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Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 9,Page: 1193-1204
Authors:  Ting-ting Zhou;  Tong Zhao;  Fei Ma;  Yi-nan Zhang;  Jing Jiang;  Yuan Ruan;  Qiu-ying Yan;  Gai-hong Wang;  Jin Ren;  Xiao-wei Guan;  Jun Guo;  Yong-hua Zhao;  Ji-ming Ye;  Li-hong Hu;  Jing Chen;  Xu Shen
Favorite  |  View/Download:5/0  |  Submit date:2020/04/14
Type 2 Diabetes Mellitus  Hepatic Gluconeogenesis  Ampk Signaling Pathway  (e)-3-(2-(Quinoline-4-yl)Vinyl)-1h-indol-6-ol (Qvo)  4-[2-(1h-indol-3-yl)Vinyl]Quinoline (Ivq)  Prodrug  
Metformin protects PC12 cells and hippocampal neurons from H2O (2)-induced oxidative damage through activation of AMPK pathway Journal article
JOURNAL OF CELLULAR PHYSIOLOGY, 2019,Volume: 234,Issue: 9,Page: 16619-16629
Authors:  Xia Zhao;  Zhiwen Zeng;  Uma Gaur;  Jiankang Fang;  Tangming Peng;  Shuai Li;  Wenhua Zheng
Favorite  |  View/Download:5/0  |  Submit date:2020/06/11
Aging  Amp-activated Protein Kinase  Hydrogen Peroxide  Metformin  Pc12 Cells  
Elevated Exogenous Pyruvate Potentiates Mesodermal Differentiation through Metabolic Modulation and AMPK/mTOR Pathway in Human Embryonic Stem Cells Journal article
STEM CELL REPORTS, 2019,Volume: 13,Issue: 2,Page: 338-351
Authors:  Chengcheng Song;  Faxiang Xu;  Zhili Ren;  Yumeng Zhang;  Ya Meng;  Yiqi Yang;  Shreyas Lingadahalli;  Edwin Cheung;  Gang Li;  Weiwei Liu;  Jianbo Wan;  Yang Zhao;  Guokai Chen
Favorite  |  View/Download:12/0  |  Submit date:2020/04/22
Hescs  Pyruvate  Bmp4  Glycolysis  Tca Cycle  Ampk  Wnt  Metabolism  Mesoderm  Differentiation  
Phosphorylation of TET2 by AMPK is indispensable in myogenic differentiation Journal article
EPIGENETICS & CHROMATIN, 2019,Volume: 12
Authors:  Ting Zhang;  Xiaowen Guan;  Un Lam Choi;  Qiang Dong;  Melody M. T. Lam;  Jianming Zeng;  Jun Xiong;  Xianju Wang;  Terence C. W. Poon;  Hongjie Zhang;  Xuanjun Zhang;  Hailin Wang;  Ruiyu Xie;  Bing Zhu;  Gang Li
Favorite  |  View/Download:8/0  |  Submit date:2020/05/26
Ampk  Tet2  Phosphorylation  Myogenesis  Pax7  
A combination of Pueraria lobata and Silybum marianum protects against alcoholic liver disease in mice Journal article
PHYTOMEDICINE, 2019,Volume: 58
Authors:  Feng Ruibing;  Chen Jie-Hua;  Liu Cong-Hui;  Xia Fang-Bo;  Xiao Zeyu;  hang Xuguang;  Wan Jian-Bo
Favorite  |  View/Download:9/0  |  Submit date:2020/04/22
SiL.bum Marianum(L.)Gaerth  Pueraria Lobata(Wild.)Ohwi  Alcoholic Liver Disease  Hepatic Inflammation  Intestinal Barrier Dysfunction  
Upregulation of phosphoserine phosphatase contributes to tumor progression and predicts poor prognosis in non-small cell lung cancer patients Journal article
THORACIC CANCER, 2019,Volume: 10,Issue: 5,Page: 1203-1212
Authors:  Li Liao;  Huajian Yu;  Mengxi Ge;  Qiong Zhan;  Ruofan Huang;  Xiaoyu Ji;  Xiaohua Liang;  Xinli Zhou
Favorite  |  View/Download:7/0  |  Submit date:2020/03/10
Akt/ampk Signaling Pathway  Metastasis  Nsclc  Proliferation  Psph  
Myricanol mitigates lipid accumulation in 3T3-L1 adipocytes and high fat diet-fed zebrafish via activating AMP-activated protein kinase Journal article
Food Chemistry, 2019,Volume: 270,Page: 305-314
Authors:  Shen S.;  Liao Q.;  Feng Y.;  Liu J.;  Pan R.;  Lee S.M.-Y.;  Lin L.
Favorite  |  View/Download:17/0  |  Submit date:2018/11/06
Adipogenesis  Amp-activated Protein Kinase  Insulin Sensitivity  Lipid Accumulation  Myricanol  Zebrafish  
Deciphering the metabolic role of AMPK in cancer multi-drug resistance Journal article
SEMINARS IN CANCER BIOLOGY, 2018,Volume: 56,Page: 56-71
Authors:  Wen Tan;  Zhangfeng Zhong;  Randy P. Carney;  Yongfan Men;  Jiannan Li;  Tingrui Pan;  Yitao Wang
Favorite  |  View/Download:4/0  |  Submit date:2020/03/27
Ampk  Metabolic Reprogramming  Multi-drug Resistance  Cancer  
Anti-cancer effects of Rhizoma Curcumae against doxorubicin-resistant breast cancer cells Journal article
CHINESE MEDICINE, 2018,Volume: 13
Authors:  Zhong, Zhangfeng;  Yu, Haibing;  Wang, Shengpeng;  Wang, Yitao;  Cui, Liao
View  |  Adobe PDF(2911Kb)  |  Favorite  |  View/Download:314/16  |  Submit date:2018/10/30
Rhizoma Curcumae  Multidrug Resistance  Breast Cancer  Abc Transporters  Furanodiene  
Berberine protects human retinal pigment epithelial cells from hydrogen peroxide-induced oxidative damage through activation of AMPK Journal article
International Journal of Molecular Sciences, 2018,Volume: 19,Issue: 6
Authors:  Li S.;  Gaur U.;  Chong C.-M.;  Lin S.;  Fang J.;  Zeng Z.;  Wang H.;  Zheng W.
Favorite  |  View/Download:7/0  |  Submit date:2018/12/21
Age-related macular degeneration  AMPK  Berberine  D407 cells