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Combined use of arginase and dichloroacetate exhibits anti-proliferative effects in triple negative breast cancer cells Journal article
JOURNAL OF PHARMACY AND PHARMACOLOGY, 2019,Volume: 71,Issue: 3,Page: 306-315
Authors:  Angela Verma;  Yau-Min Lam;  Yun-Chung Leung;  Xiaohui Hu;  Xin Chen;  Edwin Cheung;  Kin Yip Tam
Favorite  |  View/Download:12/0  |  Submit date:2020/05/21
Bacillus Caldovelox Arginase  Breast Cancer  Dichloroacetate  Drug Combination  Pegyated Human Arginase  
Astragalus Polysaccharide RAP Selectively Attenuates Paclitaxel-Induced Cytotoxicity Toward RAW 264.7 Cells by Reversing Cell Cycle Arrest and Apoptosis Journal article
FRONTIERS IN PHARMACOLOGY, 2019,Volume: 9
Authors:  Bao, WR;  Li, ZP;  Zhang, QW;  Li, LF;  Liu, HB;  Ma, DL;  Leung, CH;  Lu, AP;  Bian, Z;  Han, QB
Favorite  |  View/Download:8/0  |  Submit date:2020/03/24
Cell Cycle  Astragalus Polysaccharide  Cytotoxicity  Protective Effect  Apoptosis  
MK2 mediates macrophage activation and acute lung injury by regulating let-7e miRNA Journal article
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2018,Volume: 315,Issue: 3,Page: L371-L381
Authors:  Wu, Yaxian;  He, Huiqiong;  Ding, Yunhe;  Liu, Sirui;  Zhang, Depeng;  Wang, Jun;  Jiang, Hongchao;  Zhang, Dan;  Sun, Lei;  Ye, Richard D.;  Qian, Feng
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acute lung injury  let-7e  lipopolysaccharides  macrophage  MAPK-activated protein kinase 2  miRNA  MK2  
Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 830,Page: 17-25
Authors:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping;  Wang, Yitao;  Li, Ao;  Lin, Li-Gen;  Lu, Jin-Jian
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Nagilactone e  Non-small Cell Lung Cancer  Cyclin B1  Cell Cycle  Apoptosis  
Fast identification of anticancer constituents in Forsythiae Fructus based on metabolomics approaches Journal article
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2018,Volume: 154,Page: 312-320
Authors:  Bao, Jiaolin;  Ding, Ren-Bo;  Jia, Xuejing;  Liang, Yeer;  Liu, Fang;  Wang, Kai;  Zhang, Chao;  Li, Peng;  Wang, Yitao;  Wan, Jian-Bo;  He, Chengwei
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Forsythiae Fructus  Anticancer  Metabolomics  Multivariate Data Analysis  B16-f10 Melanoma  
Physalin B induces cell cycle arrest and triggers apoptosis in breast cancer cells through modulating p53-dependent apoptotic pathway Journal article
BIOMEDICINE & PHARMACOTHERAPY, 2018,Volume: 101,Page: 334-341
Authors:  Wang, Anqi;  Wang, Shengpeng;  Zhou, Fayang;  Li, Peng;  Wang, Yitao;  Gan, Lishe;  Lin, Ligen
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Physalin b  Breast Cancer  Cell Cycle  Apoptosis  P53  Akt  
Proanthocyanidins from Uncaria rhynchophylla induced apoptosis in MDA-MB-231 breast cancer cells while enhancing cytotoxic effects of 5-fluorouracil Journal article
FOOD AND CHEMICAL TOXICOLOGY, 2017,Volume: 107,Page: 248-260
Authors:  Chen, Xiao-Xin;  Leung, George Pak-Heng;  Zhang, Zhang-Jin;  Xiao, Jian-Bo;  Lao, Li-Xing;  Feng, Feng;  Mak, Judith Choi-Wo;  Wang, Ying;  Sze, Stephen Cho-Wing;  Zhang, Kahn Yan-Bo
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Uncaria Rhynchophylla  Proanthocyanidins  5-fluorouracil  Breast Cancer  Apoptosis  
Reversal of paclitaxel resistance in human ovarian cancer cells with redox-responsive micelles consisting of alpha-tocopheryl succinate-based polyphosphoester copolymers Journal article
ACTA PHARMACOLOGICA SINICA, 2017,Volume: 38,Issue: 6,Page: 859-873
Authors:  Chen, Feng-qian;  Zhang, Jin-ming;  Fang, Xie-fan;  Yu, Hua;  Liu, Yu-ling;  Li, Hui;  Wang, Yi-tao;  Chen, Mei-wan
Favorite  |  View/Download:14/0  |  Submit date:2018/10/30
Ovarian Carcinoma  Paclitaxel  Multidrug Resistance  Nanomedicines  D-alpha-tocopheryl Succinate  Redox-responsive Micelles  P-gp  Apoptosis  Cell Cycle Arrest  A2780/ptx Cells  
Co-delivery of paclitaxel and tetrandrine via iRGD peptide conjugated lipid-polymer hybrid nanoparticles overcome multidrug resistance in cancer cells Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Zhang, Jinming;  Wang, Lu;  Chan, Hon Fai;  Xie, Wei;  Chen, Sheng;  He, Chengwei;  Wang, Yitao;  Chen, Meiwan
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Osthole inhibited TGF beta-induced epithelial-mesenchymal transition (EMT) by suppressing NF-kappa B mediated Snail activation in lung cancer A549 cells Journal article
CELL ADHESION & MIGRATION, 2017,Volume: 11,Issue: 5-6,Page: 464-475
Authors:  Feng, Haitao;  Lu, Jin-Jian;  Wang, Yitao;  Pei, Lixia;  Chen, Xiuping
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Emt  Nf-kappa b  Osthole Snail  Tgf-beta 1