UM

Browse/Search Results:  1-10 of 138 Help

Selected(0)Clear Items/Page:    Sort:
Identification of Novel Pyruvate Dehydrogenase Kinase 1 (PDK1) Inhibitors by Kinase Activity-Based High-Throughput Screening for Anticancer Therapeutics Journal article
ACS Combinatorial Science, 2018,Volume: 20,Issue: 11,Page: 660-671
Authors:  Zhang W.;  Hu X.;  Chakravarty H.;  Yang Z.;  Tam K.Y.
Favorite  |  View/Download:6/0  |  Submit date:2018/12/18
cancer  high-throughput screening  pyruvate dehydrogenase kinase 1  small molecule inhibitors  Warburg effect  
Tetrahydrocurcumin, a major metabolite of curcumin, ameliorates allergic airway inflammation by attenuating Th2 response and suppressing the IL-4Rα-Jak1-STAT6 and Jagged1/Jagged2 -Notch1/Notch2 pathways in asthmatic mice Journal article
Clinical and Experimental Allergy, 2018,Volume: 48,Issue: 11,Page: 1494-1508
Authors:  Chen B.L.;  Chen Y.Q.;  Ma B.H.;  Yu S.F.;  Li L.Y.;  Zeng Q.X.;  Zhou Y.T.;  Wu Y.F.;  Liu W.L.;  Wan J.B.;  Yang Y.;  Li C.W.
Favorite  |  View/Download:2/0  |  Submit date:2018/12/28
airway inflammation  asthma  dietary factor  tetrahydrocurcumin  Th2 response  
Anticancer effects of some novel dichloroacetophenones through the inhibition of pyruvate dehydrogenase kinase 1 Journal article
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2018,Volume: 123,Page: 43-55
Authors:  Zhang, Shao-Lin;  Yang, Zheng;  Hu, Xiaohui;  Chakravarty, Harapriya;  Tam, Kin Yip
Favorite  |  View/Download:9/0  |  Submit date:2018/10/30
Dichloroacetophenone  Pyruvate Dehydrogenase Kinase  Pyruvate Dehydrogenase Complex  Anticancer Activity  Metabolic Reprogramming  
Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2018,Volume: 26,Issue: 18,Page: 5053-5061
Authors:  Chen, Shao-Ru;  Li, Feng;  Ding, Mo-Yu;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Zhou, Guo-Chun;  Wang, Ying
View  |  Adobe PDF(2009Kb)  |  Favorite  |  View/Download:301/41  |  Submit date:2018/10/30
Andrographolide  Stat3 Inhibitor  Acute Liver Damage  Inflammation  
Identification and pharmaceutical evaluation of novel frog skin-derived serine proteinase inhibitor peptide PE-BBI (Pelophylax esculentus Bowman-Birk inhibitor) for the potential treatment of cancer Journal article
SCIENTIFIC REPORTS, 2018,Volume: 8
Authors:  Lyu, Peng;  Ge, Lilin;  Ma, Rui;  Wei, Ran;  McCrudden, Cian M.;  Chen, Tianbao;  Shaw, Chris;  Kwok, Hang Fai
Favorite  |  View/Download:12/0  |  Submit date:2018/10/30
Synthetic Study toward the Total Synthesis of Taxezopidines A and B Journal article
ORGANIC LETTERS, 2018,Volume: 20,Issue: 18,Page: 5905-5909
Authors:  Hu, Ya-Jian;  Fan, Jian-Hong;  Li, Shaoping;  Zhao, Jing;  Li, Chuang-Chuang
View  |  Adobe PDF(1166Kb)  |  Favorite  |  View/Download:117/6  |  Submit date:2018/10/30
Liquid Chromatography-Tandem Mass Spectrometry Method Revealed that Lung Cancer Cells Exhibited Distinct Metabolite Profiles upon the Treatment with Different Pyruvate Dehydrogenase Kinase Inhibitors Journal article
JOURNAL OF PROTEOME RESEARCH, 2018,Volume: 17,Issue: 9,Page: 3012-3021
Authors:  Zhang, Wen;  Hu, Xiaohui;  Zhou, Wei;  Tam, Kin Yip
Favorite  |  View/Download:6/0  |  Submit date:2018/10/30
aerobic glycolysis  AZD7545  dichloroacetate  LC-MS/MS  pyruvate dehydrogenase kinases  cancer metabolism  
Anti-cancer effects of Rhizoma Curcumae against doxorubicin-resistant breast cancer cells Journal article
CHINESE MEDICINE, 2018,Volume: 13
Authors:  Zhong, Zhangfeng;  Yu, Haibing;  Wang, Shengpeng;  Wang, Yitao;  Cui, Liao
View  |  Adobe PDF(2911Kb)  |  Favorite  |  View/Download:138/12  |  Submit date:2018/10/30
Rhizoma Curcumae  Multidrug Resistance  Breast Cancer  Abc Transporters  Furanodiene  
Periplaneta americana Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Rats by Keap1/Nrf-2 Activation, Intestinal Barrier Function, and Gut Microbiota Regulation Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:  Ma, Xuewei;  Hu, Yichen;  Li, Xin;  Zheng, Xiaoting;  Wang, Yitao;  Zhang, Jinming;  Fu, Chaomei;  Geng, Funeng
View  |  Adobe PDF(4337Kb)  |  Favorite  |  View/Download:248/10  |  Submit date:2018/10/30
Ulcerative Colitis  Periplaneta Americana  16s Rrna  Gut Microbiota  Intestinal Immunity  
Biological activities of cationicity-enhanced and hydrophobicity-optimized analogues of an antimicrobial peptide, dermaseptin-PS3, from the skin secretion of phyllomedusa sauvagii Journal article
Toxins, 2018,Volume: 10,Issue: 8
Authors:  Tan Y.;  Chen X.;  Ma C.;  Xi X.;  Wang L.;  Zhou M.;  Burrows J.F.;  Kwok H.F.;  Chen T.
Favorite  |  View/Download:5/0  |  Submit date:2018/12/19
Anticancer Activity  Antimicrobial Activity  Antimicrobial Peptide (Amp)  Anuran Skin Secretion  Dermaseptin  Drug Design