;  Huang, Yanjuan;  Gao, Xuejiao;  Li, Sai;  Yan, Zhixiang;  Wei, Bin;  Yan, Ru
Favorite  |  View/Download:17/0  |  Submit date:2018/10/30
Experimental Colitis  Dextran Sulfate Sodium  Cyps  Rat Liver Microsomes  Rat Renal Microsomes  Rat Intestinal Microsomes  
Integrated work-flow for quantitative metabolome profiling of plants, Peucedani Radix as a case Journal article
ANALYTICA CHIMICA ACTA, 2017,Volume: 953,Page: 40-47
Authors:  Song, Yuelin;  Song, Qingqing;  Liu, Yao;  Li, Jun;  Wan, Jian-Bo;  Wang, Yitao;  Jiang, Yong;  Tu, Pengfei
View  |  Adobe PDF(782Kb)  |  Favorite  |  View/Download:314/16  |  Submit date:2018/10/30
Quantitative Metabolome  Integrated Work-flow  Offline Two Dimensional Liquid  Chromatography  Linear Range  Peucedani Radix  Isomer  
Regioselective glucuronidation of the isoflavone calycosin by human liver microsomes and recombinant human UDP-glucuronosyltransferases Journal article
Chemico-Biological Interactions, 2014,Volume: 220,Page: 231-240
Authors:  Ruan J.-Q.;  Yan R.
Favorite  |  View/Download:5/0  |  Submit date:2018/12/28
Calycosin  Glucuronidation  Metabolism  Regioselectivity  Udp-glucuronosyltransferases  
Metabolic characterization of (±)-praeruptorin A in vitro and in vivo by high performance liquid chromatography coupled with hybrid triple quadrupole-linear ion trap mass spectrometry and time-of-flight mass spectrometry Journal article
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2014,Volume: 90,Issue: 5,Page: 98-110
Authors:  Song, Yue-Lin;  Jing, Wang-Hui;  Yan, Ru;  Wang, Yi-Tao
View  |  Adobe PDF(3404Kb)  |  Favorite  |  View/Download:240/8  |  Submit date:2018/11/01
(+/-)-praeruptorin a  Metabolism  Lightsight (Tm) Software  In Vivo  Peucedani Radix  
Simultaneously enantiospecific determination of (+)-trans-khellactone, (+/-)-praeruptorin A, (+/-)-praeruptorin B, (+)-praeruptorin E, and their metabolites, (+/-)-cis-khellactone, in rat plasma using Journal article
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2014,Volume: 88,Issue: 1,Page: 269-277
Authors:  Song, Yuelin;  Jing, Wanghui;  Yang, Fengqing;  Shi, Zhan;  Yao, Meicun;  Yan, Ru;  Wang, Yitao
View  |  Adobe PDF(488Kb)  |  Favorite  |  View/Download:310/41  |  Submit date:2018/11/01
Online Spe  Chiral Lc-ms/ms  Enantiospecific  Peucedani Radix  Pharmacokinetics  
In vitro glucuronidation of five rhubarb anthraquinones by intestinal and liver microsomes from humans and rats Journal article
Chemico-Biological Interactions, 2014,Volume: 219,Page: 18
Authors:  Wu W.;  Hu N.;  Zhang Q.;  Li Y.;  Li P.;  Yan R.;  Wang Y.
Favorite  |  View/Download:3/0  |  Submit date:2018/10/31
Anthraquinones  Glucuronidation  Regioselectivity  Rhubarb  Ugts  
Characterization of in vitro and in vivo metabolites of carnosic acid, a natural antioxidant, by high performance liquid chromatography coupled with tandem mass spectrometry Journal article
Journal of Pharmaceutical and Biomedical Analysis, 2014,Volume: 89,Page: 183-196
Authors:  Song Y.;  Yan H.;  Chen J.;  Wang Y.;  Jiang Y.;  Tu P.
Favorite  |  View/Download:7/0  |  Submit date:2018/10/31
Carnosic Acid  In Vitro  In Vivo  Lc-ms/ms  Metabolism  
Regioselective glucuronidation of oxyresveratrol, a natural hydroxystilbene, by human liver and intestinal microsomes and recombinant ugts Journal article
Drug Metabolism and Pharmacokinetics, 2014,Volume: 29,Issue: 3,Page: 229
Authors:  Hu N.;  Mei M.;  Ruan J.;  Wu W.;  Wang Y.;  Yan R.
Favorite  |  View/Download:3/0  |  Submit date:2018/10/31
Glucuronidation  Kinetics  Oxyresveratrol  Oxyresveratrol-2-o-β-d-glucuronosyl  Regioselectivity  Ugt1a9  Uridine Diphospho-glucuronosyltransferase (Ugts)  
Comparative metabolism and stability of andrographolide in liver microsomes from humans, dogs and rats using ultra-performance liquid chromatography coupled with triple-quadrupole and Fourier transfor Journal article
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2013,Volume: 27,Issue: 12,Page: 1385-1392
Authors:  Zhao, Hai-Yu;  Hu, Hao;  Wang, Yi-Tao
Favorite  |  View/Download:6/0  |  Submit date:2018/11/01
Identification of cytochrome P450 isoenzymes involved in metabolism of (+)-praeruptorin A, a calcium channel blocker, by human liver microsomes using ultra high-performance liquid chromatography coupl Journal article
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2013,Volume: 77,Page: 175-188
Authors:  Jing, Wang-Hui;  Song, Yue-Lin;  Yan, Ru;  Wang, Yi-Tao
Favorite  |  View/Download:14/0  |  Submit date:2018/11/01
Angular-type Pyranocoumarins  (+)-praeruptorin a  Uhplc-qt-ms/ms  Human Liver Microsomes  Cyp 3a4