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Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 10,Page: 1279-1291
Authors:  Lei Fan;  Xiao-xia Qiu;  Zhi-yuan Zhu;  Jian-lu Lv;  Jian Lu;  Fei Mao;  Jin Zhu;  Jia-ying Wang;  Xiao-wei Guan;  Jing Chen;  Jin Ren;  Ji-ming Ye;  Yong-hua Zhao;  Jian Li;  Xu Shen
Favorite  |  View/Download:12/0  |  Submit date:2020/04/14
App/ps1 Transgenic Mice  Alzheimer’s Disease  Autophagy  Inflammation  Nitazoxanide  
Deficiency of macrophage migration inhibitory factor attenuates tau hyperphosphorylation in mouse models of Alzheimer's disease Journal article
Journal of Neuroinflammation, 2015,Volume: 12,Issue: 1
Authors:  Li S.-Q.;  Yu Y.;  Han J.-Z.;  Wang D.;  Liu J.;  Qian F.;  Fan G.-H.;  Bucala R.;  Ye R.D.
Favorite  |  View/Download:4/0  |  Submit date:2018/11/07
Alzheimer's disease  Astrocyte activation  Macrophage migration inhibitory factor  Tau phosphorylation  
Animal models for Alzheimer’sdisease: a focused review of transgenic rodent models and behavioral assessment methods Journal article
ADMET & DMPK, 2015,Volume: 3,Issue: 3,Page: 242-253
Authors:  Xiaoli Wu;  Jing Li;  Wei Zhou;  Kin Tam
Favorite  |  View/Download:2/0  |  Submit date:2019/01/07
Neurodegeneration  Transgenic Mice  Behavioural Alteration  Morris Water Maze  Radial Arm Water Maze  Cognitive Impairmen  
Huperzine a alleviates synaptic deficits and modulates amyloidogenic and nonamyloidogenic pathways in APPswe/PS1dE9 transgenic mice Journal article
Journal of Neuroscience Research, 2012,Volume: 90,Issue: 2,Page: 508-517
Authors:  Wang Y.;  Tang X.C.;  Zhang H.Y.
Favorite  |  View/Download:2/0  |  Submit date:2019/01/16
β-amyloid  Adam10  Alzheimer's disease  Bace1  Huperzine a  
Cryptotanshinone, a compound from Salvia miltiorrhiza modulates amyloid precursor protein metabolism and attenuates β-amyloid deposition through upregulating α-secretase in vivo and in vitro Journal article
Neuroscience Letters, 2009,Volume: 452,Issue: 2,Page: 90-95
Authors:  Mei Z.;  Zhang F.;  Tao L.;  Zheng W.;  Cao Y.;  Wang Z.;  Tang S.;  Le K.;  Chen S.;  Pi R.;  Liu P.
Favorite  |  View/Download:4/0  |  Submit date:2018/12/21
α-Secretase    Alzheimer's disease  Amyloid precursor protein (APP)  Cryptotanshinone