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Cucurbitacin B suppresses metastasis mediated by reactive oxygen species (ROS) via focal adhesion kinase (FAK) in breast cancer MDA-MB-231 cells Journal article
CHINESE JOURNAL OF NATURAL MEDICINES, 2018,Volume: 16,Issue: 1,Page: 10-19
Authors:  Luo Wei-Wei;  Zhao Wen-Wen;  Lu Jin-Jian;  Wang Yi-Tao;  Chen Xiu-Ping
Favorite  |  View/Download:19/0  |  Submit date:2018/10/30
Cucurbitacin b  Metastasis  Ros  Fak  Breast Cancer  
Ethanol enhances cucurbitacin B-induced apoptosis by inhibiting cucurbitacin B-induced autophagy in LO2 hepatocytes Journal article
Molecular and Cellular Toxicology, 2016,Volume: 12,Issue: 1,Page: 29-36
Authors:  Ding Q.;  Bao J.;  Zhao W.;  Lu J.;  Zhu H.;  Chen X.
Favorite  |  View/Download:1/0  |  Submit date:2018/12/28
Apoptosis  Autophagy  Cucurbitacin b  Ethanol  Hepatocyte  
Cucurbitacin B inhibits proliferation, induces G2/M cycle arrest and autophagy without affecting apoptosis but enhances MTT reduction in PC12 cells Journal article
Bangladesh Journal of Pharmacology, 2016,Volume: 11,Issue: 1,Page: 110-118
Authors:  Wu C.;  Bao J.;  He C.;  Lu J.;  Chen X.
Favorite  |  View/Download:2/0  |  Submit date:2018/12/28
Apoptosis  Autophagy  Cucurbitacin b  G2/m Cycle  Mtt  Pc12 Cell  
PTEN activation by DNA damage induces protective autophagy in response to Cucurbitacin B in hepatocellular carcinoma cells Journal article
Oxidative Medicine and Cellular Longevity, 2016,Volume: 2016
Authors:  Niu Y.;  Sun W.;  Lu J.-J.;  Ma D.-L.;  Leung C.-H.;  Pei L.;  Chen X.
Favorite  |  View/Download:6/0  |  Submit date:2018/11/06
Cucurbitacin e induces caspase-dependent apoptosis and protective autophagy mediated by ROS in lung cancer cells Journal article
Chemico-Biological Interactions, 2016,Volume: 253,Page: 1
Authors:  Ma G.;  Luo W.;  Lu J.;  Ma D.-L.;  Leung C.-H.;  Wang Y.;  Chen X.
Favorite  |  View/Download:2/0  |  Submit date:2018/10/31
Apoptosis  Autophagy  Cancer  Cucurbitacin e  Reactive Oxygen Species  
Cucurbitacin B induces DNA damage and autophagy mediated by reactive oxygen species (ROS) in MCF-7 breast cancer cells Journal article
Journal of Natural Medicines, 2015,Volume: 69,Issue: 4,Page: 522-530
Authors:  Ren G.;  Sha T.;  Guo J.;  Li W.;  Lu J.;  Chen X.
Favorite  |  View/Download:4/0  |  Submit date:2018/12/28
Autophagy  Breast Cancer  Cucurbitacin b  Dna Damage  Ros  
Cucurbitacins: A Systematic Review of the Phytochemistry and Anticancer Activity Journal article
American Journal of Chinese Medicine, 2015,Volume: 43,Issue: 7,Page: 1331-1350
Authors:  Cai Y;  Fang XF;  He CW;  Li P;  Xiao F;  Wang YT;  Chen MW
Favorite  |  View/Download:6/0  |  Submit date:2018/11/27
Cucurbitacins  Phytochemistry  Anticancer  Mechanism  
Cucurbitacin B induces DNA damage, G2/M phase arrest, and apoptosis mediated by reactive oxygen species (ROS) in leukemia K562 cells Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2014,Volume: 14,Issue: 8,Page: 1146-1153
Authors:  Guo J.;  Zhao W.;  Hao W.;  Ren G.;  Lu J.;  Chen X.
Favorite  |  View/Download:2/0  |  Submit date:2018/12/28
Apoptosis  Cancer  Cucurbitacin b  Dna Damage  G2/m Arrest  Ros  
Cucurbitacin B induced ATM-mediated DNA damage causes G2/M cell cycle arrest in a ROS-dependent manner Journal article
PLoS ONE, 2014,Volume: 9,Issue: 2
Authors:  Guo J.;  Wu G.;  Bao J.;  Hao W.;  Lu J.;  Chen X.
Favorite  |  View/Download:4/0  |  Submit date:2018/10/30