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Sodium tanshinone IIA sulfonate promotes endothelial integrity via regulating VE-cadherin dynamics and RhoA/ROCK-mediated cellular contractility and prevents atorvastatin-induced intracerebral hemorrhage in zebrafish Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018,Volume: 350,Page: 32-42
Authors:  Zhou, Zhong-Yan;  Huang, Bin;  Li, Shang;  Huang, Xiao-Hui;  Tang, Jing-Yi;  Kwan, Yiu Wa;  Hoi, Pui Man;  Lee, Simon Ming-Yuen
Favorite | View/Download:36/0 | TC[WOS]:5 TC[Scopus]:8 | Submit date:2018/10/30
Sodium Tanshinone Iia Sulfonate  Salvia Miltiorrhiza  Hemorrhagic Stroke  Atorvastatin  Rock  
UPLC/Q-TOFMS-Based Metabolomics Approach to Reveal the Protective Role of Other Herbs in An-Gong-Niu-Huang Wan Against the Hepatorenal Toxicity of Cinnabar and Realgar Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:  Xia, Fangbo;  Li, Ao;  Chai, Yushuang;  Xiao, Xiao;  Wan, Jianbo;  Li, Peng;  Wang, Yitao
View | Adobe PDF | Favorite | View/Download:555/30 | TC[WOS]:10 TC[Scopus]:13 | Submit date:2018/10/30
An-gong-niu-huang Wan  Cinnabar  Realgar  Metabonomics  Detoxification  Inflammation  
Tanshinone I prevents atorvastatin-induced cerebral hemorrhage in zebrafish and stabilizes endothelial cell-cell adhesion by inhibiting. VE-cadherin internalization and actin-myosin contractility Journal article
PHARMACOLOGICAL RESEARCH, 2018,Volume: 128,Page: 389-398
Authors:  Huang, Bin;  Zhou, Zhong-Yan;  Li, Shang;  Huang, Xiao-Hui;  Tang, Jing-Yi;  Hoi, Maggie Pui Man;  Lee, Simon Ming Yuen
Favorite | View/Download:41/0 | TC[WOS]:2 TC[Scopus]:4 | Submit date:2018/10/30
Tanshinone i  Vascular Integrity  Endothelial Cell Adhesion  Hemorrhagic Stroke  Zebrafish  Huvecs  
Tanshinone I prevents atorvastatin-induced cerebral hemorrhage in zebrafish and stabilizes endothelial cell–cell adhesion by inhibiting VE-cadherin internalization and actin-myosin contractility Journal article
Pharmacological Research, 2018,Volume: 128,Page: 389-398
Authors:  Huang B.;  Zhou Z.-Y.;  Li S.;  Huang X.-H.;  Tang J.-Y.;  Hoi M.P.M.;  Lee S.M.Y.
Favorite | View/Download:8/0 | TC[WOS]:2 TC[Scopus]:4 | Submit date:2018/11/06
Endothelial cell adhesion  Hemorrhagic stroke  HUVECs  Tanshinone I  Vascular integrity  Zebrafish  
Discovery of a ROCK inhibitor, FPND, which prevents cerebral hemorrhage through maintaining vascular integrity by interference with VE-cadherin Journal article
CELL DEATH DISCOVERY, 2017,Volume: 3
Authors:  Shang Li;  Nana Ai;  Mingyun Shen;  Yuanye Dang;  Cheong-Meng Chong;  Peichen Pan;  Yiu Wa Kwan;  Shun Wan Chan;  George Pak Heng Leung;  Maggie Pui Man Hoi;  Tingjun Hou;  Simon Ming-Yuen Lee
Favorite | View/Download:248/0 | TC[WOS]:5 TC[Scopus]:8 | Submit date:2020/01/16