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Combinatorial mutagenesis en masse optimizes the genome editing activities of SpCas9 Journal article
NATURE METHODS, 2019,Volume: 16,Issue: 8,Page: 722–730
Authors:  Gigi C. G. Choi;  Peng Zhou;  Chaya T. L. Yuen;  Becky K. C. Chan;  Feng Xu;  Siyu Bao;  Hoi Yee Chu;  Dawn Thean;  Kaeling Tan;  Koon Ho Wong;  Zongli Zheng;  Alan S. L. Wong
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A chromosome‐level genome of black rockfish, Sebastes schlegelii, provides insights into the evolution of live birth Journal article
MOLECULAR ECOLOGY RESOURCES, 2019,Volume: 19,Issue: 5
Authors:  Yan He;  Yue Chang;  Lisui Bao;  Mengjun Yu;  Rui Li;  Jingjing Niu;  Guangyi Fan;  Weihao Song;  Inge Seim;  Yating Qin;  Xuemei Li;  Jinxiang Liu;  Xiangfu Kong;  Meiting Peng;  Minmin Sun;  Mengya Wang;  Jiangbo Qu;  Xuangang Wang;  Xiaobing Liu;  Xiaolong Wu;  Xi Zhao;  Xuliang Wang;  Yaolei Zhang;  Jiao Guo;  Yang Liu;  Kaiqiang Liu;  Yilin Wang;  He Zhang;  Longqi Liu;  Mingyue Wang;  Haiyang Yu;  Xubo Wang;  Jie Cheng;  Zhigang Wang;  Xun Xu;  Jian Wang;  Huanming Yang;  Simon Ming‐Yuen Lee;  Xin Liu;  Quanqi Zhang;  Jie Qi
Favorite  |  View/Download:227/0  |  Submit date:2020/01/16
Astacin Metalloproteinase  Atac‐seq  Evolution  Rockfish Genome  Viviparity  Zona Pellucida  
Advanced liquid chromatography-mass spectrometry enables merging widely targeted metabolomics and proteomics Journal article
ANALYTICA CHIMICA ACTA, 2019,Volume: 1069,Page: 89-97
Authors:  Wenjing Liu;  Qingqing Song;  Yan Cao;  Yanan Zhao;  Huixia Huo;  Yitao Wang;  Yuelin Song;  Jun Li;  Pengfei Tu
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Serially Coupled Reversed Phase Liquid  Chromatography And Hydrophilic Interaction  Liquid Chromatography  Standard Compound-free Mass  Spectrometric Parameter Optimization  Quasi-content  Tryptic Peptide  Widely Targeted Bi-omics  
Serially coupled reversed phase-hydrophilic interaction liquid chromatography-tailored multiple reaction monitoring, a fit-for-purpose tool for large-scale targeted metabolomics of medicinal bile Journal article
ANALYTICA CHIMICA ACTA, 2018,Volume: 1037,Page: 119-129
Authors:  Song, Qingqing;  Liu, Wenjing;  Chen, Xiaojia;  Li, Jun;  Li, Peng;  Yang, Fengqing;  Wang, Yitao;  Song, Yuelin;  Tu, Pengfei
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Large-scale Targeted Metabolomics  Serially Coupled Rplc-hilic  Tailored Multiple Reaction Monitoring  Medicinal Bile  Bile Acids  
Identification of Novel Pyruvate Dehydrogenase Kinase 1 (PDK1) Inhibitors by Kinase Activity-Based High-Throughput Screening for Anticancer Therapeutics Journal article
ACS Combinatorial Science, 2018,Volume: 20,Issue: 11,Page: 660-671
Authors:  Zhang W.;  Hu X.;  Chakravarty H.;  Yang Z.;  Tam K.Y.
Favorite  |  View/Download:18/0  |  Submit date:2018/12/18
cancer  high-throughput screening  pyruvate dehydrogenase kinase 1  small molecule inhibitors  Warburg effect  
Rapid identification of antimicrometastases drugs using integrated model systems with two dimensional monolayer, three dimensional spheroids, and zebrafish xenotransplantation tumors Journal article
BIOTECHNOLOGY AND BIOENGINEERING, 2018,Volume: 115,Issue: 11,Page: 2828-2843
Authors:  Fu, Afu;  Peh, Yu Ming;  Ngan, Weida;  Wei, Na;  Luo, Kathy Qian
Favorite  |  View/Download:10/0  |  Submit date:2019/01/17
antimetastasis drug discovery  fluorescence resonance energy transfer  PI3K  AKT pathway  three dimensional tumor spheroids  zebrafish xenograft tumor model  
Neural stem cells for disease modeling and evaluation of therapeutics for Tay-Sachs disease Journal article
ORPHANET JOURNAL OF RARE DISEASES, 2018,Volume: 13
Authors:  Vu, Mylinh;  Li, Rong;  Baskfield, Amanda;  Lu, Billy;  Farkhondeh, Atena;  Gorshkov, Kirill;  Motabar, Omid;  Beers, Jeanette;  Chen, Guokai;  Zou, Jizhong;  Espejo-Mojica, Angela J.;  Rodriguez-Lopez, Alexander;  Almeciga-Diaz, Carlos J.;  Barrera, Luis A.;  Jiang, Xuntian;  Ory, Daniel S.;  Marugan, Juan J.;  Zheng, Wei
Favorite  |  View/Download:51/0  |  Submit date:2018/10/30
Tay-sachs Disease  Induced Pluripotent Stem Cells  Neural Stem Cells  Cyclodextrin  Hp Beta Cd  Delta-tocopherol  Enzyme Replacement Therapy  Hexosaminidase a  Gm2 Gangliosidosis  High Throughput Screening  Drug Discovery  
Rapid and flexible actuation of droplets via a low-adhesive and deformable magnetically functionalized membrane Journal article
JOURNAL OF MATERIALS SCIENCE, 2018,Volume: 53,Issue: 18,Page: 13253-13263
Authors:  Chen, Ge;  Gao, Yibo;  Li, Mingzhong;  Ji, Bing;  Tong, Rui;  Law, Man-Kay;  Wen, Weijia;  Zhou, Bingpu
Favorite  |  View/Download:12/0  |  Submit date:2018/10/30
Triggering of cancer cell cycle arrest by a novel scorpion venom-derived peptide-Gonearrestide Journal article
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2018,Volume: 22,Issue: 9,Page: 4460-4473
Authors:  Li, Bin;  Lyu, Peng;  Xi, Xinping;  Ge, Lilin;  Mahadevappa, Ravikiran;  Shaw, Chris;  Kwok, Hang Fai
Favorite  |  View/Download:23/0  |  Submit date:2018/10/30
Anticancer Mechanism  Binding Sites  Ms  Ms Proteome  Ngs Transcriptome  Signalling Pathways  Venom Library  
Water soluble fraction from ethanolic extract of Clausena lansium seeds alleviates obesity and insulin resistance, and changes the composition of gut microbiota in high-fat diet-fed mice Journal article
JOURNAL OF FUNCTIONAL FOODS, 2018,Volume: 47,Page: 192-199
Authors:  Shen, Shengnan;  Liao, Qiwen;  Huang, Li;  Li, Dan;  Zhang, Qingwen;  Wang, Yitao;  Lee, Simon Ming-Yuen;  Lin, Ligen
View  |  Adobe PDF(1563Kb)  |  Favorite  |  View/Download:737/39  |  Submit date:2018/10/30
Clausena Lansium  Fat Mass Gain  Insulin Sensitivity  Gut Microbiota  Wampee