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Targeting AURKA-CDC25C axis to induce synthetic lethality in ARID1A-deficient colorectal cancer cells Journal article
NATURE COMMUNICATIONS, 2018,Volume: 9
Authors:  Wu, Changjie;  Lyu, Junfang;  Yang, Eun Ju;  Liu, Yifan;  Zhang, Baoyuan;  Shim, Joong Sup
Favorite  |  View/Download:23/0  |  Submit date:2018/10/30
Physalin B induces cell cycle arrest and triggers apoptosis in breast cancer cells through modulating p53-dependent apoptotic pathway Journal article
BIOMEDICINE & PHARMACOTHERAPY, 2018,Volume: 101,Page: 334-341
Authors:  Wang, Anqi;  Wang, Shengpeng;  Zhou, Fayang;  Li, Peng;  Wang, Yitao;  Gan, Lishe;  Lin, Ligen
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Physalin b  Breast Cancer  Cell Cycle  Apoptosis  P53  Akt  
Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B Journal article
NEUROPHARMACOLOGY, 2017,Volume: 126,Page: 12-24
Authors:  Guo, Baojian;  Hu, Shengquan;  Zheng, Chengyou;  Wang, Hongyu;  Luo, Fangcheng;  Li, Haitao;  Cui, Wei;  Yang, Xifei;  Cui, Guozhen;  Mak, Shinghung;  Choi, Tony Chung-Lit;  Ma, Edmond Dik-Lung;  Wang, Yuqiang;  Lee, Simon Ming Yuen;  Zhang, Zaijun;  Han, Yifan
View  |  Adobe PDF(2766Kb)  |  Favorite  |  View/Download:360/8  |  Submit date:2018/10/31
Parkinson's disease  SU4312  Neuroprotection  Myocyte enhancer factor 2D  Monoamine oxidase-B  
Genome-wide methylome and chromatin interactome identify abnormal enhancer to be risk factor of breast cancer Journal article
ONCOTARGET, 2017,Volume: 8,Issue: 27,Page: 44705-44719
Authors:  Wang, Yuan;  Hao, Da-Peng;  Li, Jing-Jing;  Wang, Li;  Di, Li-Jun
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Enhancer Methylation  Breast Cancer  Chromatin Interaction  Polii Chia-pet  Gene Regulation  
Structure of the cohesin loader Scc2 Journal article
Nature Communications, 2017
Authors:  William C. H. Chao;  Yasuto Murayama;  Sofía Muñoz;  Andrew W. Jones;  Benjamin O. Wade;  Andrew G. Purkiss;  Xiao-Wen Hu;  Aaron Borg;  Ambrosius P. Snijders;  Frank Uhlmann;  Martin R. Singleton
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Role of nuclear factor of activated T-cells 5 in regulating hypertonic-mediated secretin receptor expression in kidney collecting duct cells Journal article
Biochimica et Biophysica Acta - Gene Regulatory Mechanisms, 2016,Volume: 1859,Issue: 7,Page: 922-932
Authors:  Chua O.W.H.;  Wong K.K.L.;  Ko B.C.;  Chung S.K.;  Chow B.K.C.;  Lee L.T.O.
Favorite  |  View/Download:3/0  |  Submit date:2019/01/15
Hypertonicity  Nuclear factor of activated T-cells 5  Osmoregulation  Secretin receptor  Transcriptional regulation  
An iridium(III)-based irreversible protein-protein interaction inhibitor of BRD4 as a potent anticancer agent Journal article
Chemical Science, 2015,Volume: 6,Issue: 10,Page: 5400
Authors:  Zhong H.-J.;  Lu L.;  Leung K.-H.;  Wong C.C.L.;  Peng C.;  Yan S.-C.;  Ma D.-L.;  Cai Z.;  David Wang H.-M.;  Leung C.-H.
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Estrogen receptor-mediated long-range chromatin interactions and transcription in breast cancer Journal article
Molecular and Cellular Endocrinology, 2014,Volume: 382,Issue: 1,Page: 624-632
Authors:  Mei Hui Liu;  Edwin Cheung
Favorite  |  View/Download:6/0  |  Submit date:2018/12/19
Long-range Chromatin Interaction  Chia-pet  3c  Distal Regulation  Estrogen Receptor-a  
Simultaneously learning dna motif along with its position and sequence rank preferences through expectation maximization algorithm Journal article
Journal of Computational Biology, 2013,Volume: 20,Issue: 3,Page: 237-248
Authors:  Zhang Z.;  Chang C.W.;  Hugo W.;  Cheung E.;  Sung W.-K.
Favorite  |  View/Download:2/0  |  Submit date:2018/12/17
binding preference  expectation maximization  importance sampling  motif finding.  
Hepatitis B virus X protein stabilizes amplified in breast cancer 1 protein and cooperates with it to promote human hepatocellular carcinoma cell invasiveness Journal article
Hepatology, 2012,Volume: 56,Issue: 3,Page: 1015-1024
Authors:  Liu Y.;  Tong Z.;  Li T.;  Chen Q.;  Zhuo L.;  Li W.;  Wu R.-C.;  Yu C.
Favorite  |  View/Download:4/0  |  Submit date:2019/01/16