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γ-Mangostin alleviates liver fibrosis through Sirtuin 3-superoxide-high mobility group box 1 signaling axis Journal article
Toxicology and Applied Pharmacology, 2019,Volume: 363,Page: 142-153
Authors:  Wang A.;  Zhou F.;  Li D.;  Lu J.-J.;  Wang Y.;  Lin L.
Favorite  |  View/Download:8/0  |  Submit date:2018/12/28
Fibrogenesis  HMGB1  Liver fibrosis  Sirtuin 3  Superoxide  γ-Mangostin  
Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2018,Volume: 26,Issue: 18,Page: 5053-5061
Authors:  Chen, Shao-Ru;  Li, Feng;  Ding, Mo-Yu;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Zhou, Guo-Chun;  Wang, Ying
View  |  Adobe PDF(2009Kb)  |  Favorite  |  View/Download:220/29  |  Submit date:2018/10/30
Andrographolide  Stat3 Inhibitor  Acute Liver Damage  Inflammation  
Toosendanin, a natural product, inhibited TGF-1-induced epithelial-mesenchymal transition through ERK/Snail pathway Journal article
PHYTOTHERAPY RESEARCH, 2018,Volume: 32,Issue: 10,Page: 2009-2020
Authors:  Luo, Weiwei;  Liu, Xin;  Sun, Wen;  Lu, Jin-Jian;  Wang, Yitao;  Chen, Xiuping
View  |  Adobe PDF(2621Kb)  |  Favorite  |  View/Download:174/20  |  Submit date:2018/10/30
Emt  Erk1/2  Snail  Lung Cancer  Toosendanin  
Honokiol protects hepatocytes from oxidative injury through mitochondrial deacetylase SIRT3 Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 834,Page: 176-187
Authors:  Liu, Jing-Xin;  Shen, Sheng-Nan;  Tong, Qiang;  Wang, Yi-Tao;  Lin, Li-Gen
Favorite  |  View/Download:24/0  |  Submit date:2018/10/30
Honokiol  Oxidative Stress  Liver  Sirt3  Mitochondria  Fragmentation  
Supramolecular strategy for reducing the cardiotoxicity of bedaquiline without compromising its antimycobacterial efficacy Conference paper
FOOD AND CHEMICAL TOXICOLOGY, Kunming, PEOPLES R CHINA, AUG 25-30, 2018
Authors:  Kuok, Kit Ieng;  Ng, Phoebe Choi In;  Ji, Xia;  Wang, Chunming;  Yew, Wing Wai;  Chan, Denise P. C.;  Zheng, Jun;  Lee, Simon M. Y.;  Wang, Ruibing
View  |  Adobe PDF(423Kb)  |  Favorite  |  View/Download:115/20  |  Submit date:2018/10/30
Cucurbit[7]Uril  Bedaquiline  Supramolecular Formulation  Cardiotoxicity  Antimycobacterial  
Physalin B induces cell cycle arrest and triggers apoptosis in breast cancer cells through modulating p53-dependent apoptotic pathway Journal article
BIOMEDICINE & PHARMACOTHERAPY, 2018,Volume: 101,Page: 334-341
Authors:  Wang, Anqi;  Wang, Shengpeng;  Zhou, Fayang;  Li, Peng;  Wang, Yitao;  Gan, Lishe;  Lin, Ligen
View  |  Adobe PDF(1614Kb)  |  Favorite  |  View/Download:92/11  |  Submit date:2018/10/30
Physalin b  Breast Cancer  Cell Cycle  Apoptosis  P53  Akt  
Skeletal muscle overexpression of short isoform Sirt3 altered mitochondrial cardiolipin content and fatty acid composition Journal article
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES, 2018,Volume: 50,Issue: 2,Page: 131-142
Authors:  Chabi, Beatrice;  Fouret, Gilles;  Lecomte, Jerome;  Cortade, Fabienne;  Pessemesse, Laurence;  Baati, Narjes;  Coudray, Charles;  Lin, Ligen;  Tong, Qiang;  Wrutniak-Cabello, Chantal;  Casas, Francois;  Feillet-Coudray, Christine
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Sirt3 isoforms  Mitochondria  Cardiolipin  Phospholipids  Skeletal muscle  
BRCA1 function in the intra-S checkpoint is activated by acetylation via a pCAF/SIRT1 axis Journal article
ONCOGENE, 2018,Volume: 37,Issue: 17,Page: 2343-2350
Authors:  Lahusen, Tyler J.;  Kim, Seung-Jin;  Miao, Kai;  Huang, Zebin;  Xu, Xiaoling;  Deng, Chu-Xia
Favorite  |  View/Download:18/0  |  Submit date:2018/10/30
Pinocembrin from Penthorum chinense Pursh suppresses hepatic stellate cells activation through a unified SIRT3-TGF-beta-Smad signaling pathway Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018,Volume: 341,Page: 38-50
Authors:  Zhou, Fayang;  Wang, Anqi;  Li, Dan;  Wang, Yitao;  Lin, Ligen
View  |  Adobe PDF(2014Kb)  |  Favorite  |  View/Download:80/6  |  Submit date:2018/10/30
Liver Fibrosis  Hepatic Stellate Cells  Penthorum Chinense Pursh  Pinocembrin  Sma- And Mad-related Proteins  Silent Mating Type Information Regulation 2 Homolog 3  
Acetylation of AGO2 promotes cancer progression by increasing oncogenic miR-19b biogenesis Journal article
Oncogene, 2018
Authors:  Hailong Zhang;  Yanli Wang;  Jinzhuo Dou;  Yanmin Guo;  Jianfeng He;  Lian Li;  Xiaojia Liu;  Ran Chen;  Rong Deng;  Jian Huang;  Ruiyu Xie;  Xian Zhao;  Jianxiu Y
Favorite  |  View/Download:1/0  |  Submit date:2019/01/17
Acetylation  Non-coding Rnas