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Hydroxyurea Facilitates Manifestation of Disease Relevant Phenotypes in Patients-Derived IPSCs-Based Modeling of Late-Onset Parkinson’s Disease Journal article
AGING AND DISEASE, 2019,Volume: 10,Issue: 5,Page: 1037-1048
Authors:  Yuan Tan;  Minjing Ke;  Zhijian Huang;  Cheong-Meng Chong;  Xiaotong Cen;  Jia-Hong Lu;  Xiaoli Yao;  Dajiang Qin;  Huanxing Su
Favorite  |  View/Download:15/0  |  Submit date:2020/04/08
Disease Phenotypes  Er Stress  Induced Pluripotentstem Cells  Parkinson’s Disease  Hydroxyurea  
ATP13A2 facilitates HDAC6 recruitment to lysosome to promote autophagosome–lysosome fusion Journal article
JOURNAL OF CELL BIOLOGY, 2019,Volume: 218,Issue: 1,Page: 267-284
Authors:  Ruoxi Wang;  Jieqiong Tan;  Tingting Chen;  Hailong Han;  Runyi Tian;  Ya Tan;  Yiming Wu;  Jingyi Cu;  Fang Chen;  Jie Li;  Lu Lv;  Xinjie Guan;  Shuai Shang;  Jiahong Lu;  Zhuohua Zhang
Favorite  |  View/Download:9/0  |  Submit date:2020/04/14
Optimizing CRISPR/Cas9 technology for precise correction of the Fgfr3-Gly374Arg mutation in achondroplasia in mice Journal article
The Journal of Biological Chemistry, 2018
Authors:  Kai Miao;  Xin Zhang;  Sek Man Su;  Jianming Zeng;  Zebin Huang;  Un In Chan;  Xiaoling Xu;  Chu-Xia Deng
Favorite  |  View/Download:25/0  |  Submit date:2018/12/17
Fgfr3  Crispr/cas9  Protein  Targeted Correction  Off-target  Achondroplasia  Dwarfism  Genome Editing  Gene Therapy  
Presenilin 1 deficiency suppresses autophagy in human neural stem cells through reducing γ-secretase-independent ERK/CREB signaling Journal article
CELL DEATH & DISEASE, 2018,Volume: 9,Page: 1-13
Authors:  Cheong-Meng Chong;  Minjing Ke;  Yuan Tan;  Zhijian Huang;  Ke Zhang;  Nana Ai;  Wei Ge;  Dajiang Qin;  Jia-Hong Lu;  Huanxing Su
Favorite  |  View/Download:35/0  |  Submit date:2018/10/30
Dysbindin-1 Involvement in the Etiology of Schizophrenia Journal article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017,Volume: 18,Issue: 10
Authors:  Wang, Haitao;  Xu, Jiangping;  Lazarovici, Philip;  Zheng, Wenhua
Favorite  |  View/Download:13/0  |  Submit date:2018/10/30
schizophrenia  dysbindin-1  susceptibility gene  neurotransmitter release  neurite outgrowth  
Arctigenin suppresses renal interstitial fibrosis in a rat model of obstructive nephropathy Journal article
PHYTOMEDICINE, 2017,Volume: 30,Page: 28-41
Authors:  Li, Ao;  Zhang, Xiaoxun;  Shu, Mao;  Wu, Mingjun;  Wang, Jun;  Zhang, Jingyao;  Wang, Rui;  Li, Peng;  Wang, Yitao
View  |  Adobe PDF(6898Kb)  |  Favorite  |  View/Download:347/5  |  Submit date:2018/10/30
Arctigenin  Renal Fibrosis  Inflammation  Transforming Growth Factor-beta 1  Oxidative Stress  Epithelial-mesenchymal Transition  
Mori Cortex regulates P-glycoprotein in Caco-2 cells and colons from rats with experimental colitis via direct and gut microbiota-mediated mechanisms Journal article
RSC ADVANCES, 2017,Volume: 7,Issue: 5,Page: 2594-2605
Authors:  Jing, Wanghui;  Gao, Xuejiao;  Han, Beilei;  Wei, Bin;  Hu, Nan;  Li, Sai;  Yan, Ru;  Wang, Yitao
View  |  Adobe PDF(1193Kb)  |  Favorite  |  View/Download:376/10  |  Submit date:2018/10/30
Vascular ADAM17 as a Novel Therapeutic Target in Mediating Cardiovascular Hypertrophy and Perivascular Fibrosis Induced by Angiotensin II Journal article
Hypertension, 2016,Volume: 68,Issue: 4,Page: 949-955
Authors:  Takayanagi T.;  Forrester S.J.;  Kawai T.;  Obama T.;  Tsuji T.;  Elliott K.J.;  Nuti E.;  Rossello A.;  Kwok H.F.;  Scalia R.;  Rizzo V.;  Eguchi S.
Favorite  |  View/Download:10/0  |  Submit date:2018/12/19
End-organ Damage  Fibrosis  Hypertension  Renin Angiotensin System  Signal Transduction  
Pleiotropic effects of peroxisome proliferator-activated receptor γ and δ in vascular diseases Journal article
Circulation Journal, 2013,Volume: 77,Issue: 11,Page: 2664-2671
Authors:  Cheang W.S.;  Fang X.;  Tian X.Y.
Favorite  |  View/Download:9/0  |  Submit date:2019/01/15
Atherosclerosis  Endothelial function  Peroxisome proliferator-activated receptors  Vasculature  
Genetic background controls tumor development in pten-deficient mice Journal article
CANCER RESEARCH, 2006,Volume: 66,Issue: 13,Page: 6492-6496
Authors:  Dan Freeman;  Ralf Lesche;  Nathalie Kertesz;  Shungyou Wang;  Gang Li;  Jing Gao;  Matthias Groszer;  Hilda Martinez-Diaz;  Nora Rozengurt;  George Thomas;  Xin Liu;  Hong Wu
Favorite  |  View/Download:6/0  |  Submit date:2019/01/22