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Adeno-Associated Virus-Mediated RNAi against Mutant Alleles Attenuates Abnormal Calvarial Phenotypes in an Apert Syndrome Mouse Model Journal article
Molecular Therapy - Nucleic Acids, 2018,Volume: 13,Page: 291-302
Authors:  Luo F.;  Xie Y.;  Wang Z.;  Huang J.;  Tan Q.;  Sun X.;  Li F.;  Li C.;  Liu M.;  Zhang D.;  Xu M.;  Su N.;  Ni Z.;  Jiang W.;  Chang J.;  Chen H.;  Chen S.;  Xu X.;  Deng C.;  Wang Z.;  Du X.;  Chen L.
Favorite  |  View/Download:19/0  |  Submit date:2018/12/13
Adeno-associated Virus  Apert Syndrome  Craniosynostosis  Fgfr2  Molecular Therapy  Rnai  
A novel FGFR1-binding peptide attenuates the degeneration ofarticular cartilage in adult mice Journal article
Osteoarthritis and Cartilage, 2018,Volume: 26,Issue: 12,Page: 1733-1743
Authors:  Q. Tan;  B. Chen;  Q. Wang;  W.Xu;  Y.Wang;  Z. Lin;  F.Luo;  S. Huang;  Y.Zhu;  N. Su;  M. Jin;  C.Li;  L. Kuang;  H.Qi;  Z.Ni;  Z. Wang;  X. Luo;  W. Jiang;  H. Chen;  S. Chen;  F.Li;  B. Zhang;  J. Huang;  R. Zhang;  K. Jin;  X.Xu;  C. Deng;  X.Du;  Y. Xie;  L. Chen
Favorite  |  View/Download:19/0  |  Submit date:2018/12/17
Fgfr1  Peptide  Osteoarthritis  Mice  
Optimizing CRISPR/Cas9 technology for precise correction of the Fgfr3-Gly374Arg mutation in achondroplasia in mice Journal article
The Journal of Biological Chemistry, 2018
Authors:  Kai Miao;  Xin Zhang;  Sek Man Su;  Jianming Zeng;  Zebin Huang;  Un In Chan;  Xiaoling Xu;  Chu-Xia Deng
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Fgfr3  Crispr/cas9  Protein  Targeted Correction  Off-target  Achondroplasia  Dwarfism  Genome Editing  Gene Therapy  
Vascular endothelial growth factor gene transfer therapy for coronary artery disease: A systematic review and meta-analysis Journal article
CARDIOVASCULAR THERAPEUTICS, 2018,Volume: 36,Issue: 5
Authors:  Yuan, Rong;  Xin, Qiqi;  Shi, Weili;  Liu, Wei;  Lee, Simon-M.;  Hoi, Puiman;  Li, Lin;  Zhao, Jun;  Cong, Weihong;  Chen, Keji
View  |  Adobe PDF(849Kb)  |  Favorite  |  View/Download:339/15  |  Submit date:2018/10/30
Angina Pectoris  Angiogenesis Inducing Agents  Coronary Artery Disease  Genetic Therapy  Myocardial Ischemia  Vascular Endothelial Growth Factor  
Toosendanin, a natural product, inhibited TGF-1-induced epithelial-mesenchymal transition through ERK/Snail pathway Journal article
PHYTOTHERAPY RESEARCH, 2018,Volume: 32,Issue: 10,Page: 2009-2020
Authors:  Luo, Weiwei;  Liu, Xin;  Sun, Wen;  Lu, Jin-Jian;  Wang, Yitao;  Chen, Xiuping
View  |  Adobe PDF(2621Kb)  |  Favorite  |  View/Download:583/30  |  Submit date:2018/10/30
Emt  Erk1/2  Snail  Lung Cancer  Toosendanin  
A novel FGFR1-binding peptide exhibits anti-tumor effect on lung cancer by inhibiting proliferation and angiogenesis Journal article
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2018,Volume: 14,Issue: 10,Page: 1389-1398
Authors:  Tan, Qiaoyan;  Wang, Zuqiang;  Wang, Quan;  Wang, Yuanqiang;  Huang, Zhifeng;  Su, Nan;  Jin, Min;  Kuang, Liang;  Qi, Huabing;  Ni, Zhenhong;  Li, Can;  Zhu, Ying;  Jiang, Wanling;  Chen, Hangang;  Deng, Chuxia;  Du, Xiaolan;  Xie, Yangli;  Chen, Lin
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Phage Display  Fgfr1  Peptide  Cancer Therapy  Lung Cancer  
Fibroblast Grouth Factor Receptor (FGFR2) Mutation Related Symdromic Craniosynostosis Journal article
International Journal of Biological Sciences, 2017,Volume: 13,Issue: 12,Page: 1479-1488
Authors:  Saïd C. Azoury;  Sashank Reddy;  Vivek Shukla;  Chu-Xia Deng
Favorite  |  View/Download:8/0  |  Submit date:2018/12/17
Fibroblast Growth Factor Receptor  Mutations, Syndromic  Craniosynostosis  
Inducible Activation of FGFR2 in Adult Mice Promotes Bone Formation After Bone Marrow Ablation Journal article
JOURNAL OF BONE AND MINERAL RESEARCH, 2017,Volume: 32,Issue: 11,Page: 2194-2206
Authors:  Xu, Wei;  Luo, Fengtao;  Wang, Quan;  Tan, Qiaoyan;  Huang, Junlan;  Zhou, Siru;  Wang, Zuqiang;  Sun, Xianding;  Kuang, Liang;  Jin, Min;  Su, Nan;  Jiang, Wanling;  Chen, Liang;  Qi, Huabing;  Zhu, Ying;  Chen, Bo;  Chen, Hangang;  Chen, Shuai;  Gao, Yu;  Xu, Xiaoling;  Deng, Chuxia;  Chen, Lin;  Xie, Yangli;  Du, Xiaolan
Favorite  |  View/Download:19/0  |  Submit date:2018/10/30
Bone Marrow Ablation  Fgfr2  Bone Formation  Wnt/beta-catenin  
Fibroblast Growth Factor Receptor 2 (FGFR2) Mutation Related Syndromic Craniosynostosis Journal article
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2017,Volume: 13,Issue: 12,Page: 1479-1488
Authors:  Azoury, Said C.;  Reddy, Sashank;  Shukla, Vivek;  Deng, Chu-Xia
Favorite  |  View/Download:11/0  |  Submit date:2018/10/30
Fibroblast Growth Factor Receptor  Mutations  Syndromic  Craniosynostosis  
Fibroblast Growth Factor Receptor 2 Signaling in Breast Cancer Journal article
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2017,Volume: 13,Issue: 9,Page: 1163-1171
Authors:  Lei, Haipeng;  Deng, Chu-Xia
Favorite  |  View/Download:11/0  |  Submit date:2018/10/30
Breast Cancer  Fgfr2  Mutation  Polymorphism  Inhibitor