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Serum amyloid A promotes LPS clearance and suppresses LPS-induced inflammation and tissue injury Journal article
EMBO REPORTS, 2018,Volume: 19,Issue: 10
Authors:  Cheng, Ni;  Liang, Yurong;  Du, Xiaoping;  Ye, Richard D.
View  |  Adobe PDF(2278Kb)  |  Favorite  |  View/Download:138/3  |  Submit date:2018/10/30
acute-phase response  inflammation  innate immunity  lipopolysaccharide  serum amyloid A  
Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B Journal article
NEUROPHARMACOLOGY, 2017,Volume: 126,Page: 12-24
Authors:  Guo, Baojian;  Hu, Shengquan;  Zheng, Chengyou;  Wang, Hongyu;  Luo, Fangcheng;  Li, Haitao;  Cui, Wei;  Yang, Xifei;  Cui, Guozhen;  Mak, Shinghung;  Choi, Tony Chung-Lit;  Ma, Edmond Dik-Lung;  Wang, Yuqiang;  Lee, Simon Ming Yuen;  Zhang, Zaijun;  Han, Yifan
View  |  Adobe PDF(2766Kb)  |  Favorite  |  View/Download:109/4  |  Submit date:2018/10/31
Parkinson's disease  SU4312  Neuroprotection  Myocyte enhancer factor 2D  Monoamine oxidase-B  
Phosphoproteome-based kinase activity profiling reveals the critical role of MAP2K2 and PLK1 in neuronal autophagy Journal article
AUTOPHAGY, 2017,Volume: 13,Issue: 11,Page: 1969-1980
Authors:  Chen, Lei-Lei;  Wang, Yong-Bo;  Song, Ju-Xian;  Deng, Wan-Kun;  Lu, Jia-Hong;  Ma, Li-Li;  Yang, Chuan-Bin;  Li, Min;  Xue, Yu
Favorite  |  View/Download:11/0  |  Submit date:2018/10/30
autophagy  corynoxine  kinase activity  phosphoproteome  phosphorylation  protein kinase  
Pathway-based analysis of genome-wide siRNA screens reveals the regulatory landscape of app processing Journal article
PLoS ONE, 2015,Volume: 10,Issue: 2
Authors:  Camargo L.M.;  Zhang X.D.;  Loerch P.;  Caceres R.M.;  Marine S.D.;  Uva P.;  Ferrer M.;  De Rinaldis E.;  Stone D.J.;  Majercak J.;  Ray W.J.;  Chen Y.-A.;  Shearman M.S.;  Mizuguchi K.
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Serum amyloid A1 isoforms display different efficacy at Toll-like receptor 2 and formyl peptide receptor 2 Journal article
Immunobiology, 2014,Volume: 219,Issue: 12,Page: 916-923
Authors:  Chen M.;  Zhou H.;  Cheng N.;  Qian F.;  Ye R.D.
Favorite  |  View/Download:5/0  |  Submit date:2018/11/07
Formyl peptide receptors  Inflammation  Innate immunity  Polymorphism  Serum amyloid A  Toll-like receptors  
Existence of different types of senile plaques between brain and spinal cord of TgCRND8 mice Journal article
Neurochemistry International, 2013,Volume: 62,Issue: 3,Page: 211-220
Authors:  Yuan Q.;  Su H.;  Zhang Y.;  Chau W.H.;  Ng C.T.;  Wu W.;  Lin Z.-X.
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Alzheimer's disease  Senile plaques  Spinal cord and glial reaction  TgCRND8 mice  
Berberine ameliorates β-amyloid pathology, gliosis, and cognitive impairment in an Alzheimer's disease transgenic mouse model Journal article
Neurobiology of Aging, 2012,Volume: 33,Issue: 12,Page: 2903-2919
Authors:  Durairajan S.S.K.;  Liu L.-F.;  Lu J.-H.;  Chen L.-L.;  Yuan Q.;  Chung S.K.;  Huang L.;  Li X.-S.;  Huang J.-D.;  Li M.
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β-amyloid  Alzheimer's disease  Amyloid precursor protein  Berberine  Glycogen synthase kinase  Tau phosphorylation  TgCRND8 mice  
In vitro screening on amyloid precursor protein modulation of plants used in Ayurvedic and Traditional Chinese medicine for memory improvement Journal article
Journal of Ethnopharmacology, 2012,Volume: 141,Issue: 2,Page: 754-760
Authors:  Liu L.-F.;  Durairajan S.S.K.;  Lu J.-H.;  Koo I.;  Li M.
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  Alzheimer's disease  Amyloid precursor protein  Ayurvedic medicine  Traditional Chinese medicine  
Berberine Alkaloid as a Medicament for Prophylaxis and Treatment of Alzheimer’s Disease Patent
专利类型: 发明专利, 专利号: US20130237556A1,
Authors:  Min LI;  Siva Sundara Kumar DURAIRAJAN;  Liangfeng LIU;  Jiahong LU,
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Huperzine a alleviates synaptic deficits and modulates amyloidogenic and nonamyloidogenic pathways in APPswe/PS1dE9 transgenic mice Journal article
Journal of Neuroscience Research, 2012,Volume: 90,Issue: 2,Page: 508-517
Authors:  Wang Y.;  Tang X.C.;  Zhang H.Y.
Favorite  |  View/Download:1/0  |  Submit date:2019/01/16
β-amyloid  Adam10  Alzheimer's disease  Bace1  Huperzine a