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The metabolic footprint during adipocyte commitment highlights ceramide modulation as an adequate approach for obesity treatment Journal article
EBioMedicine, 2020,Volume: 51
Authors:  Hou,Weilong;  Chen,Qiang;  Wang,Haitao;  Qiu,Pengxiang;  Lyu,Xueying;  Chen,Weiping;  Chua,Melvin L.K.;  Chinn,Y. Eugene;  Deng,Chu Xia;  Wang,Ruihong
Favorite | View/Download:73/0 | TC[WOS]:0 TC[Scopus]:1 | Submit date:2020/09/16
Adipogenesis  Apoptosis  Ceramide  Epigenetic modification  Metabolic landscape  Metabolomics  Obesity  
Rmrp Mutation Disrupts Chondrogenesis and Bone Ossification in Zebrafish Model of Cartilage-Hair Hypoplasia via Enhanced Wnt/β-Catenin Signaling Journal article
Journal of Bone and Mineral Research, 2019,Volume: 34,Issue: 11,Page: 2101-2116
Authors:  Sun,Xianding;  Zhang,Ruobin;  Liu,Mi;  Chen,Hangang;  Chen,Liang;  Luo,Fengtao;  Zhang,Dali;  Huang,Junlan;  Li,Fangfang;  Ni,Zhenhong;  Qi,Huabing;  Su,Nan;  Jin,Min;  Yang,Jing;  Tan,Qiaoyan;  Du,Xiaolan;  Chen,Bo;  Huang,Haiyang;  Chen,Shuai;  Yin,Liangjun;  Xu,Xiaoling;  Deng,Chuxia;  Luo,Lingfei;  Xie,Yangli;  Chen,Lin
Favorite | View/Download:73/0 | TC[WOS]:2 TC[Scopus]:3 | Submit date:2020/09/16
CARTILAGE-HAIR HYPOPLASIA  RMRP  SKELETAL DEVELOPMENT  WNT/Β-CATENIN  ZEBRAFISH  
A novel dual sensitive polymer-gambogic acid conjugate: synthesis, characterization, and in vitro evaluation Journal article
NANOTECHNOLOGY, 2019,Volume: 30,Issue: 50
Authors:  Ke Song;  Zhaobo Wang;  Xue Liu;  Guolin Zhang;  Xin Wang;  DeFang Ouyang;  Mingrui Guo;  Lijiang Chen
Favorite | View/Download:13/0 | TC[WOS]:3 TC[Scopus]:0 | Submit date:2020/03/25
Polymer-drug Conjugate  Gambogic Acid  Sensitive Drug Delivery  Cathepsin b  Glutathione  
Metformin protects PC12 cells and hippocampal neurons from H2O (2)-induced oxidative damage through activation of AMPK pathway Journal article
JOURNAL OF CELLULAR PHYSIOLOGY, 2019,Volume: 234,Issue: 9,Page: 16619-16629
Authors:  Xia Zhao;  Zhiwen Zeng;  Uma Gaur;  Jiankang Fang;  Tangming Peng;  Shuai Li;  Wenhua Zheng
Favorite | View/Download:10/0 | TC[WOS]:8 TC[Scopus]:0 | Submit date:2020/06/11
Aging  Amp-activated Protein Kinase  Hydrogen Peroxide  Metformin  Pc12 Cells  
Nuclear localization of Desmoplakin and its involvement in telomere maintenance Journal article
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2019,Volume: 15,Issue: 11,Page: 2350-2362
Authors:  Peipei Li;  Yuan Meng;  Yuan Wang;  Jingjing Li;  Manting Lam;  Li Wang;  Li-jun Di
Favorite | View/Download:14/0 | TC[WOS]:1 TC[Scopus]:0 | Submit date:2020/05/21
Crispr Bioid Telomere Dsp  
Insulin Stimulates PI3K/AKT and Cell Adhesion to Promote the Survival of Individualized Human Embryonic Stem Cells Journal article
STEM CELLS, 2019,Volume: 37,Issue: 8,Page: 1030-1041
Authors:  Carlos Godoy‐Parejo;  Chunhao Deng;  Weiwei Liu;  Guokai Chen
Favorite | View/Download:15/0 | TC[WOS]:3 TC[Scopus]:0 | Submit date:2020/05/21
Hesc  Cell Survival  Cell Adhesion  Focal Adhesion  Niche  Individualization  Insulin  Integrin  Caspase  Igf  Akt  
A Danshensu-Tetramethylpyrazine Conjugate DT-010 Overcomes Multidrug Resistance in Human Breast Cancer Journal article
FRONTIERS IN PHARMACOLOGY, 2019,Volume: 10
Authors:  Xinhua Zhou;  Anqi Wang;  Liang Wang;  Jianhua Yin;  Li Wang;  Lijun Di;  Maggie Pui-Man Hoi;  Luchen Shan;  Xu Wu;  Yuqiang Wang
Favorite | View/Download:12/0 | TC[WOS]:2 TC[Scopus]:0 | Submit date:2020/05/21
Danshensu  Tetramethylpyrazine  Breast Cancer  Resistance  Glycolysis  P-glycoprotein  
Yinchenhao decoction suppresses rat liverfibrosis involved in an apoptosisregulation mechanism based on network pharmacology and transcriptomicanalysis Journal article
Biomedicine & Pharmacotherapy, 2019,Volume: 114
Authors:  Fei-Fei Cai;  Yan-Qin Bian;  Rong Wu;  Yang Sun;  Xiao-Le Chen;  Meng-Die Yang;  Qian-ru Zhang;  Yuanjia Hu;  Ming-Yu Sun;  Shi-Bing Su
Favorite | View/Download:3/0 | TC[WOS]:17 TC[Scopus]:0 | Submit date:2020/10/23
Yinchenhao Decoction  Liver Fibrosis  Network Pharmacology  Transcriptomics  Apoptosis  
Flaxseed extract induces apoptosis in human breast cancer MCF-7 cells Journal article
Food and Chemical Toxicology, 2019,Volume: 127,Page: 188-196
Authors:  Tingyan Hu;  Kegang Linghu;  Siqi Huang;  Maurizio Battino;  Milen I. Georgiev;  Gokhan Zengin;  Defang Li;  Yun Deng;  Y.T. Wang;  Hui Cao
Favorite | View/Download:18/0 | TC[WOS]:3 TC[Scopus]:0 | Submit date:2020/03/27
Flaxseed  Mcf-7 cells  Apoptosis  Ros  Mitochondrial Membrane Potential  Dietary Supplement  
Synthesis and biological evaluation of aza-crown ether–squaramide conjugates as anion/cation symporters Journal article
FUTURE MEDICINAL CHEMISTRY, 2019,Volume: 11,Issue: 10,Page: 1091-1106
Authors:  Xi-Hui Yu;  Xiong-Jie Cai;  Xiao-Qiao Hong;  Kin Yip Tam;  Kun Zhang;  Wen-Hua Chen
Favorite | View/Download:20/0 | TC[WOS]:2 TC[Scopus]:0 | Submit date:2020/05/21