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Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 9,Page: 1193-1204
Authors:  Ting-ting Zhou;  Tong Zhao;  Fei Ma;  Yi-nan Zhang;  Jing Jiang;  Yuan Ruan;  Qiu-ying Yan;  Gai-hong Wang;  Jin Ren;  Xiao-wei Guan;  Jun Guo;  Yong-hua Zhao;  Ji-ming Ye;  Li-hong Hu;  Jing Chen;  Xu Shen
Favorite | View/Download:15/0 | TC[WOS]:1 TC[Scopus]:1 | Submit date:2020/04/14
Type 2 Diabetes Mellitus  Hepatic Gluconeogenesis  Ampk Signaling Pathway  (e)-3-(2-(Quinoline-4-yl)Vinyl)-1h-indol-6-ol (Qvo)  4-[2-(1h-indol-3-yl)Vinyl]Quinoline (Ivq)  Prodrug  
Inhibitory effects of betulinic acid on LPS-induced neuroinflammation involve M2 microglial polarization via CaMKKβ-dependent AMPK activation Journal article
Frontiers in Molecular Neuroscience, 2018,Volume: 11
Authors:  Li C.;  Zhang C.;  Zhou H.;  Feng Y.;  Tang F.;  Hoi M.P.M.;  He C.;  Ma D.;  Zhao C.;  Lee S.M.Y.
Favorite | View/Download:13/0 | TC[WOS]:27 TC[Scopus]:27 | Submit date:2018/11/06
AMP-activated protein kinase  Betulinic acid  Calmodulin-dependent protein kinase β  Microglia polarization  Neuroinflammation  
Inhibitory Effects of Betulinic Acid on LPS-Induced Neuroinflammation Involve M2 Microglial Polarization via CaMKK beta-Dependent AMPK Activation Journal article
FRONTIERS IN MOLECULAR NEUROSCIENCE, 2018,Volume: 11
Authors:  Li, Chuwen;  Zhang, Chao;  Zhou, Hefeng;  Feng, Yu;  Tang, Fan;  Hoi, Maggie P. M.;  He, Chengwei;  Ma, Dan;  Zhao, Chao;  Lee, Simon M. Y.
Favorite | View/Download:45/0 | TC[WOS]:27 TC[Scopus]:27 | Submit date:2018/10/30
Amp-activated Protein Kinase  Betulinic Acid  Calmodulin-dependent Protein Kinase Beta  Microglia Polarization  Neuroinflammation  
GLUT12 promotes prostate cancer cell growth and is regulated by androgens and CaMKK2 signaling Journal article
ENDOCRINE-RELATED CANCER, 2018,Volume: 25,Issue: 4,Page: 453-469
Authors:  White, Mark A.;  Tsouko, Efrosini;  Lin, Chenchu;  Rajapakshe, Kimal;  Spencer, Jeffrey M.;  Wilkenfeld, Sandi R.;  Vakili, Sheiva S.;  Pulliam, Thomas L.;  Awad, Dominik;  Nikolos, Fotis;  Katreddy, Rajasekhara Reddy;  Kaipparettu, Benny Abraham;  Sreekumar, Arun;  Zhang, Xiaoliu;  Cheung, Edwin;  Coarfa, Cristian;  Frigo, Daniel E.
Favorite | View/Download:18/0 | TC[WOS]:17 TC[Scopus]:19 | Submit date:2018/10/30
GLUT12  SLC2A12  glucose metabolism  androgen receptor (AR)  calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2)  5 '-AMP-activated protein kinase (AMPK)  prostate cancer  
AMPK is involved in mediation of erythropoietin influence on metabolic activity and reactive oxygen species production in white adipocytes Journal article
International Journal of Biochemistry and Cell Biology, 2014,Volume: 54,Page: 1-9
Authors:  Wang L.;  Di L.;  Noguchi C.T.
Favorite | View/Download:8/0 | TC[WOS]:185 TC[Scopus]:16 | Submit date:2018/12/21
Adipocytes  Amp-activated Protein Kinase  Erythropoietin  Oxidative Metabolism  Reactive Oxygen Species