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An Integrated Transfer Learning and Multitask Learning Approach for Pharmacokinetic Parameter Prediction Journal article
Molecular Pharmaceutics, 2019,Volume: 16,Issue: 2,Page: 533-541
Authors:  Ye Z.;  Yang Y.;  Li X.;  Cao D.;  Ouyang D.
Favorite  |  View/Download:7/0  |  Submit date:2019/02/14
ADME  deep learning  multitask learning  pharmacokinetic parameters  transfer learning  
Is metformin still the most efficacious first-line oral hypoglycaemic drug in treating type 2 diabetes? A network meta-analysis of randomized controlled trials Journal article
OBESITY REVIEWS, 2019,Volume: 20,Issue: 1,Page: 1-12
Authors:  Jia, Y.;  Lao, Y.;  Zhu, H.;  Li, N.;  Leung, S. -W.
Favorite  |  View/Download:18/0  |  Submit date:2019/01/17
hypoglycaemic control  network meta-analysis  randomized controlled trials  type 2 diabetes  
MK2 mediates macrophage activation and acute lung injury by regulating let-7e miRNA Journal article
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2018,Volume: 315,Issue: 3,Page: L371-L381
Authors:  Wu, Yaxian;  He, Huiqiong;  Ding, Yunhe;  Liu, Sirui;  Zhang, Depeng;  Wang, Jun;  Jiang, Hongchao;  Zhang, Dan;  Sun, Lei;  Ye, Richard D.;  Qian, Feng
View  |  Adobe PDF(2092Kb)  |  Favorite  |  View/Download:100/7  |  Submit date:2018/10/30
acute lung injury  let-7e  lipopolysaccharides  macrophage  MAPK-activated protein kinase 2  miRNA  MK2  
Supramolecular strategy for reducing the cardiotoxicity of bedaquiline without compromising its antimycobacterial efficacy Conference paper
FOOD AND CHEMICAL TOXICOLOGY, Kunming, PEOPLES R CHINA, AUG 25-30, 2018
Authors:  Kuok, Kit Ieng;  Ng, Phoebe Choi In;  Ji, Xia;  Wang, Chunming;  Yew, Wing Wai;  Chan, Denise P. C.;  Zheng, Jun;  Lee, Simon M. Y.;  Wang, Ruibing
View  |  Adobe PDF(423Kb)  |  Favorite  |  View/Download:158/22  |  Submit date:2018/10/30
Cucurbit[7]Uril  Bedaquiline  Supramolecular Formulation  Cardiotoxicity  Antimycobacterial  
Anti-cancer effects of Rhizoma Curcumae against doxorubicin-resistant breast cancer cells Journal article
CHINESE MEDICINE, 2018,Volume: 13
Authors:  Zhong, Zhangfeng;  Yu, Haibing;  Wang, Shengpeng;  Wang, Yitao;  Cui, Liao
View  |  Adobe PDF(2911Kb)  |  Favorite  |  View/Download:127/11  |  Submit date:2018/10/30
Rhizoma Curcumae  Multidrug Resistance  Breast Cancer  Abc Transporters  Furanodiene  
Periplaneta americana Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Rats by Keap1/Nrf-2 Activation, Intestinal Barrier Function, and Gut Microbiota Regulation Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:  Ma, Xuewei;  Hu, Yichen;  Li, Xin;  Zheng, Xiaoting;  Wang, Yitao;  Zhang, Jinming;  Fu, Chaomei;  Geng, Funeng
View  |  Adobe PDF(4337Kb)  |  Favorite  |  View/Download:233/10  |  Submit date:2018/10/30
Ulcerative Colitis  Periplaneta Americana  16s Rrna  Gut Microbiota  Intestinal Immunity  
Water soluble fraction from ethanolic extract of Clausena lansium seeds alleviates obesity and insulin resistance, and changes the composition of gut microbiota in high-fat diet-fed mice Journal article
JOURNAL OF FUNCTIONAL FOODS, 2018,Volume: 47,Page: 192-199
Authors:  Shen, Shengnan;  Liao, Qiwen;  Huang, Li;  Li, Dan;  Zhang, Qingwen;  Wang, Yitao;  Lee, Simon Ming-Yuen;  Lin, Ligen
View  |  Adobe PDF(1563Kb)  |  Favorite  |  View/Download:166/23  |  Submit date:2018/10/30
Clausena Lansium  Fat Mass Gain  Insulin Sensitivity  Gut Microbiota  Wampee  
Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 830,Page: 17-25
Authors:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping;  Wang, Yitao;  Li, Ao;  Lin, Li-Gen;  Lu, Jin-Jian
View  |  Adobe PDF(3226Kb)  |  Favorite  |  View/Download:143/20  |  Submit date:2018/10/30
Nagilactone e  Non-small Cell Lung Cancer  Cyclin B1  Cell Cycle  Apoptosis  
Targeting cancer metabolism to develop human lactate dehydrogenase (hLDH)5 inhibitors Journal article
DRUG DISCOVERY TODAY, 2018,Volume: 23,Issue: 7,Page: 1407-1415
Authors:  Zhang, Shao-Lin;  He, Yun;  Tam, Kin Yip
Favorite  |  View/Download:8/0  |  Submit date:2018/10/30
ADMETlab: a platform for systematic ADMET evaluation based on a comprehensively collected ADMET database Journal article
JOURNAL OF CHEMINFORMATICS, 2018,Volume: 10
Authors:  Dong, Jie;  Wang, Ning-Ning;  Yao, Zhi-Jiang;  Zhang, Lin;  Cheng, Yan;  Ouyang, Defang;  Lu, Ai-Ping;  Cao, Dong-Sheng
Favorite  |  View/Download:12/0  |  Submit date:2018/10/30
ADMETlab  ADMET  Drug-likeness  ADMET database  Drug discovery  Cheminformatics