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A Novel Tetramethylpyrazine Derivative Prophylactically Protects against Glutamate-Induced Excitotoxicity in Primary Neurons through the Blockage of N-Methyl-D-aspartate Receptor Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:  Hu, Shengquan;  Hu, Huihui;  Mak, Shinghung;  Cui, Guozhen;  Lee, Mingyuen;  Shan, Luchen;  Wang, Yuqiang;  Lin, Huangquan;  Zhang, Zaijun;  Han, Yifan
Favorite | View/Download:28/0 | TC[WOS]:6 TC[Scopus]:8 | Submit date:2018/10/30
Alzheimer's disease  tetramethylpyrazine derivative  NMDA receptor  neuroprotection  oxidative stress  GSK3 beta  
H2O2 attenuates IGF-1R tyrosine phosphorylation and its survival signaling properties in neuronal cells via NR2B containing NMDA receptor Journal article
ONCOTARGET, 2017,Volume: 8,Issue: 39,Page: 65313-65328
Authors:  Zeng, Zhiwen;  Wang, Dejun;  Gaur, Uma;  Liao Rifang;  Wang, Haitao;  Zheng, Wenhua
Favorite | View/Download:17/0 | TC[WOS]:3 TC[Scopus]:4 | Submit date:2018/10/30
H2o2  Sh-sy5y  Nr2b  Nmda  Igf-1r  
Glutamate attenuates IGF-1 receptor tyrosine phosphorylation in mouse brain: Possible significance in ischemic brain damage Journal article
Neuroscience Research, 2012,Volume: 74,Issue: 3-4,Page: 290-297
Authors:  Sun C.;  Meng Q.;  Zhang L.;  Wang H.;  Quirion R.;  Zheng W.
Favorite | View/Download:3/0 | TC[WOS]:15 TC[Scopus]:15 | Submit date:2018/12/21
Brain ischemia  Glutamate  IGF-1  NMDA receptor  Tyrosine phosphorylation  
Hydrogen peroxide attenuates the prosurvival signaling of insulin-like growth factor-1 through two pathways Journal article
NeuroReport, 2012,Volume: 23,Issue: 13,Page: 768-773
Authors:  Sun C.;  Wang D.;  Zheng W.
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antioxidant  insulin-like growth factor-1  MK-801  N-methyl-D-aspartate receptors  oxidative stress  Trolox  
Glutamate acting on N-methyl-D-aspartate receptors attenuates insulin-like growth factor-1 receptor tyrosine phosphorylation and Its survival signaling properties in rat hippocampal neurons Journal article
Journal of Biological Chemistry, 2009,Volume: 284,Issue: 2,Page: 855-861
Authors:  Zheng W.-H.;  Quirion R.
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Development of a high performance liquid chromatography-tandem mass method for determination of bis(7)-tacrine, a promising anti-Alzheimer’s dimer, in rat blood Journal article
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2007,Volume: 44,Issue: 5,Page: 1133-1138
Authors:  Yu, H;  Ho, JMK;  Kan, KKW;  Cheng, BWH;  Li, WM;  Zhang, L;  Lin, G;  Pang, YP;  Gu, ZM;  Chan, K;  Wang, YT;  Han, YF
View | Adobe PDF | Favorite | View/Download:489/11 | TC[WOS]:4 TC[Scopus]:3 | Submit date:2018/11/01
Bis(7)-tacrine  Dimer  Alzheimer's Disease  Hplc-ms/ms  Drug Monitoring  Pharmacokinetics  
Identification of genes regulated by memantine and MK-801 in adult rat brain by cDNA microarray analysis Journal article
Neuropsychopharmacology, 2004,Volume: 29,Issue: 6,Page: 1070-1079
Authors:  Marvanova M.;  Lakso M.;  Wong G.
Favorite | View/Download:13/0 | TC[WOS]:29 TC[Scopus]:31 | Submit date:2018/12/18
Gene expression  Glutamate NMDA receptors  in situ hybridization  Memantine  Microarray  MK-801  
Subunit selective decrease of AMPA and metabotropic glutamate receptor mRNA expression in rat brain by systemic administration of the NMDA receptor blocker MK-801 Journal article
Journal of Molecular Neuroscience, 2003,Volume: 21,Issue: 1,Page: 29-34
Authors:  Storvik M.;  Linden A.-M.;  Lakso M.;  Wong G.
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AMPA  Excitatory  Glutamate receptor  Metabotropic  
Expression profiling to understand actions of NMDA/glutamate receptor antagonists in rat brain Journal article
Neurochemical Research, 2002,Volume: 27,Issue: 10,Page: 1209-1220
Authors:  Toronen P.;  Storvik M.;  Linden A.-M.;  Kontkanen O.;  Marvanova M.;  Lakso M.;  Castren E.;  Wong G.
Favorite | View/Download:8/0 | TC[WOS]:10 TC[Scopus]:12 | Submit date:2018/12/18
CAMP  Expressed sequence tags  Gene expression  Kuopiochip  Microarray  Neurotrophins  
Induction of cAMP response element modulator (CREM) and inducible cAMP early repressor (ICER) expression in rat brain by uncompetitive N-methyl-D- aspartate receptor antagonists Journal article
Journal of Pharmacology and Experimental Therapeutics, 2000,Volume: 294,Issue: 1,Page: 52-60
Authors:  Storvik M.;  Linden A.-M.;  Kontkanen O.;  Lakso M.;  Castren E.;  Wong G.
Favorite | View/Download:10/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2018/12/18