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Tanshinone IIA attenuates insulin like growth factor 1-induced cell proliferation in PC12 cells through the PI3K/Akt and MEK/ERK pathways Journal article
International Journal of Molecular Sciences, 2018,Volume: 19,Issue: 9
Authors:  Wang H.;  Su X.;  Fang J.;  Xin X.;  Zhao X.;  Gaur U.;  Wen Q.;  Xu J.;  Little P.J.;  Zheng W.
Favorite  |  View/Download:6/0  |  Submit date:2018/12/21
Akt  Antiproliferation  ERK  IGF-1R  Tanshinone IIA  
Forkhead box protein O3 suppresses uveal melanoma development by increasing the expression of Bcl-2-like protein 11 and cyclin-dependent kinase inhibitor 1B Journal article
MOLECULAR MEDICINE REPORTS, 2018,Volume: 17,Issue: 2,Page: 3109-3114
Authors:  Yan, Fengxia;  Liao, Rifang;  Lin, Shaofen;  Deng, Xianguo;  Little, Peter J.;  Zheng, Wenhua
Favorite  |  View/Download:17/0  |  Submit date:2018/10/30
uveal melanoma  forkhead box protein O3  cell cycle phase  uveal melanoma cells  
gamma-Mangostin, a xanthone from mangosteen, attenuates oxidative injury in liver via NRF2 and SIRT1 induction Journal article
JOURNAL OF FUNCTIONAL FOODS, 2018,Volume: 40,Page: 544-553
Authors:  Wang, Anqi;  Li, Dan;  Wang, Shengpeng;  Zhou, Fayang;  Li, Peng;  Wang, Yitao;  Lin, Ligen
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Gamma-mangostin  Mangosteen  Liver Oxidative Injury  Nrf2  Sirt1  Pgc-1 Alpha  
Redox-sensitive micelles composed of disulfide-linked Pluronic-linoleic acid for enhanced anticancer efficiency of brusatol Journal article
INTERNATIONAL JOURNAL OF NANOMEDICINE, 2018,Volume: 13,Page: 939-956
Authors:  Zhane, Jinming;  Fang, Xiaobin;  Li, Zeyong;  Chan, Hon Fai;  Lin, Zhixiu;  Wang, Yitao;  Chen, Meiwan
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Poloxamer188  Tumor Micro-environment  Glutathione  Brucea Javanica  Cancer Treatment  
Amiodarone-Induced Retinal Neuronal Cell Apoptosis Attenuated by IGF-1 via Counter Regulation of the PI3k/Akt/FoxO3a Pathway Journal article
MOLECULAR NEUROBIOLOGY, 2017,Volume: 54,Issue: 9,Page: 6931-6943
Authors:  Liao, Rifang;  Yan, Fengxia;  Zeng, Zhuanping;  Farhan, Mohd;  Little, Peter;  Quirion, Remi;  Srivastava, Lalit K.;  Zheng, Wenhua
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Amiodarone  Foxo3a  Akt  Antiarrhythmic  Apoptosis  Neuroprotection  
The Atypical Antipsychotic Agent, Clozapine, Protects Against Corticosterone-Induced Death of PC12 Cells by Regulating the Akt/FoxO3a Signaling Pathway Journal article
MOLECULAR NEUROBIOLOGY, 2017,Volume: 54,Issue: 5,Page: 3395-3406
Authors:  Zeng, Zhiwen;  Wang, Xue;  Bhardwaj, Sanjeev K.;  Zhou, Xuanhe;  Little, Peter J.;  Quirion, Remi;  Srivastava, Lalit K.;  Zheng, Wenhua
Favorite  |  View/Download:15/0  |  Submit date:2018/10/30
Schizophrenia  Clozapine  Corticosterone  Pi3k/akt/foxo3a  Neuroprotection  
AKT2 regulates pulmonary inflammation and fibrosis via modulating macrophage activation Journal article
Journal of Immunology, 2017,Volume: 198,Issue: 11,Page: 4470-4480
Authors:  Nie Y.;  Sun L.;  Wu Y.;  Yang Y.;  Wang J.;  He H.;  Hu Y.;  Chang Y.;  Liang Q.;  Zhu J.;  Ye R.D.;  Christman J.W.;  Qian F.
Favorite  |  View/Download:0/0  |  Submit date:2018/11/07
AKT2 Regulates Pulmonary Inflammation and Fibrosis via Modulating Macrophage Activation Journal article
JOURNAL OF IMMUNOLOGY, 2017,Volume: 198,Issue: 11,Page: 4470-4480
Authors:  Nie, Yunjuan;  Sun, Lei;  Wu, Yaxian;  Yang, Yaoyao;  Wang, Jun;  He, Huiqiong;  Hu, Yudong;  Chang, Yanhua;  Liang, Qing;  Zhu, Jianwei;  Ye, Richard D.;  Christman, John W.;  Qian, Feng
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Elucidating the role of the FoxO3a transcription factor in the IGF-1-induced migration and invasion of uveal melanoma cancer cells Journal article
Biomedicine and Pharmacotherapy, 2016,Volume: 84,Page: 1538-1550
Authors:  Yan F.;  Liao R.;  Farhan M.;  Wang T.;  Chen J.;  Wang Z.;  Little P.J.;  Zheng W.
Favorite  |  View/Download:4/0  |  Submit date:2018/12/21
FoxO3a translocation  IGF-1  Metastases  Uveal melanoma  
The role of Akt/FoxO3a in the protective effect of venlafaxine against corticosterone-induced cell death in PC12 cells Journal article
Psychopharmacology, 2013,Volume: 228,Issue: 1,Page: 129-141
Authors:  Wang H.;  Zhou X.;  Huang J.;  Mu N.;  Guo Z.;  Wen Q.;  Wang R.;  Chen S.;  Feng Z.-P.;  Zheng W.
Favorite  |  View/Download:4/0  |  Submit date:2018/12/21
Corticosterone  Neuroprotection  PI3K/Akt/FoxO3a  Venlafaxine