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Brij-grafted-chitosan copolymers with function of P-glycoprotein modulation: Synthesis, characterization and in vitro investigations Journal article
Carbohydrate Polymers, 2019,Volume: 204,Page: 89-96
Authors:  Wei Xiong;  Guan Ding Zhao;  Xunqing Yin;  Ke Gang Linghu;  John M.T. Chu;  Gordon T.C. Wong;  Haifeng Li;  Hua Yu;  Yi Tao Wang
Favorite  |  View/Download:110/0  |  Submit date:2018/11/15
Chitosan  Brij-s20  Solubility  P-glycoprotein  Drug Efflux  
Highly efficient ratiometric extracellular oxygen sensors through physical incorporation of a conjugated polymer and PtTFPP in graft copolymers Journal article
SENSORS AND ACTUATORS B-CHEMICAL, 2018,Volume: 273,Page: 242-252
Authors:  Zhao, Qian;  Pan, Tingting;  Xiang, Gang;  Mei, Zhipeng;  Jiang, Jiapei;  Li, Gang;  Zou, Xianshao;  Chen, Meiwan;  Sun, Dazhi;  Jiang, Shimei;  Tian, Yanqing
Favorite  |  View/Download:18/0  |  Submit date:2018/10/30
Amphiphilic graft copolymer  Conjugated polymer  Oxygen sensor  FRET  Micelles  Oxygen consumption  
Preparation and anti-tumor activity study of long-circulating, self-assembled gambogic acid nanoparticles 藤黄酸长循环纳米粒的制备及其抗肿瘤作用研究 Journal article
Chinese Journal of New Drugs, 2018,Volume: 27,Issue: 14,Page: 1639-1644
Authors:  Guo M.-R.;  Wang F.;  Chen L.-J.;  Ouyang D.-F.;  Liu Y.;  Liang X.;  Zhang G.-L.;  Zhang J.-F.;  Liu H.-S.
Favorite  |  View/Download:6/0  |  Submit date:2019/01/15
Anti-tumor  Gambogic acid  Nanoparticles  PCL-PEG-PCL  
Redox-sensitive micelles composed of disulfide-linked Pluronic-linoleic acid for enhanced anticancer efficiency of brusatol Journal article
INTERNATIONAL JOURNAL OF NANOMEDICINE, 2018,Volume: 13,Page: 939-956
Authors:  Zhane, Jinming;  Fang, Xiaobin;  Li, Zeyong;  Chan, Hon Fai;  Lin, Zhixiu;  Wang, Yitao;  Chen, Meiwan
View  |  Adobe PDF(704Kb)  |  Favorite  |  View/Download:270/7  |  Submit date:2018/10/30
Poloxamer188  Tumor Micro-environment  Glutathione  Brucea Javanica  Cancer Treatment  
Cleavable Multifunctional Targeting Mixed Micelles with Sequential pH-Triggered TAT Peptide Activation for Improved Antihepatocellular Carcinoma Efficacy Journal article
MOLECULAR PHARMACEUTICS, 2017,Volume: 14,Issue: 11,Page: 3644-3659
Authors:  Zhang, Jinming;  Zheng, Yifeng;  Xie, Xi;  Wang, Lan;  Su, Ziren;  Wang, Yitao;  Leong, Kam W.;  Chen, Meiwan
View  |  Adobe PDF(2484Kb)  |  Favorite  |  View/Download:572/48  |  Submit date:2018/10/30
Tumor-targeting  Glycyrrhetinic Acid  Ph-sensitive  Tat Exposure  Mixed Micelles  
Drug-loaded pH-responsive polymeric micelles: Simulations and experiments of micelle formation, drug loading and drug release Journal article
COLLOIDS AND SURFACES B-BIOINTERFACES, 2017,Volume: 158,Page: 709-716
Authors:  Li, Qiu;  Yao, Weishang;  Yu, Xiang;  Zhang, Baolei;  Dong, Junxing;  Jin, Yiguang
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Block copolymer  Computer simulation  pH-responsive  Polymeric micelles  Paclitaxel  Molecular dynamics  Coarse grain  Dissipative particle dynamics  
Poly(epsilon-caprolactone)-containing graft copolymers for ratiometric extracellular oxygen sensing Journal article
SENSORS AND ACTUATORS B-CHEMICAL, 2017,Volume: 248,Page: 108-118
Authors:  Zou, Xianshao;  Pan, Tingting;  Jiang, Jiapei;  Li, Gang;  Song, Cheng;  Sun, Ruofan;  Yang, Ziyun;  Sun, Dazhi;  Hou, Chunhui;  Chen, Meiwan;  Tian, Yanqing
Favorite  |  View/Download:16/0  |  Submit date:2018/10/30
Oxygen sensor  Ratiometric sensor  Graft copolymer  Oxygen consumption  Micelles  
Reversal of paclitaxel resistance in human ovarian cancer cells with redox-responsive micelles consisting of alpha-tocopheryl succinate-based polyphosphoester copolymers Journal article
ACTA PHARMACOLOGICA SINICA, 2017,Volume: 38,Issue: 6,Page: 859-873
Authors:  Chen, Feng-qian;  Zhang, Jin-ming;  Fang, Xie-fan;  Yu, Hua;  Liu, Yu-ling;  Li, Hui;  Wang, Yi-tao;  Chen, Mei-wan
Favorite  |  View/Download:10/0  |  Submit date:2018/10/30
Ovarian Carcinoma  Paclitaxel  Multidrug Resistance  Nanomedicines  D-alpha-tocopheryl Succinate  Redox-responsive Micelles  P-gp  Apoptosis  Cell Cycle Arrest  A2780/ptx Cells  
Co-delivery of paclitaxel and tetrandrine via iRGD peptide conjugated lipid-polymer hybrid nanoparticles overcome multidrug resistance in cancer cells Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Zhang, Jinming;  Wang, Lu;  Chan, Hon Fai;  Xie, Wei;  Chen, Sheng;  He, Chengwei;  Wang, Yitao;  Chen, Meiwan
View  |  Adobe PDF(1919Kb)  |  Favorite  |  View/Download:301/9  |  Submit date:2018/10/30
Triphenylphosphonium-modified poly(ethylene glycol)-poly(ε-caprolactone) micelles for mitochondria- targeted gambogic acid delivery Journal article
International Journal of Pharmaceutics, 2017,Volume: 522,Issue: 1-2,Page: 21-33
Authors:  Xu Y.;  Wang S.;  Chan H.F.;  Liu Y.;  Li H.;  He C.;  Li Z.;  Chen M.
Favorite  |  View/Download:7/0  |  Submit date:2018/12/27
Gambogic acid  Lung cancer  Mitochondrial targeting  Polymeric micelles