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Triggering of cancer cell cycle arrest by a novel scorpion venom-derived peptide-Gonearrestide Journal article
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2018,Volume: 22,Issue: 9,Page: 4460-4473
Authors:  Li, Bin;  Lyu, Peng;  Xi, Xinping;  Ge, Lilin;  Mahadevappa, Ravikiran;  Shaw, Chris;  Kwok, Hang Fai
Favorite  |  View/Download:9/0  |  Submit date:2018/10/30
Anticancer Mechanism  Binding Sites  Ms  Ms Proteome  Ngs Transcriptome  Signalling Pathways  Venom Library  
Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 830,Page: 17-25
Authors:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping;  Wang, Yitao;  Li, Ao;  Lin, Li-Gen;  Lu, Jin-Jian
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Nagilactone e  Non-small Cell Lung Cancer  Cyclin B1  Cell Cycle  Apoptosis  
Fast identification of anticancer constituents in Forsythiae Fructus based on metabolomics approaches Journal article
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2018,Volume: 154,Page: 312-320
Authors:  Bao, Jiaolin;  Ding, Ren-Bo;  Jia, Xuejing;  Liang, Yeer;  Liu, Fang;  Wang, Kai;  Zhang, Chao;  Li, Peng;  Wang, Yitao;  Wan, Jian-Bo;  He, Chengwei
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Forsythiae Fructus  Anticancer  Metabolomics  Multivariate Data Analysis  B16-f10 Melanoma  
Garcinone E induces apoptosis and inhibits migration and invasion in ovarian cancer cells Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Xu, Xiao-Huang;  Liu, Qian-Yu;  Li, Ting;  Liu, Jian-Lin;  Chen, Xin;  Huang, Li;  Qiang, Wen-An;  Chen, Xiuping;  Wang, Yitao;  Lin, Li-Gen;  Lu, Jin-Jian
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Modulating the phenotype of host macrophages to enhance osteogenesis in MSC-laden hydrogels: Design of a glucomannan coating material Journal article
BIOMATERIALS, 2017,Volume: 139,Page: 39-55
Authors:  Niu, Yiming;  Li, Qiu;  Xie, Ruiyu;  Liu, Shang;  Wang, Ruibing;  Xing, Panfei;  Shi, Yuchen;  Wang, Yitao;  Dong, Lei;  Wang, Chunming
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Bioactive Coating  Glucomannan Polysaccharides  Scaffold-tissue Integration  Macrophages  Osteogenesis  
Chikusetsusaponin IVa methyl ester induces G1 cell cycle arrest, triggers apoptosis and inhibits migration and invasion in ovarian cancer cells Journal article
PHYTOMEDICINE, 2017,Volume: 29,Page: E1-E1
Authors:  Chen, Xin;  Wu, Qiu-Shuang;  Meng, Fan-Cheng;  Tang, Zheng-Hai;  Chen, Xiuping;  Lin, Li-Gen;  Chen, Ping;  Qiang, Wen-An;  Wang, Yi-Tao;  Zhang, Qing-Wen;  Lu, Jin-Jian
Favorite  |  View/Download:16/0  |  Submit date:2018/10/30
Cytotoxic and apoptosis-inducing activity of C-21 steroids from the roots of Cynanchum atratum Journal article
STEROIDS, 2017,Volume: 122,Page: 1-8
Authors:  Zhang, Jian;  Ma, Lin;  Wu, Zheng-Feng;  Yu, Shu-Le;  Wang, Lei;  Ye, Wen-Cai;  Zhang, Qing-Wen;  Yin, Zhi-Qi
Favorite  |  View/Download:8/0  |  Submit date:2018/10/30
Cynanchum atratum  C-21 steroids  Cytotoxic activity  Apoptosis  Mitochondrial pathway  
Co-delivery of paclitaxel and tetrandrine via iRGD peptide conjugated lipid-polymer hybrid nanoparticles overcome multidrug resistance in cancer cells Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Zhang, Jinming;  Wang, Lu;  Chan, Hon Fai;  Xie, Wei;  Chen, Sheng;  He, Chengwei;  Wang, Yitao;  Chen, Meiwan
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Cytotoxic and apoptosis-inducing activity of C21 steroids from the roots of Cynanchum atratum Journal article
Steroids, 2017,Volume: 122,Page: 1-8
Authors:  Zhang J.;  Ma L.;  Wu Z.-F.;  Yu S.-L.;  Wang L.;  Ye W.-C.;  Zhang Q.-W.;  Yin Z.-Q.
Favorite  |  View/Download:0/0  |  Submit date:2018/12/28
Apoptosis  C21 steroids  Cynanchum atratum  Cytotoxic activity  Mitochondrial pathway  
Shikonin derivative DMAKO-05 inhibits akt signal activation and melanoma proliferation Journal article
Chemical Biology and Drug Design, 2016,Volume: 87,Issue: 6,Page: 895-904
Authors:  Yang Y.-Y.;  He H.-Q.;  Cui J.-H.;  Nie Y.-J.;  Wu Y.-X.;  Wang R.;  Wang G.;  Zheng J.-N.;  Ye R.D.;  Wu Q.;  Li S.-S.;  Qian F.
Favorite  |  View/Download:1/0  |  Submit date:2018/11/07
apoptosis  cell cycle arrest  cytotoxicity  DMAKO-05  melanoma cell B16F0  shikonin