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Combinatorial mutagenesis en masse optimizes the genome editing activities of SpCas9 Journal article
NATURE METHODS, 2019,Volume: 16,Issue: 8,Page: 722–730
Authors:  Gigi C. G. Choi;  Peng Zhou;  Chaya T. L. Yuen;  Becky K. C. Chan;  Feng Xu;  Siyu Bao;  Hoi Yee Chu;  Dawn Thean;  Kaeling Tan;  Koon Ho Wong;  Zongli Zheng;  Alan S. L. Wong
Favorite  |  View/Download:10/0  |  Submit date:2020/05/21
Building Potent Chimeric Antigen Receptor T Cells With CRISPR Genome Editing Journal article
FRONTIERS IN IMMUNOLOGY, 2019,Volume: 10
Authors:  Jie Liu;  Guangyu Zhou;  Li Zhang;  Qi Zhao
Favorite  |  View/Download:6/0  |  Submit date:2020/05/14
Chimeric Antigen Receptor  Crispr  Gene Editing  Immunotherapy  Cancer  Car t  
Force-Sensing Robotic Microinjection System for Automated Multi-Cell Injection With Consistent Quality Journal article
IEEE ACCESS, 2019,Volume: 7,Page: 55543-55553
Authors:  Zhijie Nan;  Qingsong Xu;  Yibo Zhang;  Wei Ge
Favorite  |  View/Download:5/0  |  Submit date:2020/05/14
Microinjection  Machine Vision  Force Sensing  Microrobotics  Automation  Biomedical Engineering  
Optimizing CRISPR/Cas9 technology for precise correction of the Fgfr3-Gly374Arg mutation in achondroplasia in mice Journal article
The Journal of Biological Chemistry, 2018
Authors:  Kai Miao;  Xin Zhang;  Sek Man Su;  Jianming Zeng;  Zebin Huang;  Un In Chan;  Xiaoling Xu;  Chu-Xia Deng
Favorite  |  View/Download:23/0  |  Submit date:2018/12/17
Fgfr3  Crispr/cas9  Protein  Targeted Correction  Off-target  Achondroplasia  Dwarfism  Genome Editing  Gene Therapy  
An efficient platform for generating somatic point mutations with germline transmission in the zebrafish by CRISPR/Cas9-mediated gene editing Journal article
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018,Volume: 293,Issue: 17,Page: 6611-6622
Authors:  Yibo Zhang;  Zhiwei Zhang;  Wei Ge
Favorite  |  View/Download:29/0  |  Submit date:2018/10/30
Somatic Point Mutation  Crispr/cas9  Homology-directed Recombination (Hdr)  Knock-in  Zebrafish  
Genome editing in fishes and their applications Journal article
GENERAL AND COMPARATIVE ENDOCRINOLOGY, 2018,Volume: 257,Page: 3-12
Authors:  Zhu, Bo;  Ge, Wei
Favorite  |  View/Download:23/0  |  Submit date:2018/10/30
Genome Editing  Zfn  Talen  Crispr/cas9  Fish  Teleosts  
Functional Analysis of Nuclear Estrogen Receptors in Zebrafish Reproduction by Genome Editing Approach Journal article
ENDOCRINOLOGY, 2017,Volume: 158,Issue: 7,Page: 2292-2308
Authors:  Lu, Huijie;  Cui, Yong;  Jiang, Liwen;  Ge, Wei
Favorite  |  View/Download:19/0  |  Submit date:2018/10/30
Building a Genetic Manipulation Tool Box for Orchid Biology: Identification of Constitutive Promoters and Application of CRISPR/Cas9 in the Orchid, Dendrobium officinale Journal article
FRONTIERS IN PLANT SCIENCE, 2017,Volume: 7
Authors:  Kui, Ling;  Chen, Haitao;  Zhang, Weixiong;  He, Simei;  Xiong, Zijun;  Zhang, Yesheng;  Yan, Liang;  Zhong, Chaofang;  He, Fengmei;  Chen, Junwen;  Zeng, Peng;  Zhang, Guanghui;  Yang, Shengchao;  Dong, Yang;  Wang, Wen;  Cai, Jing
Favorite  |  View/Download:26/0  |  Submit date:2018/10/30
Dendrobium officinale  transgene  vector construction  CRISPR/Cas9 gene editing  overexpression  lignocellulose biosynthesis  gene promoters  
Recapitulating and correcting marfan syndrome in a cellular model Journal article
International Journal of Biological Sciences, 2017,Volume: 13,Issue: 5,Page: 588-603
Authors:  Park J.W.;  Yan L.;  Stoddard C.;  Wang X.;  Yue Z.;  Crandall L.;  Robinson T.;  Chang Y.;  Denton K.;  Li E.;  Jiang B.;  Zhang Z.;  Martins-Taylor K.;  Yee S.-P.;  Nie H.;  Gu F.;  Si W.;  Xie T.;  Yue L.;  Xu R.-H.
Favorite  |  View/Download:9/0  |  Submit date:2018/12/20
Disease Modeling  Genome Editing  Human Pluripotent Stem Cells  Marfan Syndrome  Osteogenesis  Smooth Muscle  
APC/C dysfunction limits excessive cancer chromosomal instability Journal article
Cancer Discovery, 2017,Volume: 7,Issue: 2
Authors:  Sansregret L;  Patterson JO;  Dewhurst S;  López-García C;  Koch A;  McGranahan N;  Chao WCH;  Barry DJ;  Rowan A;  Instrell R;  Horswell S;  Way M;  Howell M;  Singleton MR;  Medema RH;  Nurse P;  Petronczki M;  Swanton C
Favorite  |  View/Download:5/0  |  Submit date:2018/12/18