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Toosendanin, a natural product, inhibited TGF-1-induced epithelial-mesenchymal transition through ERK/Snail pathway Journal article
PHYTOTHERAPY RESEARCH, 2018,Volume: 32,Issue: 10,Page: 2009-2020
Authors:  Luo, Weiwei;  Liu, Xin;  Sun, Wen;  Lu, Jin-Jian;  Wang, Yitao;  Chen, Xiuping
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Emt  Erk1/2  Snail  Lung Cancer  Toosendanin  
Synchronous Chemoradiation Nanovesicles by X-Ray Triggered Cascade of Drug Release Journal article
Angewandte Chemie - International Edition, 2018,Volume: 57,Issue: 28,Page: 8463-8467
Authors:  Zhou Z.;  Chan A.;  Wang Z.;  Huang X.;  Yu G.;  Jacobson O.;  Wang S.;  Liu Y.;  Shan L.;  Dai Y.;  Shen Z.;  Lin L.;  Chen W.;  Chen X.
Favorite  |  View/Download:3/0  |  Submit date:2019/01/15
Cancer Therapy  Chemoradiation  Drug Release  Nanovesicles  Oxidation Responsive  
Physalin B induces cell cycle arrest and triggers apoptosis in breast cancer cells through modulating p53-dependent apoptotic pathway Journal article
BIOMEDICINE & PHARMACOTHERAPY, 2018,Volume: 101,Page: 334-341
Authors:  Wang, Anqi;  Wang, Shengpeng;  Zhou, Fayang;  Li, Peng;  Wang, Yitao;  Gan, Lishe;  Lin, Ligen
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Physalin b  Breast Cancer  Cell Cycle  Apoptosis  P53  Akt  
Toxic Reactive Oxygen Species Enhanced Synergistic Combination Therapy by Self-Assembled Metal-Phenolic Network Nanoparticles Journal article
Advanced Materials, 2018,Volume: 30,Issue: 8
Authors:  Dai Y.;  Yang Z.;  Cheng S.;  Wang Z.;  Zhang R.;  Zhu G.;  Wang Z.;  Yung B.C.;  Tian R.;  Jacobson O.;  Xu C.;  Ni Q.;  Song J.;  Sun X.;  Niu G.;  Chen X.
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Combination Therapy  Metal-polyphenol Networks  Positron Emission Tomography  Reactive Oxygen Species  Self-assembly  
Hypochlorous Acid Promoted Platinum Drug Chemotherapy by Myeloperoxidase-Encapsulated Therapeutic Metal Phenolic Nanoparticles Journal article
ACS Nano, 2018,Volume: 12,Issue: 1,Page: 455-463
Authors:  Dai Y.;  Cheng S.;  Wang Z.;  Zhang R.;  Yang Z.;  Wang J.;  Yung B.C.;  Wang Z.;  Jacobson O.;  Xu C.;  Ni Q.;  Yu G.;  Zhou Z.;  Chen X.
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Cisplatin  Hypochlorous Acid (Hocl)  Metal-polyphenol Networks  Myeloperoxidase (Mpo)  Positron Emission Tomography  
Hybrid Nanomedicine Fabricated from Photosensitizer‐Terminated Metal–Organic Framework Nanoparticles for Photodynamic Therapy and Hypoxia‐Activated Cascade Chemotherapy Journal article
small, 2018,Volume: 15,Issue: 4
Authors:  Zhimei He;  Yunlu Dai;  Xiangli Li;  Dan Guo;  Yijing Liu;  Xiaolin Huang;  Jingjing Jiang;  Sheng Wang;  Guizhi Zhu;  Fuwu Zhang;  Lisen Lin;  Jun‐Jie Zhu;  Guocan Yu;  Xiaoyuan Chen
Favorite  |  View/Download:2/0  |  Submit date:2019/01/28
Banoxantrone  Cascade Therapy  Hypoxia‐activated Prodrugs  Nanoscale Metal–organic Frameworks  Photodynamic Therapy  
Anti-tumor effects of a 'human & mouse cross-reactive' anti-ADAM17 antibody in a pancreatic cancer model in vivo Conference paper
Authors:  Ye, Jie;  Yuen, Shun Ming;  Murphy, Gillian;  Xie, Ruiyu;  Kwok, Hang Fai
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Pancreatic ductal adenocarcinoma (PDAC)  ADAM17  Inhibitory antibody  Tumorigenesis  Targeted therapy  
Anti-tumor effects of a ‘human & mouse cross-reactive’ anti-ADAM17 antibody in a pancreatic cancer model in vivo Journal article
European Journal of Pharmaceutical Sciences, 2017,Volume: 110,Page: 62-69
Authors:  Ye J.;  Yuen S.M.;  Murphy G.;  Xie R.;  Kwok H.F.
Favorite  |  View/Download:2/0  |  Submit date:2018/12/19
Adam17  Inhibitory Antibody  Pancreatic Ductal Adenocarcinoma (Pdac)  Targeted Therapy  Tumorigenesis  
Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B Journal article
NEUROPHARMACOLOGY, 2017,Volume: 126,Page: 12-24
Authors:  Guo, Baojian;  Hu, Shengquan;  Zheng, Chengyou;  Wang, Hongyu;  Luo, Fangcheng;  Li, Haitao;  Cui, Wei;  Yang, Xifei;  Cui, Guozhen;  Mak, Shinghung;  Choi, Tony Chung-Lit;  Ma, Edmond Dik-Lung;  Wang, Yuqiang;  Lee, Simon Ming Yuen;  Zhang, Zaijun;  Han, Yifan
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Parkinson's disease  SU4312  Neuroprotection  Myocyte enhancer factor 2D  Monoamine oxidase-B  
Garcinone E induces apoptosis and inhibits migration and invasion in ovarian cancer cells Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Xu, Xiao-Huang;  Liu, Qian-Yu;  Li, Ting;  Liu, Jian-Lin;  Chen, Xin;  Huang, Li;  Qiang, Wen-An;  Chen, Xiuping;  Wang, Yitao;  Lin, Li-Gen;  Lu, Jin-Jian
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