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Shikonin promotes ubiquitination and degradation of cIAP1/2-mediated apoptosis and necrosis in triple negative breast cancer cells Journal article
Chinese Medicine (United Kingdom), 2021,Volume: 16,Issue: 1
Authors:  Wang,Anqi;  Liu,Jiayu;  Yang,Yuhan;  Chen,Zhejie;  Gao,Caifang;  Wang,Zhanguo;  Fu,Chaomei;  Zou,Liang;  Wang,Shengpeng
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Apoptosis  Breast cancer  Necrosis  Shikonin  Ubiquitination  
The pharmacological activity of epigallocatechin-3-gallate (EGCG) on Alzheimer's disease animal model: A systematic review Journal article
Phytomedicine, 2020,Volume: 79
Authors:  Zhang,Shuang;  Zhu,Qi;  Chen,Jia Yue;  OuYang,Defang;  Lu,Jia Hong
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AD animal models  Alzheimer's disease  Clinical trials  EGCG  Neuroprotective effects  Systematic review  
Burst release of encapsulated annexin A5 in tumours boosts cytotoxic T-cell responses by blocking the phagocytosis of apoptotic cells Journal article
Nature Biomedical Engineering, 2020,Volume: 4,Issue: 11,Page: 1102-1116
Authors:  Li,Ling;  Zou,Jianhua;  Dai,Yunlu;  Fan,Wenpei;  Niu,Gang;  Yang,Zhen;  Chen,Xiaoyuan
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Induction of programmed necrosis: A novel anti-cancer strategy for natural compounds Journal article
Pharmacology and Therapeutics, 2020,Volume: 214
Authors:  Yu,Jie;  Zhong,Bingling;  Xiao,Qingwen;  Du,Lida;  Hou,Ying;  Sun,Hong Shuo;  Lu,Jin Jian;  Chen,Xiuping
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Cancer  Natural compounds  Programmed necrosis  
Pristimerin-induced uveal melanoma cell death via inhibiting PI3K/Akt/FoxO3a signalling pathway Journal article
Journal of Cellular and Molecular Medicine, 2020,Volume: 24,Issue: 11,Page: 6208-6219
Authors:  Yan,Fengxia;  Liao,Rifang;  Silva,Marta;  Li,Shuai;  Jiang,Yizhou;  Peng,Tangming;  Lazarovici,Philip;  Zheng,Wenhua
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cell death  FoxO3a  nuclear accumulation  Pristimerin  uveal melanoma  
Putting the Brakes on Tumorigenesis with Natural Products of Plant Origin: Insights into the Molecular Mechanisms of Actions and Immune Targets for Bladder Cancer Treatment Journal article
Cells, 2020,Volume: 9,Issue: 5
Authors:  Wu,Qiushuang;  Wong,Janet P.C.;  Kwok,Hang Fai
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apoptosis  bladder cancer  immunomolecular targets  natural products  plants  
Activation of notch 3/c-MYC/CHOP axis regulates apoptosis and promotes sensitivity of lung cancer cells to mTOR inhibitor everolimus Journal article
Biochemical Pharmacology, 2020,Volume: 175
Authors:  Li,Ting;  Xu,Xiao Huang;  Guo,Xia;  Yuan,Tao;  Tang,Zheng Hai;  Jiang,Xiao Ming;  Xu,Yu Lian;  Zhang,Le Le;  Chen,Xiuping;  Zhu,Hong;  Shi,Jia Jie;  Lu,Jin Jian
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Apoptosis  c-MYC  CHOP  Lung cancer  Notch 3  
In Vitro and MD Simulation Study to Explore Physicochemical Parameters for Antibacterial Peptide to Become Potent Anticancer Peptide Journal article
Molecular Therapy - Oncolytics, 2020,Volume: 16,Page: 7-19
Authors:  Ma,Rui;  Wong,Sin Wa;  Ge,Lilin;  Shaw,Chris;  Siu,Shirley W.I.;  Kwok,Hang Fai
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angiogenesis  anticancer peptides  antimicrobial peptides  apoptosis  drug discovery and development  molecular dynamics  targeted therapy  
Ethanol extract of Ophiorrhiza pumila suppresses liver cancer cell proliferation and migration Journal article
Chinese Medicine (United Kingdom), 2020,Volume: 15,Issue: 1
Authors:  Liu,Hui;  Liao,Wanqin;  Fan,Lixia;  Zheng,Zhaoguang;  Liu,Dahai;  Zhang,Qing Wen;  Yang,Anping;  Liu,Fang
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Apoptosis  Liver cancer  Migration  Ophiorrhiza pumila  Proliferation  
13-Methylberberine improves endothelial dysfunction by inhibiting NLRP3 inflammasome activation via autophagy induction in human umbilical vein endothelial cells Journal article
Chinese Medicine (United Kingdom), 2020,Volume: 15,Issue: 1
Authors:  Peng,Zhihua;  Zhan,Hong;  Shao,Yijia;  Xiong,Yan;  Zeng,Lijin;  Zhang,Cong;  Liu,Zhihao;  Huang,Zhenhua;  Su,Huanxing;  Yang,Zhen
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13-Methylberberine  Anti-inflammatory  Atherosclerosis  Autophagy inducer  NLRP3 inflammasome