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Glutathione and H2O2 consumption promoted photodynamic and chemotherapy based on biodegradable MnO2–Pt@Au25 nanosheets Journal article
Chemical Engineering Journal, 2019,Volume: 356,Page: 543-553
Authors:  Bi H.;  Dai Y.;  Yang P.;  Xu J.;  Yang D.;  Gai S.;  He F.;  An G.;  Zhong C.;  Lin J.
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Au25 Clusters  Mno2 Nanosheets  Mri  Photodynamic Therapy  Pt(Iv) Prodrugs  
Self‐Assembled Metal‐Phenolic Nanoparticles for Enhanced Synergistic Combination Therapy against Colon Cancer Journal article
Advanced Biosystems, 2018,Issue: 1800241
Authors:  Ke Li;  Yunlu Dai;  Wen Chen;  Kang Yu;  Gao Xiao;  Joseph J. Richardson;  Wen Huang;  Junling Guo;  Xuepin Liao;  Bi Shi
Favorite  |  View/Download:4/0  |  Submit date:2019/01/28
Colon Cancer  Combination Therapy  Metal‐phenolic Networks  Rare Earth  Ros  
Identification of Novel Pyruvate Dehydrogenase Kinase 1 (PDK1) Inhibitors by Kinase Activity-Based High-Throughput Screening for Anticancer Therapeutics Journal article
ACS Combinatorial Science, 2018,Volume: 20,Issue: 11,Page: 660-671
Authors:  Zhang W.;  Hu X.;  Chakravarty H.;  Yang Z.;  Tam K.Y.
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cancer  high-throughput screening  pyruvate dehydrogenase kinase 1  small molecule inhibitors  Warburg effect  
Label-Free Quantification of Anticancer Drug Imatinib in Human Plasma with Surface Enhanced Raman Spectroscopy Journal article
ANALYTICAL CHEMISTRY, 2018,Volume: 90,Issue: 21,Page: 12670-12677
Authors:  Fornasaro, Stefano;  Bonifacio, Alois;  Marangon, Elena;  Buzzo, Mauro;  Toffoli, Giuseppe;  Rindzevicius, Tomas;  Schmidt, Michael Stenbaek;  Sergo, Valter
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Tetrahydrocurcumin, a major metabolite of curcumin, ameliorates allergic airway inflammation by attenuating Th2 response and suppressing the IL-4Rα-Jak1-STAT6 and Jagged1/Jagged2 -Notch1/Notch2 pathways in asthmatic mice Journal article
Clinical and Experimental Allergy, 2018,Volume: 48,Issue: 11,Page: 1494-1508
Authors:  Chen B.L.;  Chen Y.Q.;  Ma B.H.;  Yu S.F.;  Li L.Y.;  Zeng Q.X.;  Zhou Y.T.;  Wu Y.F.;  Liu W.L.;  Wan J.B.;  Yang Y.;  Li C.W.
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airway inflammation  asthma  dietary factor  tetrahydrocurcumin  Th2 response  
Tetrahydrocurcumin, a major metabolite of curcumin, ameliorates allergic airway inflammation by attenuating Th2 response and suppressing the IL-4R alpha-Jak1-STAT6 and Jagged1/Jagged2-Notch1/Notch2 pathways in asthmatic mice Journal article
CLINICAL AND EXPERIMENTAL ALLERGY, 2018,Volume: 48,Issue: 11,Page: 1494-1508
Authors:  Chen, Bin Lin;  Chen, Yan Qiu;  Ma, Bai Hui;  Yu, Si Fei;  Li, Li Yue;  Zeng, Qing Xiang;  Zhou, Yu Tao;  Wu, Yin Fan;  Liu, Wen Long;  Wan, Jian Bo;  Yang, Yan;  Li, Chun Wei
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airway inflammation  asthma  dietary factor  tetrahydrocurcumin  Th2 response  
Anticancer effects of some novel dichloroacetophenones through the inhibition of pyruvate dehydrogenase kinase 1 Journal article
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2018,Volume: 123,Page: 43-55
Authors:  Zhang, Shao-Lin;  Yang, Zheng;  Hu, Xiaohui;  Chakravarty, Harapriya;  Tam, Kin Yip
Favorite  |  View/Download:9/0  |  Submit date:2018/10/30
Dichloroacetophenone  Pyruvate Dehydrogenase Kinase  Pyruvate Dehydrogenase Complex  Anticancer Activity  Metabolic Reprogramming  
Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2018,Volume: 26,Issue: 18,Page: 5053-5061
Authors:  Chen, Shao-Ru;  Li, Feng;  Ding, Mo-Yu;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Zhou, Guo-Chun;  Wang, Ying
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Andrographolide  Stat3 Inhibitor  Acute Liver Damage  Inflammation  
Toosendanin, a natural product, inhibited TGF-1-induced epithelial-mesenchymal transition through ERK/Snail pathway Journal article
PHYTOTHERAPY RESEARCH, 2018,Volume: 32,Issue: 10,Page: 2009-2020
Authors:  Luo, Weiwei;  Liu, Xin;  Sun, Wen;  Lu, Jin-Jian;  Wang, Yitao;  Chen, Xiuping
View  |  Adobe PDF(2621Kb)  |  Favorite  |  View/Download:193/21  |  Submit date:2018/10/30
Emt  Erk1/2  Snail  Lung Cancer  Toosendanin  
Identification and pharmaceutical evaluation of novel frog skin-derived serine proteinase inhibitor peptide PE-BBI (Pelophylax esculentus Bowman-Birk inhibitor) for the potential treatment of cancer Journal article
SCIENTIFIC REPORTS, 2018,Volume: 8
Authors:  Lyu, Peng;  Ge, Lilin;  Ma, Rui;  Wei, Ran;  McCrudden, Cian M.;  Chen, Tianbao;  Shaw, Chris;  Kwok, Hang Fai
Favorite  |  View/Download:12/0  |  Submit date:2018/10/30