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Identification of a Wells-Dawson polyoxometalate-based AP-2 gamma inhibitor with pro-apoptotic activity Journal article
BIOCHEMICAL JOURNAL, 2018,Volume: 475,Issue: 11,Page: 1965-1977
Authors:  Hu, Jiamiao;  Tan, Si Kee;  Lim, Michelle Gek Liang;  Chang, Shie Hong;  Cui, Guimei;  Liu, Shanshan;  Narasimhan, Kamesh;  New, Siu Yee;  Wang, Xuecong;  Chen, Congling;  Chakravarty, Harapriya;  Kolatkar, Prasanna R.;  Tam, Kin Yip;  Lu, Qian;  Su, Xiaodi;  Jauch, Ralf;  Cheung, Edwin
Favorite | View/Download:33/0 | TC[WOS]:2 TC[Scopus]:3 | Submit date:2018/10/30
Ap-2γ  Breast Cancer  Fluorescent Anisotropic  Polyoxometalate  
Identification of a Wells-Dawson polyoxometalatebased AP-2γ inhibitor with pro-apoptotic activity Journal article
Biochemical Journal, 2018,Volume: 475,Issue: 11,Page: 1965-1977
Authors:  Hu J.;  Tan S.K.;  Lim M.G.L.;  Chang S.H.;  Cui G.;  Liu S.;  Narasimhan K.;  New S.Y.;  Wang X.;  Chen C.;  Chakravarty H.;  Kolatkar P.R.;  Tam K.Y.;  Lu Q.;  Su X.;  Jauch R.;  Cheung E.
Favorite | View/Download:8/0 | TC[WOS]:2 TC[Scopus]:3 | Submit date:2018/12/17
First quantitative high-throughput screen in zebrafish identifies novel pathways for increasing pancreatic β-cell mass Journal article
eLife, 2015,Volume: 4,Issue: 2015-07-01
Authors:  Wang G.;  Rajpurohit S.K.;  Delaspre F.;  Walker S.L.;  White D.T.;  Ceasrine A.;  Kuruvilla R.;  Li R.-J.;  Shim J.S.;  Liu J.O.;  Parsons M.J.;  Mumm J.S.
Favorite | View/Download:14/0 | TC[WOS]:31 TC[Scopus]:54 | Submit date:2018/10/30
Drug repurposing screen identifies lestaurtinib amplifies the ability of the poly (ADP-ribose) polymerase 1 inhibitor AG14361 to kill breast cancer associated gene-1 mutant and wild type breast cancer cells Journal article
Breast Cancer Research, 2014,Volume: 16,Issue: 3
Authors:  Vazquez-Ortiz G.;  Chisholm C.;  Xu X.;  Lahusen T.J.;  Li C.;  Sakamuru S.;  Huang R.;  Thomas C.J.;  Xia M.;  Deng C.
Favorite | View/Download:17/0 | TC[WOS]:11 TC[Scopus]:12 | Submit date:2018/12/13
Identification of marine neuroactive molecules in behaviour-based screens in the larval zebrafish Journal article
Marine Drugs, 2014,Volume: 12,Issue: 6,Page: 3307-3322
Authors:  Long S.-M.;  Liang F.-Y.;  Wu Q.;  Lu X.-L.;  Yao X.-L.;  Li S.-C.;  Li J.;  Su H.;  Pang J.-Y.;  Pei Z.
Favorite | View/Download:12/0 | TC[WOS]:11 TC[Scopus]:13 | Submit date:2018/12/28
Behavior-based Screen  C-fos  Ptz  Zebrafish  
Multi-Target Drugs: The Trend of Drug Research and Development Journal article
PLOS ONE, 2012,Volume: 7,Issue: 6,Page: 30-46
Authors:  Lu, JJ (Lu, Jin-Jian);  Pan, W (Pan, Wei);  Hu, YJ (Hu, Yuan-Jia);  Wang, YT (Wang, Yi-Tao
View | Adobe PDF | Favorite | View/Download:517/44 | TC[WOS]:138 TC[Scopus]:175 | Submit date:2018/11/01
Cancer-therapy  Alzheimers-disease  Parkinsons-disease  Attractive Target  Natural-products  b Inhibitors  Discovery  Atherosclerosis  Acetylcholinesterase  Proliferation  
A genome-wide siRNA screen to identify modulators of insulin sensitivity and gluconeogenesis Journal article
PLoS ONE, 2012,Volume: 7,Issue: 5
Authors:  Yang R.;  Lacson R.G.;  Castriota G.;  Zhang X.D.;  Liu Y.;  Zhao W.;  Einstein M.;  Camargo L.M.;  Qureshi S.;  Wong K.K.;  Zhang B.B.;  Ferrer M.;  Berger J.P.
Favorite | View/Download:12/0 | TC[WOS]:2 TC[Scopus]:2 | Submit date:2019/01/03
A high throughput screen to identify inhibitors of ATP homeostasis in non-replicating Mycobacterium tuberculosis Journal article
ACS CHEMICAL BIOLOGY, 2012,Volume: 7,Issue: 7,Page: 1190-1197
Authors:  Puiying A. Mak;  Srinivasa P. S. Rao;  Mai Ping Tan;  Xiuhua Lin;  Jason Chyba;  Joann Tay;  Seow Hwee Ng;  Bee Huat Tan;  Joseph Cherian;  Jeyaraj Duraiswamy;  Pablo Bifani;  Vivian Lim;  Boon Heng Lee;  Ngai Ling Ma;  David Beer;  Pamela Thayalan;  Kelli Kuhen;  Arnab Chatterjee;  Frantisek Supek;  Richard Glynne;  Jun Zheng;  Helena I. Boshoff;  Clifton E. Barry, 3rd;  Thomas Dick;  Kevin Pethe;  Luis R. Camacho
Favorite | View/Download:6/0 | TC[WOS]:87 TC[Scopus]:93 | Submit date:2019/01/19
From Omics to Drug Metabolism and High Content Screen of Natural Product in Zebrafish: A New Model for Discovery of Neuroactive Compound Journal article
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2012
Authors:  Ming Wai Hung;  Zai Jun Zhang;  Shang Li;  Benson Lei;  Shuai Yuan;  Guo Zhen Cui;  Pui Man Hoi;  Kelvin Chan;  Simon Ming Yuen Lee
Favorite | View/Download:9/0 | TC[WOS]:30 TC[Scopus]:34 | Submit date:2020/04/15
A novel two-stage, transdisciplinary study identifies digoxin as a possible drug for prostate cancer treatment Journal article
Cancer Discovery, 2011,Volume: 1,Issue: 1,Page: 68-77
Authors:  Platz E.A.;  Yegnasubramanian S.;  Liu J.O.;  Chong C.R.;  Shim J.S.;  Kenfield S.A.;  Stampfer M.J.;  Willett W.C.;  Giovannucci E.;  Nelson W.G.
Favorite | View/Download:5/0 | TC[WOS]:102 TC[Scopus]:116 | Submit date:2019/01/15