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In Vitro and In Vivo Anti-Inflammatory Effects of Polyphyllin VII through Downregulating MAPK and NF-kappa B PathwaysDownregulating MAPK and NF-kappa B Pathways Journal article
MOLECULES, 2019,Volume: 24,Issue: 5
Authors:  Zhang, C;  Li, CY;  Jia, XJ;  Wang, K;  Tu, YB;  Wang, RC;  Liu, KC;  Lu, T;  He, CW
Favorite | View/Download:25/0 | TC[WOS]:8 TC[Scopus]:15 | Submit date:2020/01/09
Zebrafish  Polyphyllin Vii  Anti-inflammation  Macrophage  Mice  
Identification of Novel Pyruvate Dehydrogenase Kinase 1 (PDK1) Inhibitors by Kinase Activity-Based High-Throughput Screening for Anticancer Therapeutics Journal article
ACS Combinatorial Science, 2018,Volume: 20,Issue: 11,Page: 660-671
Authors:  Zhang W.;  Hu X.;  Chakravarty H.;  Yang Z.;  Tam K.Y.
Favorite | View/Download:20/0 | TC[WOS]:0 TC[Scopus]:2 | Submit date:2018/12/18
cancer  high-throughput screening  pyruvate dehydrogenase kinase 1  small molecule inhibitors  Warburg effect  
Toosendanin, a natural product, inhibited TGF-1-induced epithelial-mesenchymal transition through ERK/Snail pathway Journal article
PHYTOTHERAPY RESEARCH, 2018,Volume: 32,Issue: 10,Page: 2009-2020
Authors:  Luo, Weiwei;  Liu, Xin;  Sun, Wen;  Lu, Jin-Jian;  Wang, Yitao;  Chen, Xiuping
View | Adobe PDF | Favorite | View/Download:848/46 | TC[WOS]:4 TC[Scopus]:11 | Submit date:2018/10/30
Emt  Erk1/2  Snail  Lung Cancer  Toosendanin  
Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2018,Volume: 26,Issue: 18,Page: 5053-5061
Authors:  Chen, Shao-Ru;  Li, Feng;  Ding, Mo-Yu;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Zhou, Guo-Chun;  Wang, Ying
View | Adobe PDF | Favorite | View/Download:1442/102 | TC[WOS]:3 TC[Scopus]:5 | Submit date:2018/10/30
Andrographolide  Stat3 Inhibitor  Acute Liver Damage  Inflammation  
Synthetic Study toward the Total Synthesis of Taxezopidines A and B Journal article
ORGANIC LETTERS, 2018,Volume: 20,Issue: 18,Page: 5905-5909
Authors:  Hu, Ya-Jian;  Fan, Jian-Hong;  Li, Shaoping;  Zhao, Jing;  Li, Chuang-Chuang
View | Adobe PDF | Favorite | View/Download:554/30 | TC[WOS]:1 TC[Scopus]:2 | Submit date:2018/10/30
Gynosaponin TN-1 producing from the enzymatic conversion of gypenoside XLVI by naringinase and its cytotoxicity on hepatoma cell lines Journal article
Food and Chemical Toxicology, 2018,Volume: 119,Page: 161-168
Authors:  Zheng Y.;  Zheng Z.;  Ming Y.;  Lin M.;  Chen L.;  Huang W.;  Xiao J.;  Lin H.
Favorite | View/Download:28/0 | TC[WOS]:2 TC[Scopus]:2 | Submit date:2019/01/15
Biotransformation  Enzymatic Conversion  Gynosaponin Tn-1  Gypenoside Xlvi  Hepatoma Cell Lines  Naringinase  
Anti-cancer effects of Rhizoma Curcumae against doxorubicin-resistant breast cancer cells Journal article
CHINESE MEDICINE, 2018,Volume: 13
Authors:  Zhong, Zhangfeng;  Yu, Haibing;  Wang, Shengpeng;  Wang, Yitao;  Cui, Liao
View | Adobe PDF | Favorite | View/Download:562/21 | TC[WOS]:6 TC[Scopus]:9 | Submit date:2018/10/30
Rhizoma Curcumae  Multidrug Resistance  Breast Cancer  Abc Transporters  Furanodiene  
Periplaneta americana Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Rats by Keap1/Nrf-2 Activation, Intestinal Barrier Function, and Gut Microbiota Regulation Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:  Ma, Xuewei;  Hu, Yichen;  Li, Xin;  Zheng, Xiaoting;  Wang, Yitao;  Zhang, Jinming;  Fu, Chaomei;  Geng, Funeng
View | Adobe PDF | Favorite | View/Download:1288/23 | TC[WOS]:9 TC[Scopus]:19 | Submit date:2018/10/30
Ulcerative Colitis  Periplaneta Americana  16s Rrna  Gut Microbiota  Intestinal Immunity  
Biological activities of cationicity-enhanced and hydrophobicity-optimized analogues of an antimicrobial peptide, dermaseptin-PS3, from the skin secretion of phyllomedusa sauvagii Journal article
Toxins, 2018,Volume: 10,Issue: 8
Authors:  Tan Y.;  Chen X.;  Ma C.;  Xi X.;  Wang L.;  Zhou M.;  Burrows J.F.;  Kwok H.F.;  Chen T.
Favorite | View/Download:15/0 | TC[WOS]:4 TC[Scopus]:6 | Submit date:2018/12/19
Anticancer Activity  Antimicrobial Activity  Antimicrobial Peptide (Amp)  Anuran Skin Secretion  Dermaseptin  Drug Design  
Water soluble fraction from ethanolic extract of Clausena lansium seeds alleviates obesity and insulin resistance, and changes the composition of gut microbiota in high-fat diet-fed mice Journal article
JOURNAL OF FUNCTIONAL FOODS, 2018,Volume: 47,Page: 192-199
Authors:  Shen, Shengnan;  Liao, Qiwen;  Huang, Li;  Li, Dan;  Zhang, Qingwen;  Wang, Yitao;  Lee, Simon Ming-Yuen;  Lin, Ligen
View | Adobe PDF | Favorite | View/Download:770/43 | TC[WOS]:3 TC[Scopus]:5 | Submit date:2018/10/30
Clausena Lansium  Fat Mass Gain  Insulin Sensitivity  Gut Microbiota  Wampee