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Synthesis and biological evaluation of aza-crown ether–squaramide conjugates as anion/cation symporters Journal article
FUTURE MEDICINAL CHEMISTRY, 2019,Volume: 11,Issue: 10,Page: 1091-1106
Authors:  Xi-Hui Yu;  Xiong-Jie Cai;  Xiao-Qiao Hong;  Kin Yip Tam;  Kun Zhang;  Wen-Hua Chen
Favorite | View/Download：26/0 | TC[WOS]:5 TC[Scopus]:6 | Submit date：2020/05/21
Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2018,Volume: 26,Issue: 18,Page: 5053-5061
Authors:  Chen, Shao-Ru;  Li, Feng;  Ding, Mo-Yu;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Zhou, Guo-Chun;  Wang, Ying
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Andrographolide  Stat3 Inhibitor  Acute Liver Damage  Inflammation  
Identification and pharmaceutical evaluation of novel frog skin-derived serine proteinase inhibitor peptide PE-BBI (Pelophylax esculentus Bowman-Birk inhibitor) for the potential treatment of cancer Journal article
SCIENTIFIC REPORTS, 2018,Volume: 8
Authors:  Lyu, Peng;  Ge, Lilin;  Ma, Rui;  Wei, Ran;  McCrudden, Cian M.;  Chen, Tianbao;  Shaw, Chris;  Kwok, Hang Fai
Favorite | View/Download：37/0 | TC[WOS]:5 TC[Scopus]:6 | Submit date：2018/10/30
Periplaneta americana Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Rats by Keap1/Nrf-2 Activation, Intestinal Barrier Function, and Gut Microbiota Regulation Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:  Ma, Xuewei;  Hu, Yichen;  Li, Xin;  Zheng, Xiaoting;  Wang, Yitao;  Zhang, Jinming;  Fu, Chaomei;  Geng, Funeng
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Ulcerative Colitis  Periplaneta Americana  16s Rrna  Gut Microbiota  Intestinal Immunity  
Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 830,Page: 17-25
Authors:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping;  Wang, Yitao;  Li, Ao;  Lin, Li-Gen;  Lu, Jin-Jian
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Nagilactone e  Non-small Cell Lung Cancer  Cyclin B1  Cell Cycle  Apoptosis  
Anticancer drug discovery from Chinese medicinal herbs Journal article
CHINESE MEDICINE, 2018,Volume: 13
Authors:  Huang, Mu-Yang;  Zhang, Le-Le;  Ding, Jian;  Lu, Jin-Jian
Favorite | View/Download：133/0 | TC[WOS]:22 TC[Scopus]:24 | Submit date：2018/10/30
Chinese Medicinal Herbs  Anticancer  Drug Discovery  Natural Products  Formulae  
Targeting cancer metabolism to develop human lactate dehydrogenase (hLDH)5 inhibitors Journal article
DRUG DISCOVERY TODAY, 2018,Volume: 23,Issue: 7,Page: 1407-1415
Authors:  Zhang, Shao-Lin;  He, Yun;  Tam, Kin Yip
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Fast identification of anticancer constituents in Forsythiae Fructus based on metabolomics approaches Journal article
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2018,Volume: 154,Page: 312-320
Authors:  Bao, Jiaolin;  Ding, Ren-Bo;  Jia, Xuejing;  Liang, Yeer;  Liu, Fang;  Wang, Kai;  Zhang, Chao;  Li, Peng;  Wang, Yitao;  Wan, Jian-Bo;  He, Chengwei
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Forsythiae Fructus  Anticancer  Metabolomics  Multivariate Data Analysis  B16-f10 Melanoma  
Discovery and preliminary SAR of 14-aryloxy-andrographolide derivatives as antibacterial agents with immunosuppressant activity Journal article
RSC ADVANCES, 2018,Volume: 8,Issue: 17,Page: 9440-9456
Authors:  Li, Feng;  Li, Xiao-Min;  Sheng, Dekuan;  Chen, Shao-Ru;  Nie, Xin;  Liu, Zhuyun;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Wang, Ying;  Zhou, Guo-Chun
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Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B Journal article
NEUROPHARMACOLOGY, 2017,Volume: 126,Page: 12-24
Authors:  Guo, Baojian;  Hu, Shengquan;  Zheng, Chengyou;  Wang, Hongyu;  Luo, Fangcheng;  Li, Haitao;  Cui, Wei;  Yang, Xifei;  Cui, Guozhen;  Mak, Shinghung;  Choi, Tony Chung-Lit;  Ma, Edmond Dik-Lung;  Wang, Yuqiang;  Lee, Simon Ming Yuen;  Zhang, Zaijun;  Han, Yifan
View | Adobe PDF | Favorite | View/Download：536/13 | TC[WOS]:12 TC[Scopus]:13 | Submit date：2018/10/31
Parkinson's disease  SU4312  Neuroprotection  Myocyte enhancer factor 2D  Monoamine oxidase-B