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Investigational Hypoxia-Activated Prodrugs: Making Sense of Future Development Journal article
Current Drug Targets, 2018,Volume: 20
Authors:  Min-Xia Su;  Le-Le Zhang;  Zhang-Jian Huang;  Jia-Jie Shi;  Jin-Jian Lu
Favorite  |  View/Download:5/0  |  Submit date:2019/01/14
Hypoxia-activated Prodrug  Topoisomerase Ii Inhibitors  Dna Alkylating Agents  Targeted Drugs  Reductases Activity  Patient Selection  Clinical Progress  
Influence of supramolecular encapsulation of camptothecin by cucurbit[7]uril: Reduced toxicity and preserved anti-cancer activity Journal article
MedChemComm, 2016,Volume: 7,Issue: 7,Page: 1392-1397
Authors:  Yang X.;  Wang Z.;  Niu Y.;  Chen X.;  Lee S.M.Y.;  Wang R.
Favorite  |  View/Download:8/0  |  Submit date:2018/11/06
A mechanism for 1,4-Benzoquinone-induced genotoxicity Journal article
Oncotarget, 2016,Volume: 7,Issue: 29,Page: 46433-46447
Authors:  Son M.Y.;  Deng C.-X.;  Hoeijmarkers J.H.;  Rebel V.I.;  Hasty P.
Favorite  |  View/Download:6/0  |  Submit date:2018/12/13
Double Strand Break Repair  Fanconi Anemia  Replication Fork Maintenance  Type 1 Topoisomerase  
Alkaloids Isolated from Natural Herbs as the Anticancer Agents Journal article
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2012,Issue: 4,Page: 623-644
Authors:  Lu, JJ (Lu, Jin-Jian);  Bao, JL (Bao, Jiao-Lin);  Chen, XP (Chen, Xiu-Ping);  HHuang, M (Huang, Min);  Wang, YT (Wang, Yi-Tao)
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Cell-cycle Arrest  Sanguinarine-induced Apoptosis  Suppresses Tumor-growth  Swiss Albino Mice  Matrine Inhibits Proliferation  Hepatocellular-carcinoma Cells  Mediated Multidrug-resistance  Buccal Pouch Carcinogenesis  Berberine-induced Apoptosis  Induced Lung Carcinogenesis  
Antitumor agents 294. Novel E-ring-modified camptothecin-4β-anilino- 4′-O-demethyl-epipodophyllotoxin conjugates as DNA topoisomerase i inhibitors and cytotoxic agents Journal article
Bioorganic and Medicinal Chemistry, 2012,Volume: 20,Issue: 14,Page: 4489-4494
Authors:  Ye D.;  Shi Q.;  Leung C.-H.;  Kim S.-W.;  Park S.-Y.;  Gullen E.A.;  Jiang Z.L.;  Zhu H.;  Morris-Natschke S.L.;  Cheng Y.-C.;  Lee K.-H.
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Camptothecin (CPT)  Conjugates  Cytotoxicity  Epipodophyllotoxin  Etoposide (VP-16)  Topoisomerase  
Multi-Target Drugs: The Trend of Drug Research and Development Journal article
PLOS ONE, 2012,Volume: 7,Issue: 6,Page: 30-46
Authors:  Lu, JJ (Lu, Jin-Jian);  Pan, W (Pan, Wei);  Hu, YJ (Hu, Yuan-Jia);  Wang, YT (Wang, Yi-Tao
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Cancer-therapy  Alzheimers-disease  Parkinsons-disease  Attractive Target  Natural-products  b Inhibitors  Discovery  Atherosclerosis  Acetylcholinesterase  Proliferation  
Berberine hydrochloride: anticancer activity and nanoparticulate delivery system. Journal article
International journal of nanomedicine, 2011,Volume: 6,Page: 1773-7
Authors:  Tan, Wen;  Li, Yingbo;  Chen, Meiwan;  Wang, Yitao
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Anticancer Mechanisms  Berberine Hydrochloride  Nanoparticulate Drug Progress  
Curcumin induces DNA damage and caffeine-insensitive cell cycle arrest in colorectal carcinoma HCT116 cells Journal article
Molecular and Cellular Biochemistry, 2011,Volume: 354,Issue: 1-2,Page: 247-252
Authors:  Lu J.-J.;  Cai Y.-J.;  Ding J.
Favorite  |  View/Download:2/0  |  Submit date:2018/12/28
Caffeine  Curcumin  Dna Damage  Mitosis Arrest  s Phase Arrest  Tubulin  
Cyclometalated platinum(ii) complexes as topoisomerase IIα poisons Journal article
Chemical Communications, 2011,Volume: 47,Issue: 2,Page: 719-721
Authors:  Liu J.;  Leung C.-H.;  Chow A.L.-F.;  Sun R.W.-Y.;  Yan S.-C.;  Che C.-M.
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Organoplatinum(II) complexes with nucleobase motifs as inhibitors of human topoisomerase II catalytic activity Journal article
Chemistry - An Asian Journal, 2010,Volume: 5,Issue: 10,Page: 2271-2280
Authors:  Wang P.;  Leung C.-H.;  Ma D.-L.;  Lu W.;  Che C.-M.
Favorite  |  View/Download:2/0  |  Submit date:2018/11/06
Cancer  DNA  Inhibitors  Nucleobases  Platinum