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Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2018,Volume: 26,Issue: 18,Page: 5053-5061
作者:  Chen, Shao-Ru;  Li, Feng;  Ding, Mo-Yu;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Zhou, Guo-Chun;  Wang, Ying
浏览  |  Adobe PDF(2009Kb)  |  收藏  |  浏览/下载：425/53  |  提交时间：2018/10/30
Andrographolide  Stat3 Inhibitor  Acute Liver Damage  Inflammation  
Identification and pharmaceutical evaluation of novel frog skin-derived serine proteinase inhibitor peptide PE-BBI (Pelophylax esculentus Bowman-Birk inhibitor) for the potential treatment of cancer Journal article
SCIENTIFIC REPORTS, 2018,Volume: 8
作者:  Lyu, Peng;  Ge, Lilin;  Ma, Rui;  Wei, Ran;  McCrudden, Cian M.;  Chen, Tianbao;  Shaw, Chris;  Kwok, Hang Fai
收藏  |  浏览/下载：14/0  |  提交时间：2018/10/30
Periplaneta americana Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Rats by Keap1/Nrf-2 Activation, Intestinal Barrier Function, and Gut Microbiota Regulation Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
作者:  Ma, Xuewei;  Hu, Yichen;  Li, Xin;  Zheng, Xiaoting;  Wang, Yitao;  Zhang, Jinming;  Fu, Chaomei;  Geng, Funeng
浏览  |  Adobe PDF(4337Kb)  |  收藏  |  浏览/下载：363/15  |  提交时间：2018/10/30
Ulcerative Colitis  Periplaneta Americana  16s Rrna  Gut Microbiota  Intestinal Immunity  
Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 830,Page: 17-25
作者:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping;  Wang, Yitao;  Li, Ao;  Lin, Li-Gen;  Lu, Jin-Jian
浏览  |  Adobe PDF(3226Kb)  |  收藏  |  浏览/下载：184/23  |  提交时间：2018/10/30
Nagilactone e  Non-small Cell Lung Cancer  Cyclin B1  Cell Cycle  Apoptosis  
Anticancer drug discovery from Chinese medicinal herbs Journal article
CHINESE MEDICINE, 2018,Volume: 13
作者:  Huang, Mu-Yang;  Zhang, Le-Le;  Ding, Jian;  Lu, Jin-Jian
收藏  |  浏览/下载：63/0  |  提交时间：2018/10/30
Chinese Medicinal Herbs  Anticancer  Drug Discovery  Natural Products  Formulae  
Targeting cancer metabolism to develop human lactate dehydrogenase (hLDH)5 inhibitors Journal article
DRUG DISCOVERY TODAY, 2018,Volume: 23,Issue: 7,Page: 1407-1415
作者:  Zhang, Shao-Lin;  He, Yun;  Tam, Kin Yip
收藏  |  浏览/下载：9/0  |  提交时间：2018/10/30
Fast identification of anticancer constituents in Forsythiae Fructus based on metabolomics approaches Journal article
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2018,Volume: 154,Page: 312-320
作者:  Bao, Jiaolin;  Ding, Ren-Bo;  Jia, Xuejing;  Liang, Yeer;  Liu, Fang;  Wang, Kai;  Zhang, Chao;  Li, Peng;  Wang, Yitao;  Wan, Jian-Bo;  He, Chengwei
浏览  |  Adobe PDF(2154Kb)  |  收藏  |  浏览/下载：203/26  |  提交时间：2018/10/30
Forsythiae Fructus  Anticancer  Metabolomics  Multivariate Data Analysis  B16-f10 Melanoma  
Discovery and preliminary SAR of 14-aryloxy-andrographolide derivatives as antibacterial agents with immunosuppressant activity Journal article
RSC ADVANCES, 2018,Volume: 8,Issue: 17,Page: 9440-9456
作者:  Li, Feng;  Li, Xiao-Min;  Sheng, Dekuan;  Chen, Shao-Ru;  Nie, Xin;  Liu, Zhuyun;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Wang, Ying;  Zhou, Guo-Chun
浏览  |  Adobe PDF(583Kb)  |  收藏  |  浏览/下载：158/10  |  提交时间：2018/10/30
Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B Journal article
NEUROPHARMACOLOGY, 2017,Volume: 126,Page: 12-24
作者:  Guo, Baojian;  Hu, Shengquan;  Zheng, Chengyou;  Wang, Hongyu;  Luo, Fangcheng;  Li, Haitao;  Cui, Wei;  Yang, Xifei;  Cui, Guozhen;  Mak, Shinghung;  Choi, Tony Chung-Lit;  Ma, Edmond Dik-Lung;  Wang, Yuqiang;  Lee, Simon Ming Yuen;  Zhang, Zaijun;  Han, Yifan
浏览  |  Adobe PDF(2766Kb)  |  收藏  |  浏览/下载：141/5  |  提交时间：2018/10/31
Parkinson's disease  SU4312  Neuroprotection  Myocyte enhancer factor 2D  Monoamine oxidase-B  
Cleavable Multifunctional Targeting Mixed Micelles with Sequential pH-Triggered TAT Peptide Activation for Improved Antihepatocellular Carcinoma Efficacy Journal article
MOLECULAR PHARMACEUTICS, 2017,Volume: 14,Issue: 11,Page: 3644-3659
作者:  Zhang, Jinming;  Zheng, Yifeng;  Xie, Xi;  Wang, Lan;  Su, Ziren;  Wang, Yitao;  Leong, Kam W.;  Chen, Meiwan
浏览  |  Adobe PDF(2484Kb)  |  收藏  |  浏览/下载：347/46  |  提交时间：2018/10/30
Tumor-targeting  Glycyrrhetinic Acid  Ph-sensitive  Tat Exposure  Mixed Micelles