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Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 10,Page: 1279-1291
Authors:  Lei Fan;  Xiao-xia Qiu;  Zhi-yuan Zhu;  Jian-lu Lv;  Jian Lu;  Fei Mao;  Jin Zhu;  Jia-ying Wang;  Xiao-wei Guan;  Jing Chen;  Jin Ren;  Ji-ming Ye;  Yong-hua Zhao;  Jian Li;  Xu Shen
Favorite | View/Download:16/0 | TC[WOS]:2 TC[Scopus]:0 | Submit date:2020/04/14
App/ps1 Transgenic Mice  Alzheimer’s Disease  Autophagy  Inflammation  Nitazoxanide  
Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 9,Page: 1193-1204
Authors:  Ting-ting Zhou;  Tong Zhao;  Fei Ma;  Yi-nan Zhang;  Jing Jiang;  Yuan Ruan;  Qiu-ying Yan;  Gai-hong Wang;  Jin Ren;  Xiao-wei Guan;  Jun Guo;  Yong-hua Zhao;  Ji-ming Ye;  Li-hong Hu;  Jing Chen;  Xu Shen
Favorite | View/Download:10/0 | TC[WOS]:1 TC[Scopus]:0 | Submit date:2020/04/14
Type 2 Diabetes Mellitus  Hepatic Gluconeogenesis  Ampk Signaling Pathway  (e)-3-(2-(Quinoline-4-yl)Vinyl)-1h-indol-6-ol (Qvo)  4-[2-(1h-indol-3-yl)Vinyl]Quinoline (Ivq)  Prodrug  
Alpinia zerumbet(Pers.): Food and Medicinal Plant with Potential In Vitro and In Vivo Anti-Cancer Activities Journal article
MOLECULES, 2019,Volume: 24,Issue: 13
Authors:  Maram Hussein Zahra;  Tarek A.R. Salem;  Bishoy El-Aarag;  Nermeen Yosri;  Samah EL-Ghlban;  Kholoud Zaki;  Amel H. Marei;  Aida Abd El-Wahed;  Aamer Saeed;  Alfi Khatib;  Mohamed F. AlAjmi;  Abdulrahman M. Shathili;  Jianbo Xiao;  Shaden A. M. Khalifa;  Hesham R. El-Seedi
Favorite | View/Download:16/0 | TC[WOS]:2 TC[Scopus]:0 | Submit date:2020/04/24
5,6-dehydrokawain  Alpinia Zerumbet  Ehrlich Ascites Carcinoma  Anti-oxidant  Anti-tumor  
Synthesis and biological evaluation of aza-crown ether–squaramide conjugates as anion/cation symporters Journal article
FUTURE MEDICINAL CHEMISTRY, 2019,Volume: 11,Issue: 10,Page: 1091-1106
Authors:  Xi-Hui Yu;  Xiong-Jie Cai;  Xiao-Qiao Hong;  Kin Yip Tam;  Kun Zhang;  Wen-Hua Chen
Favorite | View/Download:20/0 | TC[WOS]:2 TC[Scopus]:0 | Submit date:2020/05/21
A Survey of Force-Assisted Robotic Cell Microinjection Technologies Journal article
IEEE TRANSACTIONS ON AUTOMATION SCIENCE AND ENGINEERING, 2019,Volume: 16,Issue: 2,Page: 931 - 945
Authors:  Yuzhang Wei;  Qingsong Xu
Favorite | View/Download:47/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2019/04/18
Automated Robotic Injection  Biological Micromanipulation  Force Sensor  Microinjection  Small Force  
Arbutus species (Ericaceae) as source of valuable bioactive products Conference paper
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION, Kunming, PEOPLES R CHINA, 2018-8
Authors:  Maria Concetta Tenuta;  Rosa Tundis;  Jianbo Xiao;  Monica Rosa Loizzo;  Annabelle Dugay;  Brigitte Deguin
Favorite | View/Download:11/0 | TC[WOS]:3 TC[Scopus]:0 | Submit date:2020/04/27
Arbutus  Mediterranean  Chemical Constituents  Biological Properties  Functional Products  
An Integrated Transfer Learning and Multitask Learning Approach for Pharmacokinetic Parameter Prediction Journal article
Molecular Pharmaceutics, 2019,Volume: 16,Issue: 2,Page: 533-541
Authors:  Ye Z.;  Yang Y.;  Li X.;  Cao D.;  Ouyang D.
Favorite | View/Download:22/0 | TC[WOS]:5 TC[Scopus]:0 | Submit date:2019/02/14
Adme  Deep Learning  Multitask Learning  Pharmacokinetic Parameters  Transfer Learning  
Structure-Based Discovery of a Selective KDM5A Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines Journal article
CANCERS, 2019,Volume: 11,Issue: 1
Authors:  Yang, GJ;  Ko, CN;  Zhong, HJ;  Leung, CH;  Ma, DL
Favorite | View/Download:12/0 | TC[WOS]:7 TC[Scopus]:0 | Submit date:2020/03/24
Cell Cycle Arrest  Kdm5a  Jumonji Domain  Histone Demethylation  Protein-protein Interaction  Virtual Screening  Breast Cancer  Cell Senescence  
Small molecules for fat combustion: targeting thermosensory and satiety signals in the central nervous system Journal article
DRUG DISCOVERY TODAY, 2019,Volume: 24,Issue: 1,Page: 300-306
Authors:  JingxinLiu;  LigenLin
Favorite | View/Download:10/0 | TC[WOS]:1 TC[Scopus]:0 | Submit date:2020/03/20
LFB: A Novel Antimicrobial Brevinin-Like Peptide from the Skin Secretion of the Fujian Large Headed Frog, Limnonectes fujianensi Journal article
BIOMOLECULES, 2019,Volume: 9,Issue: 6
Authors:  Bin Li;  Peng Lyu;  Shuping Xie;  Haixin Qin;  Wenyuan Pu;  Houxi Xu;  Tianbao Chen;  Chris Shaw;  Lilin Ge;  Hang Fai Kwok
Favorite | View/Download:9/0 | TC[WOS]:1 TC[Scopus]:0 | Submit date:2020/05/20
Amphibian  Brevinin-like Peptide  Antimicrobial Peptides  Drug Discovery