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Regulation of human pregnane X receptor and its target gene cytochrome P450 3A by praeruptorin a isolated from the herbal medicine peucedanum praeruptorum Journal article
Planta Medica, 2013,Volume: 79,Issue: 16,Page: 1509-1515
Authors:  Huang L.;  Bi H.-C.;  Li Y.-H.;  Zhang J.-Q.;  Kuang S.-Y.;  Zhang L.;  Wang Y.-T.;  Huang M.
Favorite  |  View/Download:5/0  |  Submit date:2018/11/06
Apiaceae  cytochrome P450 3A  herb-drug interaction  Peucedanum praeruptorum  praeruptorin A  pregnane X receptor  
SRC-3 is required for CAR-regulated hepatocyte proliferation and drug metabolism Journal article
JOURNAL OF HEPATOLOGY, 2012,Volume: 56,Issue: 1,Page: 210-217
Authors:  Tenghui Chen;  Qiang Chen;  Yixiang Xu;  Qiling Zhou;  Jingwei Zhu;  Hao Zhang;  Qiao Wu;  Jianming Xu;  Chundong Yu
Favorite  |  View/Download:3/0  |  Submit date:2019/01/22
Src-3  Car  Hepatocyte Proliferation  Drug Metabolism  
Regulation of human pregnane X receptor and its target gene cytochrome P450 3A4 by Chinese herbal compounds and a molecular docking study Journal article
XENOBIOTICA, 2011,Volume: 41,Issue: 4,Page: 259-280
Authors:  Liu, YH (Liu, Ya-He);  Mo, SL (Mo, Sui-Lin);  Bi, HC (Bi, Hui-Chang);  Hu, BF (Hu, Bing-Fang);  Li, CG (Li, Chun Guang);  Wang, YT (Wang, Yi-Tao);  Huang, L (Huang, Ling);  Huang, M (Huang, Min);  Duan, W (Duan, Wei);  Liu, JP (Liu, Jun-Ping);  Wei, MQ (Wei, Ming Qian);  Zhou, SF (Zhou, Shu-Feng)
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Constitutive Androstane Receptor  Primary Human Hepatocytes  Corepressor Silencing-mediator  Hepatoma-cell Lines  Human Cyp3a4 Gene  Nuclear Receptor  Drug-metabolism  Transcriptional Activation  Xenobiotic Receptor  Interindividual Variability  
CAR-mediated Up-regulation of CYP3A4 Expression in LS174T Cells by Chinese Herbal Compounds Journal article
DRUG METABOLISM AND PHARMACOKINETICS, 2011,Volume: 26,Issue: 4,Page: 331-340
Authors:  Huang, Ling;  Bi, Hui-Chang;  Liu, Ya-He;  Wang, Yi-Tao;  Xue, Xin-Ping;  Huang, Min
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Constitutive Androstane Receptor (Car)  Cytochrome P450 3a4  Induction  Herb Compounds  Herb-drug Interaction