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Resveratrol ameliorates endothelial dysfunction in diabetic and obese mice through sirtuin 1 and peroxisome proliferator-activated receptor δ Journal article
Pharmacological Research, 2019,Volume: 139,Page: 384-394
作者:  Cheang W.S.;  Wong W.T.;  Wang L.;  Cheng C.K.;  Lau C.W.;  Ma R.C.W.;  Xu A.;  Wang N.;  Huang Y.;  Tian X.Y.
收藏  |  浏览/下载:4/0  |  提交时间:2019/01/15
Diet induced obesity  Endothelial dysfunction  PPARδ  SIRT1  
Anti-neuroinflammatory effects of SLOH in Aβ-induced BV-2 microglial cells and 3xTg-AD mice involve the inhibition of GSK-3β Journal article
Neuroscience Letters, 2018,Volume: 687,Page: 207-215
作者:  Wu X.;  Kosaraju J.;  Tam K.Y.
收藏  |  浏览/下载:0/0  |  提交时间:2018/12/18
3xTg-AD mice  BV-2 cells  GSK-3β  Neuroinflammation  SLOH  
Anti-neuroinflammatory effects of SLOH in A beta-induced BV-2 microglial cells and 3xTg-AD mice involve the inhibition of GSK-3 beta Journal article
NEUROSCIENCE LETTERS, 2018,Volume: 687,Page: 207-215
作者:  Wu, Xiaoli;  Kosaraju, Jayasankar;  Tam, Kin Yip
收藏  |  浏览/下载:2/0  |  提交时间:2019/01/17
SLOH  BV-2 cells  3xTg-AD mice  Neuroinflammation  GSK-3 beta  
Inhibiting Glycogen Synthase Kinase 3 Reverses Obesity-Induced White Adipose Tissue Inflammation by Regulating Apoptosis Inhibitor of Macrophage/CD5L-Mediated Macrophage Migration Journal article
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2018,Volume: 38,Issue: 9,Page: 2103-2116
作者:  Wang, Li;  Wang, Yuan;  Zhang, Chao;  Li, Jingjing;  Meng, Yuan;  Dou, Man;  Noguchi, Constance Tom;  Di, Lijun
收藏  |  浏览/下载:11/0  |  提交时间:2018/10/30
Adipose Tissue  Gsk3  Inflammation  Macrophages  Obesity  
GSK3-activated STAT5 regulates expression of SFRPs to modulate adipogenesis Journal article
FASEB JOURNAL, 2018,Volume: 32,Issue: 9,Page: 4714-4726
作者:  Wang, Li;  Wang, Yuan;  Meng, Yuan;  Zhang, Chao;  Di, Lijun
收藏  |  浏览/下载:326/0  |  提交时间:2018/10/30
Adipocyte Differentiation  Gsk3  Wnt Pathway  
Presenilin 1 deficiency suppresses autophagy in human neural stem cells through reducing γ-secretase-independent ERK/CREB signaling Journal article
CELL DEATH & DISEASE, 2018,Volume: 9,Page: 1-13
作者:  Cheong-Meng Chong;  Minjing Ke;  Yuan Tan;  Zhijian Huang;  Ke Zhang;  Nana Ai;  Wei Ge;  Dajiang Qin;  Jia-Hong Lu;  Huanxing Su
收藏  |  浏览/下载:22/0  |  提交时间:2018/10/30
Physalin B induces cell cycle arrest and triggers apoptosis in breast cancer cells through modulating p53-dependent apoptotic pathway Journal article
BIOMEDICINE & PHARMACOTHERAPY, 2018,Volume: 101,Page: 334-341
作者:  Wang, Anqi;  Wang, Shengpeng;  Zhou, Fayang;  Li, Peng;  Wang, Yitao;  Gan, Lishe;  Lin, Ligen
浏览  |  Adobe PDF(1614Kb)  |  收藏  |  浏览/下载:145/12  |  提交时间:2018/10/30
Physalin b  Breast Cancer  Cell Cycle  Apoptosis  P53  Akt  
SLOH, a carbazole-based fluorophore, mitigates neuropathology and behavioral impairment in the triple-transgenic mouse model of Alzheimer's disease Journal article
NEUROPHARMACOLOGY, 2018,Volume: 131,Page: 351-363
作者:  Wu, Xiaoli;  Kosaraju, Jayasankar;  Zhou, Wei;  Tam, Kin Yip
收藏  |  浏览/下载:8/0  |  提交时间:2018/10/31
Amyloid beta  Aggregation  Alzheimer's disease  3xTg-AD  Neuroprotection  SH-SY5Y  
Pinocembrin from Penthorum chinense Pursh suppresses hepatic stellate cells activation through a unified SIRT3-TGF-beta-Smad signaling pathway Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018,Volume: 341,Page: 38-50
作者:  Zhou, Fayang;  Wang, Anqi;  Li, Dan;  Wang, Yitao;  Lin, Ligen
浏览  |  Adobe PDF(2014Kb)  |  收藏  |  浏览/下载:141/10  |  提交时间:2018/10/30
Liver Fibrosis  Hepatic Stellate Cells  Penthorum Chinense Pursh  Pinocembrin  Sma- And Mad-related Proteins  Silent Mating Type Information Regulation 2 Homolog 3  
A Novel Tetramethylpyrazine Derivative Prophylactically Protects against Glutamate-Induced Excitotoxicity in Primary Neurons through the Blockage of N-Methyl-D-aspartate Receptor Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
作者:  Hu, Shengquan;  Hu, Huihui;  Mak, Shinghung;  Cui, Guozhen;  Lee, Mingyuen;  Shan, Luchen;  Wang, Yuqiang;  Lin, Huangquan;  Zhang, Zaijun;  Han, Yifan
收藏  |  浏览/下载:13/0  |  提交时间:2018/10/30
Alzheimer's disease  tetramethylpyrazine derivative  NMDA receptor  neuroprotection  oxidative stress  GSK3 beta