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The metabolic footprint during adipocyte commitment highlights ceramide modulation as an adequate approach for obesity treatment Journal article
EBioMedicine, 2020,Volume: 51
Authors:  Hou,Weilong;  Chen,Qiang;  Wang,Haitao;  Qiu,Pengxiang;  Lyu,Xueying;  Chen,Weiping;  Chua,Melvin L.K.;  Chinn,Y. Eugene;  Deng,Chu Xia;  Wang,Ruihong
Favorite | View/Download:74/0 | TC[WOS]:0 TC[Scopus]:1 | Submit date:2020/09/16
Adipogenesis  Apoptosis  Ceramide  Epigenetic modification  Metabolic landscape  Metabolomics  Obesity  
Generation of Human Fatty Livers Using Custom-Engineered Induced Pluripotent Stem Cells with Modifiable SIRT1 Metabolism Journal article
Cell Metabolism, 2019,Volume: 30,Issue: 2,Page: 385-401.e9
Authors:  Collin de l'Hortet,Alexandra;  Takeishi,Kazuki;  Guzman-Lepe,J.;  Morita,Kazutoyo;  Achreja,Abhinav;  Popovic,Branimir;  Wang,Yang;  Handa,Kan;  Mittal,Anjali;  Meurs,Noah;  Zhu,Z.;  Weinberg,F.;  Salomon,Michael;  Fox,I. J.;  Deng,Chu Xia;  Nagrath,Deepak;  Soto-Gutierrez,Alejandro
Favorite | View/Download:73/0 | TC[WOS]:10 TC[Scopus]:13 | Submit date:2020/09/16
cellular engineering  hepatic differentiation  human fatty liver  human iPSCs  liver metabolism  NAFLD  NASH  SIRT1  
Repurposing vitamin D for treatment of human malignancies via targeting tumor microenvironment Journal article
ACTA PHARMACEUTICA SINICA B, 2019,Volume: 9,Issue: 2,Page: 203-219
Authors:  Xu Wu;  Wei Hu;  Lan Lu;  Yueshui Zhao;  Yejiang Zhou;  Zhangang Xiao;  Lin Zhang;  Hanyu Zhang;  Xiaobing Li;  Wanping Li;  Shengpeng Wang;  Chi Hin Cho;  Jing Shen;  Mingxing Li
Favorite | View/Download:12/0 | TC[WOS]:5 TC[Scopus]:14 | Submit date:2020/04/01
Vitamin d  1α,25-dihydroxyvitamin D3  Tumor Microenvironment  Cancer Stem Cell  Tumor-infiltrating Lymphocyte  Tumor-derived Endothelial Cell  Cancer-associated Fibroblast  
Essential oil of Citrus lumia Risso: Phytochemical profile, antioxidant properties and activity on the central nervous system Journal article
Food and Chemical Toxicology, 2018,Volume: 119,Page: 407-416
Authors:  Smeriglio A.;  Alloisio S.;  Raimondo F.M.;  Denaro M.;  Xiao J.;  Cornara L.;  Trombetta D.
Favorite | View/Download:11/0 | TC[WOS]:12 TC[Scopus]:16 | Submit date:2019/01/15
Anti-cholinesterase activity  Antioxidant properties  Citrus lumia Risso  Cytotoxicity  Essential oil  Neuroactive effects  
Periplaneta americana Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Rats by Keap1/Nrf-2 Activation, Intestinal Barrier Function, and Gut Microbiota Regulation Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:  Ma, Xuewei;  Hu, Yichen;  Li, Xin;  Zheng, Xiaoting;  Wang, Yitao;  Zhang, Jinming;  Fu, Chaomei;  Geng, Funeng
View | Adobe PDF | Favorite | View/Download:1193/20 | TC[WOS]:9 TC[Scopus]:19 | Submit date:2018/10/30
Ulcerative Colitis  Periplaneta Americana  16s Rrna  Gut Microbiota  Intestinal Immunity  
Silencing stem cell factor gene in fibroblasts to regulate paracrine factor productions and enhance c-Kit expression in melanocytes on melanogenesis Journal article
International Journal of Molecular Sciences, 2018,Volume: 19,Issue: 5
Authors:  Li P.-H.;  Liu L.-H.;  Chang C.-C.;  Gao R.;  Leung C.-H.;  Ma D.-L.;  David Wang H.-M.
Favorite | View/Download:11/0 | TC[WOS]:10 TC[Scopus]:15 | Submit date:2018/11/06
Fibroblasts  Melanin  Melanocytes  Paracrine Factors  Stem Cell Factor  
Generation of Smurf2 conditional knockout mice Journal article
International Journal of Biological Sciences, 2018,Volume: 14,Issue: 5,Page: 542-548
Authors:  Tang Y.;  Tang L.-Y.;  Xu X.;  Li C.;  Deng C.;  Zhang Y.E.
Favorite | View/Download:15/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2018/12/13
Knockout  Liver  Loxp  Mice  Smurf2  
Generation of Smurf2 conditional knockout mice Journal article
International Journal of Biological Sciences, 2018,Volume: 14,Issue: 5,Page: 542-548
Authors:  Tang,Yi;  Tang,Liu Ya;  Xu,Xuan;  Li,Cuiling;  Deng,Chuxia;  Zhang,Ying E.
Favorite | View/Download:5/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2020/09/16
Knockout  Liver  LoxP  Mice  Smurf2  
A native-like bispecific antibody suppresses the inflammatory cytokine response by simultaneously neutralizing tumor necrosis factor-alpha and interleukin-17A Journal article
ONCOTARGET, 2017,Volume: 8,Issue: 47,Page: 81860-81872
Authors:  Xu, Tianshu;  Ying, Tianlei;  Wang, Lili;  Zhang, Xiaohua Douglas;  Wang, Ying;  Kang, Lishan;  Huang, Tao;  Cheng, Liang;  Wang, Liping;  Zhao, Qi
Favorite | View/Download:30/0 | TC[WOS]:12 TC[Scopus]:10 | Submit date:2018/10/30
Bispecific Antibody  Fc Heterodimerization  Tnf-alpha  Il-17  Rheumatoid Arthritis  Immunology And Microbiology Section  Immune Response  Immunity  
Temporal establishment of neural cell identity in vivo and in vitro Journal article
JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 2017,Volume: 11,Issue: 9,Page: 2582-2589
Authors:  Yuen, Shun Ming;  Kwok, Hang Fai
Favorite | View/Download:20/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2018/10/30
Temporal Regulation  Neural Stem Cells  Embryonic Stem Cells  Induced Pluripotent Stem Cells  Cis-regulatory Elements  Cell Fates  Neural Specification