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NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Miao,Kai;  Lei,Josh Haipeng;  Valecha,Monica Vishnu;  Zhang,Aiping;  Xu,Jun;  Wang,Lijian;  Lyu,Xueying;  Chen,Si;  Miao,Zhengqiang;  Zhang,Xin;  Su,Sek Man;  Shao,Fangyuan;  Rajendran,Barani Kumar;  Bao,Jiaolin;  Zeng,Jianming;  Sun,Heng;  Chen,Ping;  Tan,Kaeling;  Chen,Qiang;  Wong,Koon Ho;  Xu,Xiaoling;  Deng,Chu Xia
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Class I histone deacetylase inhibition is synthetic lethal with BRCA1 deficiency in breast cancer cells Journal article
Acta Pharmaceutica Sinica B, 2020,Volume: 10,Issue: 4,Page: 615-627
Authors:  Zhang,Baoyuan;  Lyu,Junfang;  Yang,Eun Ju;  Liu,Yifan;  Wu,Changjie;  Pardeshi,Lakhansing;  Tan,Kaeling;  Chen,Qiang;  Xu,Xiaoling;  Deng,Chu Xia;  Shim,Joong Sup
Favorite | View/Download:75/0 | TC[WOS]:0 TC[Scopus]:3 | Submit date:2020/09/16
BRCA1  Breast cancer  DNA damage  HDAC  Histone deacetylase  Reactive oxygen species  Synthetic lethality  
Nuclear localization of Desmoplakin and its involvement in telomere maintenance Journal article
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2019,Volume: 15,Issue: 11,Page: 2350-2362
Authors:  Peipei Li;  Yuan Meng;  Yuan Wang;  Jingjing Li;  Manting Lam;  Li Wang;  Li-jun Di
Favorite | View/Download:15/0 | TC[WOS]:1 TC[Scopus]:1 | Submit date:2020/05/21
Crispr Bioid Telomere Dsp  
PP2AC alpha deficiency impairs early cortical development through inducing DNA damage in neuroprojenitor cells Journal article
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2019,Volume: 109,Page: 40-58
Authors:  Bo Liu;  Lin Lin;  Saima Riazuddin;  Ahmed Zubair;  Li Wang;  Li-Jun Di;  Rui Li;  Ting-Ting Dong;  Chu-Xia Deng;  Wei-Min Tong
Favorite | View/Download:15/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2020/05/26
Protein Phosphorylation  Brain Development  Dna Damage  Stem Cell  Signaling Cascade  
Identification and characterization of antioxidant peptides from hydrolysate of blue-spotted stingray and their stability against thermal, pH and simulated gastrointestinal digestion treatments Conference paper
FOOD CHEMISTRY, Kunming, PEOPLES R CHINA, AUG 25-30, 2018
Authors:  Wong, Fai-Chu;  Xiao, Jianbo;  Ong, Michelle G-Ling;  Pang, Mei-Jing;  Wong, Shao-Jun;  Teh, Lai-Kuan;  Chai, Tsun-Thai
Favorite | View/Download:35/0 | TC[WOS]:16 TC[Scopus]:28 | Submit date:2018/10/30
Antioxidant Peptide  Dna Oxidation  Lipid Peroxidation  Ph Stability  Protein Oxidation  Purification  Simulated Gastrointestinal Digestion  Thermal Treatment  
BRCA1 represses DNA replication initiation through antagonizing estrogen signaling and maintains genome stability in parallel with WEE1-MCM2 signaling during pregnancy Journal article
Human molecular genetics, 2018
Authors:  Xiaoling Xu;  Eric Chen;  Lihua Mo;  Lei Zhang;  Fangyuan Shao;  Kai Miao;  Jianlin Liu;  Sek Man Su;  Monica Valecha;  Un In Chan;  Hongping Zheng;  Mark Chen;  Weiping Chen;  Qiang Chen;  Haiqing Fu;  Mirit I. Aladjem;  Yanzhen He;  Chu-Xia Deng
Favorite | View/Download:45/0 | TC[WOS]:0 TC[Scopus]:1 | Submit date:2018/12/17
Cyclin B1 stability is increased by interaction with BRCA1, and its overexpression suppresses the progression of BRCA1-associated mammary tumors Journal article
Experimental and Molecular Medicine, 2018,Volume: 50,Page: 136
Authors:  Choi, Eun Kyung;  Lim, Jeong-A;  Kim, Jong Kwang;  Jang, Moon Sun;  Kim, Sun Eui;  Baek, Hye Jung;  Park, Eun Jung;  Kim, Tae Hyun;  Deng, Chu-Xia;  Wang, Rui-Hong;  Kim, Sang Soo
Favorite | View/Download:40/0 | TC[WOS]:2 TC[Scopus]:4 | Submit date:2018/10/30
Cyclin B1 stability is increased by interaction with BRCA1, and its overexpression suppresses the progression of BRCA1-associated mammary tumors Journal article
Experimental and Molecular Medicine, 2018,Volume: 50,Issue: 10
Authors:  Choi,Eun Kyung;  Lim,Jeong A.;  Kim,Jong Kwang;  Jang,Moon Sun;  Kim,Sun Eui;  Baek,Hye Jung;  Park,Eun Jung;  Kim,Tae Hyun;  Deng,Chu Xia;  Wang,Rui Hong;  Kim,Sang Soo
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Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2018,Volume: 26,Issue: 18,Page: 5053-5061
Authors:  Chen, Shao-Ru;  Li, Feng;  Ding, Mo-Yu;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Zhou, Guo-Chun;  Wang, Ying
View | Adobe PDF | Favorite | View/Download:1322/88 | TC[WOS]:3 TC[Scopus]:5 | Submit date:2018/10/30
Andrographolide  Stat3 Inhibitor  Acute Liver Damage  Inflammation  
Inhibition of estrogen signaling reduces the incidence of BRCA1-associated mammary tumor formation Journal article
International Journal of Biological Sciences, 2018,Volume: 14,Issue: 12,Page: 1755-1768
Authors:  Baek,Hye Jung;  Kim,Sun Eui;  Choi,Eun Kyung;  Kim,Jong Kwang;  Shin,Dong Hoon;  Park,Eun Jung;  Kim,Tae Hyun;  Kim,Joo Young;  Kim,Kwang Gi;  Deng,Chu Xia;  Kim,Sang Soo
Favorite | View/Download:4/0 | TC[WOS]:2 TC[Scopus]:2 | Submit date:2020/09/16
BRCA1  Cancer prevention  Estrogen  Fulvestrant