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NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Miao,Kai;  Lei,Josh Haipeng;  Valecha,Monica Vishnu;  Zhang,Aiping;  Xu,Jun;  Wang,Lijian;  Lyu,Xueying;  Chen,Si;  Miao,Zhengqiang;  Zhang,Xin;  Su,Sek Man;  Shao,Fangyuan;  Rajendran,Barani Kumar;  Bao,Jiaolin;  Zeng,Jianming;  Sun,Heng;  Chen,Ping;  Tan,Kaeling;  Chen,Qiang;  Wong,Koon Ho;  Xu,Xiaoling;  Deng,Chu Xia
Favorite | View/Download:331/0 | TC[WOS]:0 TC[Scopus]:1 | Submit date:2020/09/16
A Systematic Bioinformatics Workflow With Meta-Analytics Identified Potential Pathogenic Factors of Alzheimer’s Disease Journal article
Frontiers in Neuroscience, 2020,Volume: 14
Authors:  Yuen,Sze Chung;  Zhu,Hongmei;  Leung,Siu Wai
Favorite | View/Download:1/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2020/11/06
Alzheimer’s disease  bioinformatics  meta-analysis  microarray analysis  RNA sequence analysis  
PRDM3 attenuates pancreatitis and pancreatic tumorigenesis by regulating inflammatory response Journal article
Cell Death and Disease, 2020,Volume: 11,Issue: 3
Authors:  Ye,Jie;  Huang,Anpei;  Wang,Haitao;  Zhang,Anni M.Y.;  Huang,Xiaojun;  Lan,Qingping;  Sato,Tomohiko;  Goyama,Susumu;  Kurokawa,Mineo;  Deng,Chuxia;  Sander,Maike;  Schaeffer,David F.;  Li,Wen;  Kopp,Janel L.;  Xie,Ruiyu
Favorite | View/Download:79/0 | TC[WOS]:0 TC[Scopus]:1 | Submit date:2020/09/16
BRCA1 Deficiency Impairs Mitophagy and Promotes Inflammasome Activation and Mammary Tumor Metastasis Journal article
Advanced Science, 2020,Volume: 7,Issue: 6
Authors:  Chen,Qiang;  Lei,Josh Haipeng;  Bao,Jiaolin;  Wang,Haitao;  Hao,Wenhui;  Li,Licen;  Peng,Cheng;  Masuda,Takaaki;  Miao,Kai;  Xu,Jun;  Xu,Xiaoling;  Deng,Chu Xia
Favorite | View/Download:79/0 | TC[WOS]:2 TC[Scopus]:8 | Submit date:2020/09/16
ATM-AMPK-DRP1  BRCA1  inflammasomes  mitochondrial dynamics  mitophagy  
Imaging of macrophage mitochondria dynamics in vivo reveals cellular activation phenotype for diagnosis Journal article
Theranostics, 2020,Volume: 10,Issue: 7,Page: 2897-2917
Authors:  Li,Yue;  He,Yuan;  Miao,Kai;  Zheng,Ying;  Deng,Chuxia;  Liu,Tzu Ming
Favorite | View/Download:85/0 | TC[WOS]:0 TC[Scopus]:5 | Submit date:2020/09/16
In vivo imaging  Liposome  Macrophage  Mitochondria  Multiphoton microscopy  
Stagewise keratinocyte differentiation from human embryonic stem cells by defined signal transduction modulators Journal article
International Journal of Biological Sciences, 2020,Volume: 16,Issue: 8,Page: 1450-1462
Authors:  Zhong,Hui;  Ren,Zhili;  Wang,Xiaoyan;  Miao,Kai;  Ni,Wenjun;  Meng,Ya;  Lu,Ligong;  Wang,Chunming;  Liu,Weiwei;  Deng,Chu Xia;  Xu,Ren He;  Chen,Guokai
Favorite | View/Download:72/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2020/09/16
Defined factors  Human embryonic stem cells  Keratinocyte differentiation  
Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 10,Page: 1279-1291
Authors:  Lei Fan;  Xiao-xia Qiu;  Zhi-yuan Zhu;  Jian-lu Lv;  Jian Lu;  Fei Mao;  Jin Zhu;  Jia-ying Wang;  Xiao-wei Guan;  Jing Chen;  Jin Ren;  Ji-ming Ye;  Yong-hua Zhao;  Jian Li;  Xu Shen
Favorite | View/Download:24/0 | TC[WOS]:2 TC[Scopus]:8 | Submit date:2020/04/14
App/ps1 Transgenic Mice  Alzheimer’s Disease  Autophagy  Inflammation  Nitazoxanide  
Loading of water-insoluble celastrol into niosome hydrogels for improved topical permeation and anti-psoriasis activity Journal article
Colloids and Surfaces B: Biointerfaces, 2019,Volume: 182
Authors:  Shikang Meng;  Lin Sun;  Lun Wang;  Zibei Lin;  Zeyu Liu;  Long Xi;  Zhenping Wang;  Ying Zheng
Favorite | View/Download:24/0 | TC[WOS]:3 TC[Scopus]:18 | Submit date:2020/04/08
Celastrol  Niosomes  Psoriasis  Topical Permeation  
Hydroxyurea Facilitates Manifestation of Disease Relevant Phenotypes in Patients-Derived IPSCs-Based Modeling of Late-Onset Parkinson’s Disease Journal article
AGING AND DISEASE, 2019,Volume: 10,Issue: 5,Page: 1037-1048
Authors:  Yuan Tan;  Minjing Ke;  Zhijian Huang;  Cheong-Meng Chong;  Xiaotong Cen;  Jia-Hong Lu;  Xiaoli Yao;  Dajiang Qin;  Huanxing Su
Favorite | View/Download:24/0 | TC[WOS]:2 TC[Scopus]:4 | Submit date:2020/04/08
Disease Phenotypes  Er Stress  Induced Pluripotentstem Cells  Parkinson’s Disease  Hydroxyurea  
Deciphering the Pharmacological Mechanisms of the Huayu-Qiangshen-Tongbi Formula Through Integrating Network Pharmacology and In Vitro Pharmacological Investigation Journal article
FRONTIERS IN PHARMACOLOGY, 2019,Volume: 10
Authors:  Zihao Wang;  Ke-Gang Linghu;  Yuanjia Hu;  Huali Zuo;  Hao Yi;  Shi-Hang Xiong;  Jinjian Lu;  Ging Chan;  Hua Yu;  Run-Yue Huang
Favorite | View/Download:31/0 | TC[WOS]:1 TC[Scopus]:4 | Submit date:2019/12/04
Rheumatoid Arthritis  Network Pharmacology  Traditional Chinese Medicine  Huayu-qiangshen-tongbi Formula  In Vitro Validation