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Ponatinib exerts anti-angiogenic effects in the zebrafish and human umbilical vein endothelial cells via blocking VEGFR signaling pathway Journal article
Oncotarget, 2018,Volume: 9,Issue: 62,Page: 31958-31970
Authors:  Nana Ai;  Cheong-Meng Chong.;  Weiting Chen;  Zhe Hu;  Huanxing Su;  Guokai Chen;  Queenie Wing Lei Wong;  Wei Ge
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Angiogenesis  Enos  Huvec  Mapk  Ponatinib  
A novel Ca2+ current blocker promotes angiogenesis and cardiac healing after experimental myocardial infarction in mice Journal article
PHARMACOLOGICAL RESEARCH, 2018,Volume: 134,Page: 109-117
Authors:  Cui, Guozhen;  Xin, Qiqi;  Tseng, Hisa Hui Ling;  Hoi, Maggie PuiMan;  Wang, Yan;  Yang, Binrui;  Choi, InLeng;  Wang, Yuqiang;  Yuan, Rong;  Chen, Keji;  Cong, Weihong;  Lee, Simon MingYuen
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Cardioprotection  Angiogenesis  ADTM  Zebrafish  VEGF  
Paeoniflorin Promotes Angiogenesis in A Vascular Insufficiency Model of Zebrafish in vivo and in Human Umbilical Vein Endothelial Cells in vitro Journal article
CHINESE JOURNAL OF INTEGRATIVE MEDICINE, 2018,Volume: 24,Issue: 7,Page: 494-501
Authors:  Xin Qi-qi;  Yang Bin-rui;  Zhou He-feng;  Wang Yan;  Yi Bo-wen;  Cong Wei-hong;  Lee, Simon Ming-Yuen;  Chen Ke-ji
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angiogenesis  paeoniflflorin  zebrafifish  human umbilical vein endothelial cell  
Sodium tanshinone IIA sulfonate promotes endothelial integrity via regulating VE-cadherin dynamics and RhoA/ROCK-mediated cellular contractility and prevents atorvastatin-induced intracerebral hemorrhage in zebrafish Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018,Volume: 350,Page: 32-42
Authors:  Zhou, Zhong-Yan;  Huang, Bin;  Li, Shang;  Huang, Xiao-Hui;  Tang, Jing-Yi;  Kwan, Yiu Wa;  Hoi, Pui Man;  Lee, Simon Ming-Yuen
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Sodium tanshinone IIA sulfonate  Salvia miltiorrhiza  Hemorrhagic stroke  Atorvastatin  ROCK  
Ursolic Acid Attenuates Atherosclerosis in ApoE(-/-) Mice: Role of LOX-1 Mediated by ROS/NF-B Pathway Journal article
MOLECULES, 2018,Volume: 23,Issue: 5
Authors:  Li, Qiu;  Zhao, Wenwen;  Zeng, Xi;  Hao, Zhihui
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atherosclerosis  ROS  HUVECs  LOX-1  
Tanshinone I prevents atorvastatin-induced cerebral hemorrhage in zebrafish and stabilizes endothelial cell–cell adhesion by inhibiting VE-cadherin internalization and actin-myosin contractility Journal article
Pharmacological Research, 2018,Volume: 128,Page: 389-398
Authors:  Huang B.;  Zhou Z.-Y.;  Li S.;  Huang X.-H.;  Tang J.-Y.;  Hoi M.P.M.;  Lee S.M.Y.
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Endothelial cell adhesion  Hemorrhagic stroke  HUVECs  Tanshinone I  Vascular integrity  Zebrafish  
Tanshinone I prevents atorvastatin-induced cerebral hemorrhage in zebrafish and stabilizes endothelial cell-cell adhesion by inhibiting. VE-cadherin internalization and actin-myosin contractility Journal article
PHARMACOLOGICAL RESEARCH, 2018,Volume: 128,Page: 389-398
Authors:  Huang, Bin;  Zhou, Zhong-Yan;  Li, Shang;  Huang, Xiao-Hui;  Tang, Jing-Yi;  Hoi, Maggie Pui Man;  Lee, Simon Ming Yuen
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Tanshinone I  Vascular integrity  Endothelial cell adhesion  Hemorrhagic stroke  Zebrafish  HUVECs  
pH-sensitive polymeric nanoparticles for co-delivery of doxorubicin and curcumin to treat cancer via enhanced pro-apoptotic and anti-angiogenic activities Journal article
ACTA BIOMATERIALIA, 2017,Volume: 58,Page: 349-364
Authors:  Zhang, Jinming;  Li, Jingjing;  Shi, Zhi;  Yang, Yang;  Xie, Xi;  Lee, Simon MingYuen;  Wang, Yitao;  Leong, Kam W.;  Chen, Meiwan
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Anticancer  Ph-sensitive Nanoparticle  Apoptosis  Anti-angiogenesis  Co-delivery  
Spatholobi Caulis extracts promote angiogenesis in HUVECs in vitro and in zebrafish embryos in vivo via up-regulation of VEGFRs Journal article
JOURNAL OF ETHNOPHARMACOLOGY, 2017,Volume: 200,Page: 74-83
Authors:  Zhou, Zhong-Yan;  Huan, Li-Yun;  Zhao, Wai-Rong;  Tang, Nuo;  Jin, Yu;  Tang, Jing-Yi
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Spatholobi Caulis  Flavonoids  Pro-angiogenesis  Zebrafish  HUVECs  
An andrographolide derivative AGP-26b exibitiing anti-angiogenic activity in HUVECs and zebrafish via blocking the VEGFA/VEGFR2 signaling pathway Journal article
MOLECULAR BIOSYSTEMS, 2017,Volume: 13,Issue: 3,Page: 525-536
Authors:  Huang, Bin;  Peng, Yuran;  Li, Jingjing;  Li, Shang;  Sun, Yicheng;  Wang, Decai;  Yang, Binrui;  Chan, Judy Yuet-Wa;  Yu, Huidong;  Leung, George Pak-Heng;  Hoi, Maggie Pui-Man;  Zhou, Guo-Chun;  Lee, Simon Ming-Yuen
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