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Non-classical estrogen signaling in ovarian cancer improves chemo-sensitivity and patients outcome Journal article
THERANOSTICS, 2019,Volume: 9,Issue: 13,Page: 3952-3965
Authors:  Dapeng Hao;  Jingjing Li;  Jianlin Wang;  Yuan Meng;  Zhiqiang Zhao;  Chao Zhang;  Kai Miao;  Chuxia Deng;  Benjamin K. Tsang;  Li Wang;  Li-jun Di
Favorite  |  View/Download:9/0  |  Submit date:2020/05/21
Ovarian Cancer  Estrogen Signaling  Deficiency Of Homologous-recombination  Chemotherapy  Hormone Replacement  
Single-Cell Transcriptome Analysis Reveals Estrogen Signaling Coordinately Augments One-Carbon, Polyamine, and Purine Synthesis in Breast Cancer Journal article
Cell Reports, 2018,Volume: 25,Issue: 8,Page: 2285-2298.e4
Authors:  Zhu D.;  Zhao Z.;  Cui G.;  Chang S.;  Hu L.;  See Y.X.;  Lim M.G.L.;  Guo D.;  Chen X.;  Robson P.;  Luo Y.;  Cheung E.
Favorite  |  View/Download:13/0  |  Submit date:2018/12/17
Breast Cancer  Estrogen Receptor α  Metabolic Switch  Single-cell Rna Sequencing  
BRCA1 represses DNA replication initiation through antagonizing estrogen signaling and maintains genome stability in parallel with WEE1-MCM2 signaling during pregnancy Journal article
Human molecular genetics, 2018
Authors:  Xiaoling Xu;  Eric Chen;  Lihua Mo;  Lei Zhang;  Fangyuan Shao;  Kai Miao;  Jianlin Liu;  Sek Man Su;  Monica Valecha;  Un In Chan;  Hongping Zheng;  Mark Chen;  Weiping Chen;  Qiang Chen;  Haiqing Fu;  Mirit I. Aladjem;  Yanzhen He;  Chu-Xia Deng
Favorite  |  View/Download:35/0  |  Submit date:2018/12/17
DNA replication licensing protein MCM10 promotes tumor progression and is a novel prognostic biomarker and potential therapeutic target in breast cancer Journal article
Cancers, 2018,Volume: 10,Issue: 9
Authors:  Mahadevappa R.;  Neves H.;  Yuen S.M.;  Jameel M.;  Bai Y.;  Yuen H.-F.;  Zhang S.-D.;  Zhu Y.;  Lin Y.;  Kwok H.F.
Favorite  |  View/Download:8/0  |  Submit date:2018/12/19
Breast Cancer  Knockdown  Mcm10  Overexpression  Proliferation  Survival  
A novel Ca2+ current blocker promotes angiogenesis and cardiac healing after experimental myocardial infarction in mice Journal article
PHARMACOLOGICAL RESEARCH, 2018,Volume: 134,Page: 109-117
Authors:  Cui, Guozhen;  Xin, Qiqi;  Tseng, Hisa Hui Ling;  Hoi, Maggie PuiMan;  Wang, Yan;  Yang, Binrui;  Choi, InLeng;  Wang, Yuqiang;  Yuan, Rong;  Chen, Keji;  Cong, Weihong;  Lee, Simon MingYuen
View  |  Adobe PDF(3018Kb)  |  Favorite  |  View/Download:285/12  |  Submit date:2018/10/30
Cardioprotection  Angiogenesis  ADTM  Zebrafish  VEGF  
Physalin B induces cell cycle arrest and triggers apoptosis in breast cancer cells through modulating p53-dependent apoptotic pathway Journal article
BIOMEDICINE & PHARMACOTHERAPY, 2018,Volume: 101,Page: 334-341
Authors:  Wang, Anqi;  Wang, Shengpeng;  Zhou, Fayang;  Li, Peng;  Wang, Yitao;  Gan, Lishe;  Lin, Ligen
View  |  Adobe PDF(1614Kb)  |  Favorite  |  View/Download:302/19  |  Submit date:2018/10/30
Physalin b  Breast Cancer  Cell Cycle  Apoptosis  P53  Akt  
Inhibition of Estrogen Signaling Reduces the Incidence of BRCA1-associated Mammary Tumor Formation Journal article
International journal of biological sciences, 2018,Volume: 14,Issue: 12,Page: 1755-1768
Authors:  Baek H.J.;  Kim S.E.;  Choi E.K.;  Kim J.K.;  Shin D.H.;  Park E.J.;  Kim T.H.;  Kim J.-Y.;  Kim K.G.;  Deng C.-X.;  Kim S.S.
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Brca1  Cancer Prevention  Estrogen  Fulvestrant  
Potential therapeutic targets of triple-negative breast cancer based on its intrinsic subtype Journal article
ONCOTARGET, 2017,Volume: 8,Issue: 42,Page: 73329-73344
Authors:  Shao, Fangyuan;  Sun, Heng;  Deng, Chu-Xia
Favorite  |  View/Download:13/0  |  Submit date:2018/10/30
Cancer Therapy  Tnbc Subtype  Cscs  Drug Resistance  Cancer Targets  
Formononetin promotes angiogenesis through the estrogen receptor alpha-enhanced ROCK pathway Journal article
Scientific Reports, 2015,Volume: 5
Authors:  Li S.;  Dang Y.;  Zhou X.;  Huang B.;  Huang X.;  Zhang Z.;  Kwan Y.W.;  Chan S.W.;  Leung G.P.H.;  Lee S.M.Y.;  Hoi M.P.M.
Favorite  |  View/Download:14/0  |  Submit date:2018/11/06
BRCA1 And Estrogen/Estrogen Receptor In Breast Cancer: Where They Interact? Journal article
International Journal of Biological Sciences, 2014,Volume: 10,Issue: 5,Page: 566-575
Authors:  Li Wang;  Li-Jun Di
Favorite  |  View/Download:2/0  |  Submit date:2019/01/04
Estrogen  Oxidative Stress  Brca1  Mammary Gland Development  Ros  Breast Cancer  Cell Metabolism  Estrogen Receptor