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Tetrandrine inhibits differentiation of proinflammatory subsets of T helper cells but spares de novo differentiation of iTreg cells Journal article
INTERNATIONAL IMMUNOPHARMACOLOGY, 2019,Volume: 69,Page: 307-312
作者:  Zou, HM;  He, TZ;  Chen, X
收藏  |  浏览/下载:3/0  |  提交时间:2019/05/08
Tetrandrine  Itreg Cells  Th17 Cells  Th2 Cells  Th1 Cells  
TNFR2-expressing CD4(+) Foxp3(+) regulatory T cells in cancer immunology and immunotherapy Journal article
Progress in Molecular Biology and Translational Science, 2019
作者:  Jiang He;  Ruixin Li;  Yibo Chen;  Yuanjia Hu;  Xin Chen
收藏  |  浏览/下载:10/0  |  提交时间:2019/05/08
Regulatory t Cells  Immunotherapy  Cancer  Tumor Necrosis Factor Receptor Type 2  Tumor Necrosis Factor  
MK2 mediates macrophage activation and acute lung injury by regulating let-7e miRNA Journal article
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2018,Volume: 315,Issue: 3,Page: L371-L381
作者:  Wu, Yaxian;  He, Huiqiong;  Ding, Yunhe;  Liu, Sirui;  Zhang, Depeng;  Wang, Jun;  Jiang, Hongchao;  Zhang, Dan;  Sun, Lei;  Ye, Richard D.;  Qian, Feng
浏览  |  Adobe PDF(2092Kb)  |  收藏  |  浏览/下载:132/10  |  提交时间:2018/10/30
acute lung injury  let-7e  lipopolysaccharides  macrophage  MAPK-activated protein kinase 2  miRNA  MK2  
The p38 MAPK inhibitor SB203580 abrogates tumor necrosis factor-induced proliferative expansion of mouse CD4+Foxp3+ regulatory T cells Journal article
Frontiers in Immunology, 2018,Volume: 9,Issue: JUL
作者:  He T.;  Liu S.;  Chen S.;  Ye J.;  Wu X.;  Bian Z.;  Chen X.
收藏  |  浏览/下载:19/0  |  提交时间:2018/11/06
cd4+foxp3+ Regulatory t Cells  P38 Mapk  Proliferation  Tnf Receptor Type Ii  Tumor Necrosis Factor  
The p38 MaPK inhibitor sB203580 abrogates Tumor necrosis Factor-induced Proliferative expansion of Mouse cD4(+)Foxp3(+) regulatory T cells Journal article
FRONTIERS IN IMMUNOLOGY, 2018,Volume: 9
作者:  He, Tianzhen;  Liu, Shuoyang;  Chen, Shaokui;  Ye, Jingyi;  Wu, Xueqiang;  Bian, Zhaoxiang;  Chen, Xin
收藏  |  浏览/下载:12/0  |  提交时间:2018/10/30
tumor necrosis factor  TNF receptor type II  p38 MAPK  CD4(+)Foxp3(+) regulatory T cells  proliferation  
TNF Receptor Type II as an Emerging Drug Target for the Treatment of Cancer, Autoimmune Diseases, and Graft-Versus-Host Disease: Current Perspectives and In Silico Search for Small Molecule Binders Journal article
FRONTIERS IN IMMUNOLOGY, 2018,Volume: 9
作者:  Shaikh, Faraz;  He, Jiang;  Bhadra, Pratiti;  Chen, Xin;  Siu, Shirley W., I
收藏  |  浏览/下载:20/0  |  提交时间:2018/10/30
Tnf Receptor Type Ii  Tnf  Regulatory t Cells  Virtual Screening  Drug Discovery  Mm-pbsa  
Modulation of Regulatory T Cell Activity by TNF Receptor Type II-Targeting Pharmacological Agents Journal article
FRONTIERS IN IMMUNOLOGY, 2018,Volume: 9
作者:  Zou, Huimin;  Li, Ruixin;  Hu, Hao;  Hu, Yuanjia;  Chen, Xin
收藏  |  浏览/下载:11/0  |  提交时间:2018/10/30
Tnf Receptor Type Ii  Regulatory t Cells  Tnf Receptor Type Ii Agonists  Tnf Receptor Type Ii Antagonists  Immunotherapy  
Blockade of TNFR2 signaling enhances the immunotherapeutic effect of CpG ODN in a mouse model of colon cancer Journal article
SCIENCE SIGNALING, 2018,Volume: 11,Issue: 511
作者:  Nie, Yingjie;  He, Jiang;  Shirota, Hidekazu;  Trivett, Anna L.;  Yang, De;  Klinman, Dennis M.;  Oppenheim, Joost J.;  Chen, Xin
收藏  |  浏览/下载:16/0  |  提交时间:2018/10/30
Targeting TNFR2, an immune checkpoint stimulator and oncoprotein, is a promising treatment for cancer Journal article
SCIENCE SIGNALING, 2017,Volume: 10,Issue: 462
作者:  Chen, Xin;  Oppenheim, Joost J.
收藏  |  浏览/下载:12/0  |  提交时间:2018/10/30
TNFR2 expression by CD4 effector T cells is required to induce full-fledged experimental colitis Journal article
Scientific Reports, 2016,Volume: 6
作者:  Chen X.;  Nie Y.;  Xiao H.;  Bian Z.;  Scarzello A.J.;  Song N.-Y.;  Anna T.L.;  Yang D.;  Oppenheim J.J.
收藏  |  浏览/下载:7/0  |  提交时间:2018/11/06