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A novel Ca2+ current blocker promotes angiogenesis and cardiac healing after experimental myocardial infarction in mice Journal article
PHARMACOLOGICAL RESEARCH, 2018,Volume: 134,Page: 109-117
Authors:  Cui, Guozhen;  Xin, Qiqi;  Tseng, Hisa Hui Ling;  Hoi, Maggie PuiMan;  Wang, Yan;  Yang, Binrui;  Choi, InLeng;  Wang, Yuqiang;  Yuan, Rong;  Chen, Keji;  Cong, Weihong;  Lee, Simon MingYuen
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Cardioprotection  Angiogenesis  ADTM  Zebrafish  VEGF  
A Novel Tetramethylpyrazine Derivative Prophylactically Protects against Glutamate-Induced Excitotoxicity in Primary Neurons through the Blockage of N-Methyl-D-aspartate Receptor Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:  Hu, Shengquan;  Hu, Huihui;  Mak, Shinghung;  Cui, Guozhen;  Lee, Mingyuen;  Shan, Luchen;  Wang, Yuqiang;  Lin, Huangquan;  Zhang, Zaijun;  Han, Yifan
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Alzheimer's disease  tetramethylpyrazine derivative  NMDA receptor  neuroprotection  oxidative stress  GSK3 beta  
Potent Protection Against MPP+-Induced Neurotoxicity via Activating Transcription Factor MEF2D by a Novel Derivative of Naturally Occurring Danshensu/Tetramethylpyrazine Journal article
NeuroMolecular Medicine, 2016,Volume: 18,Issue: 4,Page: 561-572
Authors:  Hu S.;  Wang L.;  Mak S.;  Zhang Z.;  Xu D.;  Li H.;  Li Y.;  Hu Y.;  Lee S.M.Y.;  Wang Y.;  Han Y.
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Danshensu/tetramethylpyrazine derivative  GSK3β  MEF2D  MPP+  Neuroprotection  Parkinson’s disease  
A New Danshensu Derivative Protects Against 6-Hydroxydopamine-Induced Neurotoxicity in Vitro and in Vivo Journal article
American Journal of Chinese Medicine, 2016,Volume: 44,Issue: 7,Page: 1349-1361
Authors:  Cui G.;  Shan L.;  Chen Y.;  Zhou H.;  Wang Y.;  Lee S.M.-Y.
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Anti-Inflammation  Anti-Oxidation  Danshensu Derivative  Neuroprotection  
A novel agent enhances the chemotherapeutic efficacy of doxorubicin in MCF-7 breast cancer cells Journal article
Frontiers in Pharmacology, 2016,Volume: 7,Issue: AUG
Authors:  Wang L.;  Chan J.Y.;  Zhou X.;  Cui G.;  Yan Z.;  Wang L.;  Yan R.;  Di L.;  Wang Y.;  Hoi M.P.;  Shan L.;  Lee S.M.
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Breast Cancer  Danshensu  Doxorubicin  Glycolysis  Grp78 Protein  Tetramethylpyrazine  
A novel agent exerts antitumor activity in breast cancer cells by targeting mitochondrial complex II Journal article
Oncotarget, 2016,Volume: 7,Issue: 22,Page: 32054-32064
Authors:  Wang L.;  Zhang X.;  Cui G.;  Chan J.Y.-W.;  Wang L.;  Li L.;  Shan L.;  Xu C.;  Zhang Q.;  Wang Y.;  Di L.;  Lee S.M.-Y.
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Breast Cancer  Danshensu  Mitochondrial Complex Ii  Reactive Oxygen Species  Tetramethylpyrazine  
A Novel Danshensu Derivative Prevents Cardiac Dysfunction and Improves the Chemotherapeutic Efficacy of Doxorubicin in Breast Cancer Cells Journal article
Journal of Cellular Biochemistry, 2016,Volume: 117,Issue: 1,Page: 94-105
Authors:  Wang L.;  Zhang X.;  Chan J.Y.-W.;  Shan L.;  Cui G.;  Cui Q.;  Wang Y.;  Li J.;  Chen H.;  Zhang Q.;  Yu P.;  Han Y.;  Wang Y.;  Lee S.M.-Y.
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BREAST CANCER  CARDIOTOXICITY  DOXORUBICIN  MITOCHONDRIAL BIOGENESIS  
Relaxation effect of a novel Danshensu/tetramethylpyrazine derivative on rat mesenteric arteries Journal article
European Journal of Pharmacology, 2015,Volume: 761,Page: 153-160
Authors:  Li R.W.-S.;  Yang C.;  Shan L.;  Zhang Z.;  Wang Y.;  Kwan Y.W.;  Lee S.M.Y.;  Hoi M.P.M.;  Chan S.W.;  Cheung A.C.;  Cheung K.H.;  Leung G.P.H.
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Calcium channel  Danshensu tetramethylpyrazine  Mesenteric artery  Relaxation  
Identification of disulfide isomerase ERp57 as a target for small molecule cardioprotective agents Journal article
RSC Advances, 2015,Volume: 5,Issue: 91,Page: 74605-74610
Authors:  Cui G.;  Shan L.;  Chu I.K.;  Li G.;  Heng Leung G.P.;  Wang Y.;  Wa Kwan Y.;  Wan Chan S.;  Man Hoi M.P.;  Yuen Lee S.M.
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Synthesis and relationship of stability and biological activity of new DSS and TMP conjugates Journal article
MedChemComm, 2015,Volume: 6,Issue: 4,Page: 586-591
Authors:  Sun Y.;  Tan Z.;  Liang Z.;  Wang L.;  Shan L.;  Yu P.;  Lee S.M.;  Wang Y.
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