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Nano-carriers for delivery and targeting of active ingredients of Chinese medicine for hepatocellular carcinoma therapy Journal article
MATERIALS TODAY, 2019,Volume: 25,Page: 66-87
Authors:  Meiwan Chen;  Xingzhi Zhou;  Ruie Chen;  Junlin Wang;  Richard D. Ye;  Yitao Wang;  Chuanbin Wu;  Ram I. Mahato
Favorite | View/Download:16/0 | TC[WOS]:0 TC[Scopus]:4 | Submit date:2020/03/27
Astragalus Polysaccharide RAP Selectively Attenuates Paclitaxel-Induced Cytotoxicity Toward RAW 264.7 Cells by Reversing Cell Cycle Arrest and Apoptosis Journal article
FRONTIERS IN PHARMACOLOGY, 2019,Volume: 9
Authors:  Bao, WR;  Li, ZP;  Zhang, QW;  Li, LF;  Liu, HB;  Ma, DL;  Leung, CH;  Lu, AP;  Bian, Z;  Han, QB
Favorite | View/Download:16/0 | TC[WOS]:1 TC[Scopus]:3 | Submit date:2020/03/24
Cell Cycle  Astragalus Polysaccharide  Cytotoxicity  Protective Effect  Apoptosis  
Structure-Based Discovery of a Selective KDM5A Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines Journal article
CANCERS, 2019,Volume: 11,Issue: 1
Authors:  Yang, GJ;  Ko, CN;  Zhong, HJ;  Leung, CH;  Ma, DL
Favorite | View/Download:16/0 | TC[WOS]:7 TC[Scopus]:9 | Submit date:2020/03/24
Cell Cycle Arrest  Kdm5a  Jumonji Domain  Histone Demethylation  Protein-protein Interaction  Virtual Screening  Breast Cancer  Cell Senescence  
Dichloroacetophenones targeting at pyruvate dehydrogenase kinase 1 with improved selectivity and antiproliferative activity: Synthesis and structure-activity relationships Journal article
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018,Volume: 28,Issue: 21,Page: 3441-3445
Authors:  Zhang, Shao-Lin;  Yang, Zheng;  Hu, Xiaohui;  Tam, Kin Yip
Favorite | View/Download:23/0 | TC[WOS]:2 TC[Scopus]:2 | Submit date:2018/10/30
Pyruvate dehydrogenase kinase  Pyruvate dehydrogenase complex  Antiproliferative activity  Dichloroacetophenone  Kinase inhibition  
Differential angiogenic activities of naringin and naringenin in zebrafish in vivo and human umbilical vein endothelial cells in vitro Journal article
Journal of Functional Foods, 2018,Volume: 49,Page: 369-377
Authors:  Linmin Chen;  Binrui Yang;  Benqin Tang;  Guiyi Gong;  Hiotong Kam;  Cheng Gao;  Yan Chen;  Ruibing Wang;  Simon Ming Yuen Lee
Favorite | View/Download:24/0 | TC[WOS]:2 TC[Scopus]:2 | Submit date:2018/11/06
Angiogenesis  Huvec  Naringin  Zebrafish  
Toosendanin, a natural product, inhibited TGF-1-induced epithelial-mesenchymal transition through ERK/Snail pathway Journal article
PHYTOTHERAPY RESEARCH, 2018,Volume: 32,Issue: 10,Page: 2009-2020
Authors:  Luo, Weiwei;  Liu, Xin;  Sun, Wen;  Lu, Jin-Jian;  Wang, Yitao;  Chen, Xiuping
View | Adobe PDF | Favorite | View/Download:848/46 | TC[WOS]:4 TC[Scopus]:11 | Submit date:2018/10/30
Emt  Erk1/2  Snail  Lung Cancer  Toosendanin  
Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2018,Volume: 26,Issue: 18,Page: 5053-5061
Authors:  Chen, Shao-Ru;  Li, Feng;  Ding, Mo-Yu;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Zhou, Guo-Chun;  Wang, Ying
View | Adobe PDF | Favorite | View/Download:1442/102 | TC[WOS]:3 TC[Scopus]:5 | Submit date:2018/10/30
Andrographolide  Stat3 Inhibitor  Acute Liver Damage  Inflammation  
Tanshinone IIA attenuates insulin like growth factor 1-induced cell proliferation in PC12 cells through the PI3K/Akt and MEK/ERK pathways Journal article
International Journal of Molecular Sciences, 2018,Volume: 19,Issue: 9
Authors:  Wang H.;  Su X.;  Fang J.;  Xin X.;  Zhao X.;  Gaur U.;  Wen Q.;  Xu J.;  Little P.J.;  Zheng W.
Favorite | View/Download:24/0 | TC[WOS]:7 TC[Scopus]:12 | Submit date:2018/12/21
Akt  Antiproliferation  ERK  IGF-1R  Tanshinone IIA  
Ponatinib exerts anti-angiogenic effects in the zebrafish and human umbilical vein endothelial cells via blocking VEGFR signaling pathway Journal article
Oncotarget, 2018,Volume: 9,Issue: 62,Page: 31958-31970
Authors:  Nana Ai;  Cheong-Meng Chong.;  Weiting Chen;  Zhe Hu;  Huanxing Su;  Guokai Chen;  Queenie Wing Lei Wong;  Wei Ge
Favorite | View/Download:24/0 | TC[WOS]:0 TC[Scopus]:6 | Submit date:2018/12/11
Angiogenesis  Enos  Huvec  Mapk  Ponatinib  
A novel Ca2+ current blocker promotes angiogenesis and cardiac healing after experimental myocardial infarction in mice Journal article
PHARMACOLOGICAL RESEARCH, 2018,Volume: 134,Page: 109-117
Authors:  Cui, Guozhen;  Xin, Qiqi;  Tseng, Hisa Hui Ling;  Hoi, Maggie PuiMan;  Wang, Yan;  Yang, Binrui;  Choi, InLeng;  Wang, Yuqiang;  Yuan, Rong;  Chen, Keji;  Cong, Weihong;  Lee, Simon MingYuen
View | Adobe PDF | Favorite | View/Download:539/17 | TC[WOS]:4 TC[Scopus]:5 | Submit date:2018/10/30
Cardioprotection  Angiogenesis  ADTM  Zebrafish  VEGF