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BRCA1 Deficiency Impairs Mitophagy and Promotes Inflammasome Activation and Mammary Tumor Metastasis Journal article
Advanced Science, 2020,Volume: 7,Issue: 6
Authors:  Chen,Qiang;  Lei,Josh Haipeng;  Bao,Jiaolin;  Wang,Haitao;  Hao,Wenhui;  Li,Licen;  Peng,Cheng;  Masuda,Takaaki;  Miao,Kai;  Xu,Jun;  Xu,Xiaoling;  Deng,Chu Xia
Favorite | View/Download:74/0 | TC[WOS]:2 TC[Scopus]:6 | Submit date:2020/09/16
ATM-AMPK-DRP1  BRCA1  inflammasomes  mitochondrial dynamics  mitophagy  
Structure-Based Discovery of a Selective KDM5A Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines Journal article
CANCERS, 2019,Volume: 11,Issue: 1
Authors:  Yang, GJ;  Ko, CN;  Zhong, HJ;  Leung, CH;  Ma, DL
Favorite | View/Download:13/0 | TC[WOS]:7 TC[Scopus]:8 | Submit date:2020/03/24
Cell Cycle Arrest  Kdm5a  Jumonji Domain  Histone Demethylation  Protein-protein Interaction  Virtual Screening  Breast Cancer  Cell Senescence  
The expression of ubiquitin-specific peptidase 8 and its prognostic role in patients with breast cancer Journal article
Journal of Cellular Biochemistry, 2018,Volume: 119,Issue: 12,Page: 10051-10058
Authors:  Qiu H.;  Kong J.;  Cheng Y.;  Li G.
Favorite | View/Download:19/0 | TC[WOS]:2 TC[Scopus]:3 | Submit date:2019/01/15
breast cancer  clinical prognosis  ubiquitin-specific peptidase 8  
MnSOD mediates shear stress-promoted tumor cell migration and adhesion Journal article
FREE RADICAL BIOLOGY AND MEDICINE, 2018,Volume: 129,Page: 46-58
Authors:  Ma, Shijun;  Fu, Afu;  Lim, Sierin;  Chiew, Geraldine Giap Ying;  Luo, Kathy Qian
Favorite | View/Download:18/0 | TC[WOS]:5 TC[Scopus]:7 | Submit date:2019/01/17
Shear stress  Tumor cell adhesion  Tumor cell migration  Reactive oxygen species  MnSOD  FAK  
Pharmacological Inhibition of LSD1 for Cancer Treatment Journal article
MOLECULES, 2018,Volume: 23,Issue: 12
Authors:  Yang, Guan-Jun;  Lei, Pui-Man;  Wong, Suk-Yu;  Ma, Dik-Lung;  Leung, Chung-Hang
Favorite | View/Download:25/0 | TC[WOS]:17 TC[Scopus]:27 | Submit date:2019/01/17
Lsd1  Demethylase  Histone  Breast Cancer  Prostate Cancer  Acute Myeloid Leukemia  Cancer Therapy  
CtBP promotes metastasis of breast cancer through repressing cholesterol and activating TGF-beta signaling Journal article
ONCOGENE, 2018,Volume: 38,Issue: 12,Page: 2076-2091
Authors:  Zhiqiang Zhao;  Dapeng Hao;  Li Wang;  Jingjing Li;  Yuan Meng;  Peipei Li;  Yuan Wang;  Chao Zhang;  Haisheng Zhou;  Kevin Gardner;  Li-jun Di
Favorite | View/Download:14/0 | TC[WOS]:7 TC[Scopus]:12 | Submit date:2020/05/21
Fluidic shear stress increases the anti-cancer effects of ROS-generating drugs in circulating tumor cells Journal article
BREAST CANCER RESEARCH AND TREATMENT, 2018,Volume: 172,Issue: 2,Page: 297-312
Authors:  Regmi S;  Fung TS;  Lim S;  Luo KQ
Favorite | View/Download:23/0 | TC[WOS]:3 TC[Scopus]:5 | Submit date:2018/10/30
Circulating Tumor Cells  Shear Stress  Reactive Oxygen Species  Apoptosis  Anti-cancer Drugs  Doxorubicin  
Toosendanin, a natural product, inhibited TGF-1-induced epithelial-mesenchymal transition through ERK/Snail pathway Journal article
PHYTOTHERAPY RESEARCH, 2018,Volume: 32,Issue: 10,Page: 2009-2020
Authors:  Luo, Weiwei;  Liu, Xin;  Sun, Wen;  Lu, Jin-Jian;  Wang, Yitao;  Chen, Xiuping
View | Adobe PDF | Favorite | View/Download:836/43 | TC[WOS]:4 TC[Scopus]:11 | Submit date:2018/10/30
Emt  Erk1/2  Snail  Lung Cancer  Toosendanin  
Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2018,Volume: 26,Issue: 18,Page: 5053-5061
Authors:  Chen, Shao-Ru;  Li, Feng;  Ding, Mo-Yu;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Zhou, Guo-Chun;  Wang, Ying
View | Adobe PDF | Favorite | View/Download:1323/88 | TC[WOS]:3 TC[Scopus]:5 | Submit date:2018/10/30
Andrographolide  Stat3 Inhibitor  Acute Liver Damage  Inflammation  
Physalin B induces cell cycle arrest and triggers apoptosis in breast cancer cells through modulating p53-dependent apoptotic pathway Journal article
BIOMEDICINE & PHARMACOTHERAPY, 2018,Volume: 101,Page: 334-341
Authors:  Wang, Anqi;  Wang, Shengpeng;  Zhou, Fayang;  Li, Peng;  Wang, Yitao;  Gan, Lishe;  Lin, Ligen
View | Adobe PDF | Favorite | View/Download:530/20 | TC[WOS]:9 TC[Scopus]:12 | Submit date:2018/10/30
Physalin b  Breast Cancer  Cell Cycle  Apoptosis  P53  Akt