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Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 10,Page: 1279-1291
Authors:  Lei Fan;  Xiao-xia Qiu;  Zhi-yuan Zhu;  Jian-lu Lv;  Jian Lu;  Fei Mao;  Jin Zhu;  Jia-ying Wang;  Xiao-wei Guan;  Jing Chen;  Jin Ren;  Ji-ming Ye;  Yong-hua Zhao;  Jian Li;  Xu Shen
Favorite  |  View/Download:11/0  |  Submit date:2020/04/14
App/ps1 Transgenic Mice  Alzheimer’s Disease  Autophagy  Inflammation  Nitazoxanide  
Activatable Small-Molecule Photoacoustic Probes that Cross the Blood-Brain Barrier for Visualization of Copper(II) in Mice with Alzheimer's Disease Journal article
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2019,Volume: 58,Issue: 36,Page: 12415-12419
Authors:  Shichao Wang;  Zonghai Sheng;  Zhenguo Yang;  Dehong Hu;  Xiaojing Long;  Gang Feng;  Yubin Liu;  Zhen Yuan;  Jingjing Zhang;  Hairong Zheng;  Xuanjun Zhang
Favorite  |  View/Download:1/0  |  Submit date:2020/05/26
Alzheimer's Disease  Biosensors  Blood-brain Barrier  Copper  Photoacoustic Probe  
Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2018,Volume: 26,Issue: 18,Page: 5053-5061
Authors:  Chen, Shao-Ru;  Li, Feng;  Ding, Mo-Yu;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Zhou, Guo-Chun;  Wang, Ying
View  |  Adobe PDF(2009Kb)  |  Favorite  |  View/Download:728/60  |  Submit date:2018/10/30
Andrographolide  Stat3 Inhibitor  Acute Liver Damage  Inflammation  
MK2 mediates macrophage activation and acute lung injury by regulating let-7e miRNA Journal article
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2018,Volume: 315,Issue: 3,Page: L371-L381
Authors:  Wu, Yaxian;  He, Huiqiong;  Ding, Yunhe;  Liu, Sirui;  Zhang, Depeng;  Wang, Jun;  Jiang, Hongchao;  Zhang, Dan;  Sun, Lei;  Ye, Richard D.;  Qian, Feng
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acute lung injury  let-7e  lipopolysaccharides  macrophage  MAPK-activated protein kinase 2  miRNA  MK2  
A rare variant in MLKL confers susceptibility to ApoE ɛ4-negative Alzheimer's disease in Hong Kong Chinese population Journal article
Neurobiology of Aging, 2018,Volume: 68,Page: 160.e1-160.e7
Authors:  Wang B.;  Bao S.;  Zhang Z.;  Zhou X.;  Wang J.;  Fan Y.;  Zhang Y.;  Li Y.;  Chen L.;  Jia Y.;  Li J.;  Li M.;  Zheng W.;  Mu N.;  Wang L.;  Yu Z.;  Wong D.S.M.;  Zhang Y.;  Kwan J.;  Ka-Fung Mak H.;  Ambalavanan A.;  Zhou S.;  Cai W.;  Zheng J.;  Huang S.;  Rouleau G.A.;  Yang W.;  Rogaeva E.;  Ma X.;  St George-Hyslop P.;  Chu L.W.;  Song Y.-Q.
Favorite  |  View/Download:6/0  |  Submit date:2018/12/21
Apoe Ɛ4-negative  Late-onset Alzheimer's Disease  Mlkl  Whole Exome Sequencing  
A novel Ca2+ current blocker promotes angiogenesis and cardiac healing after experimental myocardial infarction in mice Journal article
PHARMACOLOGICAL RESEARCH, 2018,Volume: 134,Page: 109-117
Authors:  Cui, Guozhen;  Xin, Qiqi;  Tseng, Hisa Hui Ling;  Hoi, Maggie PuiMan;  Wang, Yan;  Yang, Binrui;  Choi, InLeng;  Wang, Yuqiang;  Yuan, Rong;  Chen, Keji;  Cong, Weihong;  Lee, Simon MingYuen
View  |  Adobe PDF(3018Kb)  |  Favorite  |  View/Download:281/11  |  Submit date:2018/10/30
Cardioprotection  Angiogenesis  ADTM  Zebrafish  VEGF  
UPLC/Q-TOFMS-Based Metabolomics Approach to Reveal the Protective Role of Other Herbs in An-Gong-Niu-Huang Wan Against the Hepatorenal Toxicity of Cinnabar and Realgar Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:  Xia, Fangbo;  Li, Ao;  Chai, Yushuang;  Xiao, Xiao;  Wan, Jianbo;  Li, Peng;  Wang, Yitao
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An-gong-niu-huang Wan  Cinnabar  Realgar  Metabonomics  Detoxification  Inflammation  
Pinocembrin from Penthorum chinense Pursh suppresses hepatic stellate cells activation through a unified SIRT3-TGF-beta-Smad signaling pathway Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018,Volume: 341,Page: 38-50
Authors:  Zhou, Fayang;  Wang, Anqi;  Li, Dan;  Wang, Yitao;  Lin, Ligen
View  |  Adobe PDF(2014Kb)  |  Favorite  |  View/Download:291/16  |  Submit date:2018/10/30
Liver Fibrosis  Hepatic Stellate Cells  Penthorum Chinense Pursh  Pinocembrin  Sma- And Mad-related Proteins  Silent Mating Type Information Regulation 2 Homolog 3  
Discovery and preliminary SAR of 14-aryloxy-andrographolide derivatives as antibacterial agents with immunosuppressant activity Journal article
RSC ADVANCES, 2018,Volume: 8,Issue: 17,Page: 9440-9456
Authors:  Li, Feng;  Li, Xiao-Min;  Sheng, Dekuan;  Chen, Shao-Ru;  Nie, Xin;  Liu, Zhuyun;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Wang, Ying;  Zhou, Guo-Chun
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gamma-Mangostin, a xanthone from mangosteen, attenuates oxidative injury in liver via NRF2 and SIRT1 induction Journal article
JOURNAL OF FUNCTIONAL FOODS, 2018,Volume: 40,Page: 544-553
Authors:  Wang, Anqi;  Li, Dan;  Wang, Shengpeng;  Zhou, Fayang;  Li, Peng;  Wang, Yitao;  Lin, Ligen
View  |  Adobe PDF(1410Kb)  |  Favorite  |  View/Download:300/16  |  Submit date:2018/10/30
Gamma-mangostin  Mangosteen  Liver Oxidative Injury  Nrf2  Sirt1  Pgc-1 Alpha