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Inhibiting Glycogen Synthase Kinase 3 Reverses Obesity-Induced White Adipose Tissue Inflammation by Regulating Apoptosis Inhibitor of Macrophage/CD5L-Mediated Macrophage Migration Journal article
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2018,Volume: 38,Issue: 9,Page: 2103-2116
Authors:  Wang, Li;  Wang, Yuan;  Zhang, Chao;  Li, Jingjing;  Meng, Yuan;  Dou, Man;  Noguchi, Constance Tom;  Di, Lijun
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Adipose Tissue  Gsk3  Inflammation  Macrophages  Obesity  
GSK3-activated STAT5 regulates expression of SFRPs to modulate adipogenesis Journal article
FASEB JOURNAL, 2018,Volume: 32,Issue: 9,Page: 4714-4726
Authors:  Wang, Li;  Wang, Yuan;  Meng, Yuan;  Zhang, Chao;  Di, Lijun
Favorite  |  View/Download:167/0  |  Submit date:2018/10/30
Adipocyte Differentiation  Gsk3  Wnt Pathway  
Presenilin 1 deficiency suppresses autophagy in human neural stem cells through reducing γ-secretase-independent ERK/CREB signaling Journal article
CELL DEATH & DISEASE, 2018,Volume: 9,Page: 1-13
Authors:  Cheong-Meng Chong;  Minjing Ke;  Yuan Tan;  Zhijian Huang;  Ke Zhang;  Nana Ai;  Wei Ge;  Dajiang Qin;  Jia-Hong Lu;  Huanxing Su
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Pinocembrin from Penthorum chinense Pursh suppresses hepatic stellate cells activation through a unified SIRT3-TGF-beta-Smad signaling pathway Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018,Volume: 341,Page: 38-50
Authors:  Zhou, Fayang;  Wang, Anqi;  Li, Dan;  Wang, Yitao;  Lin, Ligen
View  |  Adobe PDF(2014Kb)  |  Favorite  |  View/Download:79/6  |  Submit date:2018/10/30
Liver Fibrosis  Hepatic Stellate Cells  Penthorum Chinense Pursh  Pinocembrin  Sma- And Mad-related Proteins  Silent Mating Type Information Regulation 2 Homolog 3  
A Novel Tetramethylpyrazine Derivative Prophylactically Protects against Glutamate-Induced Excitotoxicity in Primary Neurons through the Blockage of N-Methyl-D-aspartate Receptor Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:  Hu, Shengquan;  Hu, Huihui;  Mak, Shinghung;  Cui, Guozhen;  Lee, Mingyuen;  Shan, Luchen;  Wang, Yuqiang;  Lin, Huangquan;  Zhang, Zaijun;  Han, Yifan
Favorite  |  View/Download:9/0  |  Submit date:2018/10/30
Alzheimer's disease  tetramethylpyrazine derivative  NMDA receptor  neuroprotection  oxidative stress  GSK3 beta  
Pinocembrin from Penthorum chinense Pursh suppresses hepatic stellate cells activation through a unified SIRT3-TGF-β-Smad signaling pathway Journal article
Toxicology and Applied Pharmacology, 2018,Volume: 341,Page: 38
Authors:  Zhou F.;  Wang A.;  Li D.;  Wang Y.;  Lin L.
Favorite  |  View/Download:4/0  |  Submit date:2018/10/31
Hepatic stellate cells  Liver fibrosis  Penthorum chinense Pursh  Pinocembrin  Silent mating type information regulation 2 homolog 3  Sma- and Mad-related proteins  
SLM, a novel carbazole-based fluorophore attenuates okadaic acid-induced tau hyperphosphorylation via down-regulating GSK-3 beta activity in SH-SY5Y cells Conference paper
Authors:  Wu, Xiaoli;  Kosaraju, Jayasankar;  Tam, Kin Yip
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Tau hyperphosphorylation  Alzheimer's disease  SLM  Okadaic acid  Glycogen synthase kinase-3 beta  
Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B Journal article
NEUROPHARMACOLOGY, 2017,Volume: 126,Page: 12-24
Authors:  Guo, Baojian;  Hu, Shengquan;  Zheng, Chengyou;  Wang, Hongyu;  Luo, Fangcheng;  Li, Haitao;  Cui, Wei;  Yang, Xifei;  Cui, Guozhen;  Mak, Shinghung;  Choi, Tony Chung-Lit;  Ma, Edmond Dik-Lung;  Wang, Yuqiang;  Lee, Simon Ming Yuen;  Zhang, Zaijun;  Han, Yifan
View  |  Adobe PDF(2766Kb)  |  Favorite  |  View/Download:87/4  |  Submit date:2018/10/31
Parkinson's disease  SU4312  Neuroprotection  Myocyte enhancer factor 2D  Monoamine oxidase-B  
Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B Journal article
Neuropharmacology, 2017,Volume: 126,Page: 12-24
Authors:  Guo B.;  Hu S.;  Zheng C.;  Wang H.;  Luo F.;  Li H.;  Cui W.;  Yang X.;  Cui G.;  Mak S.;  Choi T.C.-L.;  Ma E.D.-L.;  Wang Y.;  Lee S.M.Y.;  Zhang Z.;  Han Y.
Favorite  |  View/Download:3/0  |  Submit date:2018/11/06
Monoamine oxidase-B  Myocyte enhancer factor 2D  Neuroprotection  Parkinson's disease  SU4312  
Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B Journal article
Neuropharmacology, 2017,Volume: 126,Page: 12-24
Authors:  Guo B.;  Hu S.;  Zheng C.;  Wang H.;  Luo F.;  Li H.;  Cui W.;  Yang X.;  Cui G.;  Mak S.;  Choi T.C.-L.;  Ma E.D.-L.;  Wang Y.;  Lee S.M.Y.;  Zhang Z.;  Han Y.
Favorite  |  View/Download:3/0  |  Submit date:2018/11/06
Monoamine oxidase-B  Myocyte enhancer factor 2D  Neuroprotection  Parkinson's disease  SU4312